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Multifaceted Sulfonamide-Derived Thiosemicarbazones: Combining Metal Chelation and Carbonic Anhydrases Inhibition in Anticancer Therapy

Martínez Montiel, Mónica · Arrighi, Giulia · Begines Aguilar, Paloma + 9 authors

2025Publisher: Multidisciplinary Digital Publishing Institute (MDPI)Repository: idUS — Universidad de Sevilla

The selective inhibition of key enzymes, such as carbonic anhydrases (CAs IX and XII), which are overexpressed in cancer tissues, has emerged as a promising strategy in cancer research. However, a multitarget approach is often preferred to achieve enhanced therapeutic outcomes…

DOI: 10.3390/ijms26031225

The Combination of Salicylic Acid, Nicotinamide, and Proline Mitigates the Damage Caused by Salt Stress in Nasturtium (Tropaeolum majus)

Santos, Thainan Sipriano dos · Correia, Marcos Roberto Santos · Sena, Luma Santos + 6 authors

2025Publisher: Multidisciplinary Digital Publishing Institute (MDPI)Repository: idUS — Universidad de Sevilla

Salinity represents a significant challenge for agriculture, especially in semi-arid regions, affecting the growth and productivity of plants such as nasturtium (Tropaeolum majus), which is valued for its ornamental, medicinal, and food uses. Salt stress disrupts biochemical…

DOI: 10.3390/plants14081156

Evaluación de objetos de Realidad Virtual en la educación: análisis de la usabilidad y aspectos técnicos y estéticos por estudiantes

Cabero Almenara, Julio · Miravete Gracia, María · Serrano Hidalgo, Manuel + 1 author

2025Publisher: Universidad de CádizRepository: idUS — Universidad de Sevilla

La investigación evalúa la usabilidad y los aspectos técnicos y estéticos de un objeto de realidad virtual (RV) desde la perspectiva de estudiantes universitarios. Se empleó un diseño no experimental, descriptivo y comparativo, con enfoque cuantitativo y de corte transversal…

DOI: 10.25267/Hachetetepe.2025.i30.1101

Puesta en marcha de un sistema Rapid Control Pro totyping (RCP) para el control de convertidores de potencia y verificación experimental con un converti dor DC/DC reductor interleaved

Castillo Pérez, Álvaro

2025Repository: idUS — Universidad de Sevilla

En este proyecto se lleva a cabo el diseño, construcción y puesta en marcha de un convertidor DC/DC reductor interleaved. El trabajo se plantea como un manual para su ensamblado y comprensión del hardware de control utilizado, la BBoard Pro de Imperix, así como el entorno que…

Transportation and delivery in flow-shop scheduling problems: A systematic review

Fernández-Viagas Escudero, Víctor

2025Publisher: ElsevierRepository: idUS — Universidad de Sevilla

This paper presents a literature review of flow-shop scheduling problems with transportation or delivery of jobs. Flow-shop scheduling problems are one of the most widely studied optimisation problems in the literature on Operations Research. Although these have traditionally…

DOI: 10.1016/j.ejor.2024.11.034

Stepwise alkyne insertion in Au(i) acetylides: influence of the nuclearity

Cayuela-Castillo, Juan · Fernández de Córdova, Francisco José · See, Matthew S. + 2 authors

2025Publisher: Royal Society of ChemistryRepository: idUS — Universidad de Sevilla

The reaction between NHC-supported (NHC = N-heterocyclic carbene) gold(I) trimethylsilylacetylide complexes with NHC gold(I) hydroxide species renders different symmetrical homobimetallic Au complexes. These compounds readily undergo migratory insertion of DMAD (dimethyl…

DOI: 10.1039/d4sc08227c

Integration of Artificial Intelligence and Machine Learning in Education: A Systematic Review

Reina Parrado, Manuel · Román Graván, Pedro · Hervás Gómez, Carlos

2025Publisher: RhapsodeRepository: idUS — Universidad de Sevilla

This PRISMA-based systematic review analyzes how artificial intelligence (AI) and Machine Learning (ML) are integrated into educational institutions, examining the challenges and opportunities associated with their adoption. Through a structured selection process, 27 relevant…

DOI: 10.12973/ijem.11.2.203

On the assessment of channel deepening impacts in micro-meso tidal estuaries: A systematic analysis

Martín Llanes, Guillermo · López-Ruiz, Alejandro

2025Publisher: ElsevierRepository: idUS — Universidad de Sevilla

The need for efficient maritime transportation in estuaries has led to the development of diverse dredging strategies to accommodate vessels with deep drafts. Most recent studies assessing the environmental impacts of channel deepening use advanced, tailored models to simulate…

DOI: 10.1016/j.ocemod.2025.102552

Effectiveness of the PElEO program to develop the entrepreneurial potential of Spanish students in Secondary Education and Vocational Training

Martín Gutiérrez, Ángela · Fernández Salinero, Miguel · García Mora, María Elena + 1 author

2025Publisher: Elsevier BVRepository: idUS — Universidad de Sevilla

The general aim of the investigation was to determine the effectiveness of the PElEO program (educational program for the development of entrepreneurial potential in adolescents) in Spanish students (males and females). It was carried out with a pre-test and post-test design in…

DOI: 10.1016/j.ssaho.2025.101365