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3291+ documents found

Investigación y práctica en los márgenes de la regulación normativa de las Siedlungen de la postguerra de la región del Rin-Meno

Pelegrín Rodríguez, Marta · Pérez Blanco, Fernando

2025Publisher: Editorial Universidad de SevillaRepository: idUS — Universidad de Sevilla

El artículo introduce el trabajo de investigación que, ante la reciente política de rehabilitación de la vivienda social construida en Alemania durante la posguerra, prioritariamente centrada en la mejora de las condiciones constructivas y gasto energético, incorpora una…

DOI: 10.12795/astragalo.2025.i38.10

Sos1 ablation alters focal adhesion dynamics and increases Mmp2/9-dependent gelatinase activity in primary mouse embryonic fibroblasts

Liceras-Boillos, Pilar · Garcia-Navas, Rósula · Llorente-González, Clara + 4 authors

2025Publisher: Biomed central LTDRepository: idUS — Universidad de Sevilla

Background Sos1 and Sos2 are guanine-nucleotide exchange factors for Ras and Rac small GTPases, which are involved in a wide range of cellular responses including proliferation and migration. We have previously shown that Sos1 and Sos2 have different effects on cell migration…

DOI: 10.1186/s12964-025-02122-1

Imaging biomarkers of cortical neurodegeneration underlying cognitive impairment in Parkinson’s disease

Silva Rodríguez, Jesús · Labrador Espinosa, Miguel Ángel · Castro-Labrador, Sandra + 7 authors

2025Publisher: Springer NatureRepository: idUS — Universidad de Sevilla

Purpose: Imaging biomarkers bear great promise for improving the diagnosis and prognosis of cognitive impairment in Parkinson’s disease (PD). We compared the ability of three commonly used neuroimaging modalities to detect cortical changes in PD patients with mild cognitive…

DOI: 10.1007/s00259-025-07070-z

Ageing and ambient assisted living: new landscapes of dwelling

Quesada-García, Santiago

2025Publisher: Taylor & FrancisRepository: idUS — Universidad de Sevilla

As Le Corbusier famously stated, a house is not simply a machine for living, but a lived-in home. As we explore new technologies in construction and city planning, the concept of a smart city is taking shape. One exciting development is Active Assisted Living, which seeks to…

DOI: 10.4324/9781003144441-7

Suicide risk among cannabis, heroin and cocaine users

Pérez Sosa, Miguel Zacarías · Vega Sánchez, Diego de la · Sanz – Gómez, Sergio + 5 authors

2025Publisher: SpringerRepository: idUS — Universidad de Sevilla

Individuals who use substances such as cocaine, cannabis, heroin, alcohol and nicotine are at increased risk for suicidal behavior. Our objective is to examine the relationship between substance use and suicide. An observational psychological autopsy study design was used to…

DOI: 10.1007/s11469-025-01460-y

Calendario BUS 2025

Biblioteca de la Universidad de Sevilla

2025Repository: idUS — Universidad de Sevilla

Perception of English Vowel Sounds by Spanish Speakers

Fernández Grandes, Mónica

2025Repository: idUS — Universidad de Sevilla

This Study investigates how native Spanish speakers perceive English vowel sounds, focusing on contrasts that do not exist in Spanish, such as /iː/–/ɪ/, /ʊ/–/uː/, and /æ/–/ʌ/. The main aim is to identify which phonemes are most difficult to distinguish and how factors like…

Ética, jubileo y doctrina social de la Iglesia

Delgado Rojas, Jesús Ignacio

2025Publisher: Alma MaterRepository: idUS — Universidad de Sevilla

Aunque son diversas las temáticas sobre las que versa la Doctrina Social de la Iglesia, en esta ocasión me centraré en algunas consideraciones que tienen que ver con la Ética y el Jubileo y, sobre todo, quisiera acercar estas cuestiones a la plasmación que reciben hoy en un…

Engineering Inorganic Pyrophosphate Metabolism as a Strategy to Generate a Fluoride-Resistant Saccharomyces cerevisiae Strain

Pérez Castiñeira, José Román · Ávila Oliva, F. J. · Serrano, A.

2025Publisher: Multidisciplinary Digital Publishing Institute (MDPI)Repository: idUS — Universidad de Sevilla

Fluorine accounts for 0.3 g/kg of the Earth’s crust, being widely distributed in the environment as fluoride. The toxic effects of this anion in humans and other organisms have been known for a long time. Fluoride has been reported to alter several cellular processes although…

DOI: 10.3390/microorganisms13020226