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Colorectal adenoma subtypes exhibit signature molecular profiles: unique insights into the microenvironment of advanced precancerous lesions for early detection applications

Mattia Mancuso, Francesco · Higareda Almaraz, Juan Carlos · Canal Noguer, Pol + 4 authors

2025Publisher: Multidisciplinary Digital Publishing Institute (MDPI)Repository: UPCommons — Universitat Politècnica de Catalunya

Background: Colorectal cancer (CRC) is characterized by the uncontrolled growth of malignant colonic or rectal crypt epithelium. About 85% of CRCs evolve through a stepwise progression from advanced precancerous adenoma lesions. A better understanding of the evolution from…

DOI: 10.3390/cancers17040654

Conditional dependence via U-Statistics pruning

Cabrera Estanyol, Ferran de · Vila Insa, Marc · Riba Sagarra, Jaume

2025Repository: UPCommons — Universitat Politècnica de Catalunya

The problem of measuring conditional dependence between two random phenomena arises when a third one (a confounder) has a potential influence on the amount of information between them. A typical issue in this challenging problem is the inversion of ill-conditioned…

DOI: 10.1109/LSP.2025.3539587

Escaping dynamics of relativistic protons in the Earth's magnetosphere

Meseguer Serrano, Álvaro · Vallejo Chavarino, Juan Carlos · Seoane Sepúlveda, Jesús M. + 2 authors

2025Publisher: American Institute of Physics (AIP)Repository: UPCommons — Universitat Politècnica de Catalunya

In this work, we study the motion of protons under the influence of the Earth's magnetic field. We investigate the dynamics and topology of invariant spatial regions in two magnetic field models, namely, the dipolar and Luhmann tail configurations. In both cases, we analyze the…

DOI: 10.1103/PhysRevE.111.044216

Validity of recurrent neural networks to predict pedal forces and lower limb kinetics in cycling

Cordero Sánchez, Juan · Bini, Rodrigo · Serrancolí, Gil

2025Repository: UPCommons — Universitat Politècnica de Catalunya

Dynamic variables contribute to understand the mechanics of pedalling and can assist with injury prevention. Measuring pedal forces and joint moments and powers has a high cost, which can be mitigated by using trained artificial neural networks (ANN) to predict forces from…

DOI: 10.1016/j.jbiomech.2025.112619

Análisis de los contenedores marítimos y estudio para su reutilización

Martín-Albo Chapinal, Carlos

2025Repository: UPCommons — Universitat Politècnica de Catalunya

L’objectiu d’aquest treball és fer l'anàlisi d’un contenidor marítim i elaborar un estudi de reutilització, disminuint l’impacte ambiental de rebutjar-los completament a l’acabar la seva vida útil al sector del transport de mercaderies. Es realitzarà un marc teòric en el qual es…

Control para eliminación completa de tensión de secuencia negativa en una microred eléctrica basada en varios convertidores de potencia

Breña Diaz, Luis Alberto

2025Repository: UPCommons — Universitat Politècnica de Catalunya

A les microxarxes elèctriques, la presència de tensions de seqüència negativa a causa de desbalances de càrrega o pertorbacions pot afectar el rendiment dels convertidors, reduir la vida útil dels equips i generar ineficiències en la distribució d'energia. Aquest treball…