scieee Science in your language
[en] (orig)

A Finite Element Analysis of a New Dental Implant Design: The Influence of the Diameter, Length, and Material of an Implant on Its Biomechanical Behavior

Abstract

It is widely recognized that excessive stress and/or strain can lead to peri-implant bone atrophy; therefore, the clinical success of dental implants is intrinsically related to their biomechanical behavior. This study evaluates the influence of the diameter, length, and material [Ti6Al4V (α+β Ti) and Ti35Nb7Zr5Ta (β-Ti)] of a novel cylindrical dental implant on stress and strain levels within maxillary bone of type II quality. The implant design aims to ensure an appropriate distribution of stresses and strains within the peri-implant bone structures (cortical and trabecular bones) while also facilitating surgical machining by requiring a simple, linear, and less expensive bone incision. This approach minimizes the risk of thermal necrosis, a common complication in osteotomies for conical implants that can lead to peri-implant bone loss. Using finite element analysis, stress and strain patterns were evaluated in the maxillary second premolar region under static delayed loading. The results reveal that the cortical bone strains remained below the critical threshold (0.003) to prevent resorption. In the trabecular bone, only larger diameter/length configurations satisfied the previous strain criterion. In all simulations, trabecular bone stress remained below 3 MPa, whereas cortical bone stress peaked at 78 MPa. Notably, the implant model with the largest diameter/length minimized stress and strain concentrations in type II bone when compared to smaller designs, thereby demonstrating its biomechanical advantage.

Read accessible full text

A Finite Element Analysis of a New Dental Implant Design: The Influence of the Diameter, Length, and Material of an Implant on Its Biomechanical Behavior

Author: González-Mederos, Pedro; Rodríguez-Guerra, Jennifer; González-Ruiz, Jesús Eduardo; Picardo Pérez, Alberto; Torres Hernández, Yadir
Publisher: MDPI
Year: 2025
DOI: 10.3390/ma18122692
Source: https://idus.us.es/bitstreams/4f4677c3-08cb-40de-891e-06f8e8d61e01/download
Academic Edi o : Bongju Kim
Recei ed: 2 May 2025
Re ised: 31 May 2025
Accep ed: 3 June 2025
Published: 7 June 2025
Ci a ion: González-Mede os, P.;
Rod íguez-Gue a, J.; González, J.E.;
Pica do, A.; To es, Y. A Fini e Elemen
Analysis o a New Den al Implan
Design: The In luence o he Diame e ,
Leng h, and Ma e ial o an Implan on
I s Biomechanical Beha io . Ma e ials
2025,18, 2692. h ps://doi.o g/
10.3390/ma18122692
Copy igh : © 2025 by he au ho s.
Licensee MDPI, Basel, Swi ze land.
This a icle is an open access a icle
dis ibu ed unde he e ms and
condi ions o he C ea i e Commons
A ibu ion (CC BY) license
(h ps://c ea i ecommons.o g/
licenses/by/4.0/).
A icle
A Fini e Elemen Analysis o a New Den al Implan Design: The
In luence o he Diame e , Leng h, and Ma e ial o an Implan on
I s Biomechanical Beha io
Ped o González-Mede os 1, Jenni e Rod íguez-Gue a 1, Jesús E. González 1,2,*, Albe o Pica do 3
and Yadi To es 4,*
1
Depa amen o de Bioma e iales Ce ámicos y Me álicos, Cen o de Bioma e iales, Uni e sidad de La Habana,
A e. Uni e sidad s/n En e G y Ronda, Vedado, La Habana 10400, Cuba;
[email p o ec ed] (P.G.-M.); jenni e [email p o ec ed] (J.R.-G.)
2G upo de Biomecánica, Facul ad de Mecánica, Uni e sidad Tecnológica de la Habana “José An onio
Eche e ía”, Di ección Calle 114, # 11901, e/Ciclo ía y Ro onda, Ma ianao, Cujae, La Habana 19390, Cuba
3
Depa amen o de Ingenie ía del Diseño, Escuela Poli écnica Supe io de Se illa, Uni e sidad de Se illa, Calle
Vi gen de Á ica, 7, 41011 Se illa, Spain; apica [email p o ec ed]
4Ingenie ía y Ciencia de los Ma e iales y del T anspo e, Escuela Poli écnica Supe io de Se illa, Uni e sidad
de Se illa, Calle Vi gen de Á ica, 7, 41011 Se illa, Spain
*Co espondence: [email p o ec ed] (J.E.G.); [email p o ec ed] (Y.T.)
Abs ac : I is widely ecognized ha excessi e s ess and/o s ain can lead o pe i-implan
bone a ophy; he e o e, he clinical success o den al implan s is in insically ela ed o hei
biomechanical beha io . This s udy e alua es he in luence o he diame e , leng h, and
ma e ial [Ti6Al4V (
α
+
β
Ti) and Ti35Nb7Z 5Ta (
β
-Ti)] o a no el cylind ical den al implan
on s ess and s ain le els wi hin maxilla y bone o ype II quali y. The implan design
aims o ensu e an app op ia e dis ibu ion o s esses and s ains wi hin he pe i-implan
bone s uc u es (co ical and abecula bones) while also acili a ing su gical machining by
equi ing a simple, linea , and less expensi e bone incision. This app oach minimizes he
isk o he mal nec osis, a common complica ion in os eo omies o conical implan s ha
can lead o pe i-implan bone loss. Using ini e elemen analysis, s ess and s ain pa e ns
we e e alua ed in he maxilla y second p emola egion unde s a ic delayed loading. The
esul s e eal ha he co ical bone s ains emained below he c i ical h eshold (0.003)
o p e en eso p ion. In he abecula bone, only la ge diame e /leng h con igu a ions
sa is ied he p e ious s ain c i e ion. In all simula ions, abecula bone s ess emained
below 3 MPa, whe eas co ical bone s ess peaked a 78 MPa. No ably, he implan model
wi h he la ges diame e /leng h minimized s ess and s ain concen a ions in ype II bone
when compa ed o smalle designs, he eby demons a ing i s biomechanical ad an age.
Keywo ds: den al implan ; ini e elemen analysis; biomechanical beha io ; s ess shielding
Phenomenon; β-Ti alloy; implan dimensions
1. In oduc ion
In ecen decades, subs an ial p og ess has been achie ed in p os he ic den is y,
leading o no able imp o emen s in bo h den al implan echnology and su gical echniques.
The p ima y ocus o hese ad ances has been o ensu e p edic able clinical ou comes while
simul aneously enhancing unc ional pe o mance and es he ic esul s in pa ien s wi h
comple e o pa ial eden ulism [
1
]. The e icacy o p os he ic ehabili a ion depends on
mul iple a iables ha can in luence he biomechanical in e ac ion be ween he implan
Ma e ials 2025,18, 2692 h ps://doi.o g/10.3390/ma18122692
Ma e ials 2025,18, 2692 2 o 20
and he osseous issue [
2
,
3
]. These ac o s encompass he exac posi ioning o he implan ,
he inhe en mechanical and s uc u al p ope ies o he bone issue, he mechanical and
geome ic ea u es o he implan i sel , and he in ensi y and ype o load ansmi ed
om he implan o he su ounding bone [
4
–
6
]. Addi ionally, i is necessa y o conside
pa ien -speci ic ac o s such as smoking habi s and bac e ial en i onmen [7–9].
The success o den al implan ea men depends, among o he ac o s, on he e icien
ans e o occlusal loads a he bone–implan in e ace [
10
]. Mul iple elemen s, including
he loading egimen, implan su ace opog aphy, a ailable bone olume, as well as he ma-
e ial p ope ies and design cha ac e is ics o he implan , in luence his load ans e [
11
].
An op imal design can mi iga e s ess and s ain concen a ions while imp o ing hei
dis ibu ion pa e ns, hus imp o ing he p obabili y o long- e m implan su i al [
12
].
S ess and s ain dis ibu ions in he pe i-implan bone a e di ec ly a ec ed by he na u e
o he applied load [
13
]. Excessi e mechanical loading (o e load condi ions) may ini ia e
bone mic o- ac u es, po en ially leading o implan loosening o ca as ophic ailu e. Fu -
he mo e, o e load si ua ions can cause accele a ed bone eso p ion in he pe i-implan
egion and educe abecula bone densi y [
14
]. Rega ding implan ma e ials, hey mus
demons a e essen ial cha ac e is ics including biocompa ibili y, s uc u al du abili y, and
supe io esis ance o co osion, wea , and mechanical ac u e [15].
The selec ion o an app op ia e den al implan necessi a es a comp ehensi e e alua ion
o he esidual al eola bone, inco po a ing an assessmen o he e ical bone heigh
and mesiodis al dimensions o he eden ulous space, o achie e op imal biomechanical
pe o mance and es he ic esul s [
16
,
17
]. Clinical guidelines ecommend main aining a
minimum dis ance o 1.25 mm be ween an implan and adjacen na u al ee h, p o iding
adequa e space o suppo bone and pe iodon al ligamen issue while ensu ing su icien
ascula supply o success ul osseoin eg a ion. Addi ionally, a minimum ci cum e en ial
bone hickness o 0.5 mm su ounding he implan mus be p ese ed o ensu e he long-
e m clinical s abili y and success o p os he ic ehabili a ion [18,19]. Pos -ex ac ion bone
eso p ion in he maxilla leads o educed esidual bone heigh , pa icula ly in he pos e io
egion, whe e p oximi y o he maxilla y sinus complica es he placemen o s anda d-
leng h implan s [
20
]. Al hough bone g a ing and sinus li p ocedu es a e well-es ablished
ea men op ions, hey a e associa ed wi h inc eased mo bidi y and a p olonged du a ion
o ea men . Sho implan s p o ide a minimally in asi e solu ion wi hou comp omising
p ima y s abili y as la ge diame e s and op imized implan body geome y can compensa e
o educed leng h, he eby enhancing ini ial e en ion in low-densi y maxilla y bone [
21
].
I is impo an o no e ha bone issue esponds o al e a ions in he loading condi ions
o which i is subjec ed. This phenomenon, known as bone emodeling, in ol es he
abili y o he bone o adap and modi y i sel o achie e a balance be ween s eng h and
esis ance [
22
–
24
]. Howe e , o e load condi ions can lead o bone ac u e, a igue ailu e,
and de imen al consequences, including ma ginal bone loss o e en osseoin eg a ion
ailu e [
25
,
26
]. Pe i-implan bone eso p ion can be igge ed by a ious ac o s, such as
su gical auma, bac e ial in ec ions, and s a es o o e load o unde load, bu o a lesse
ex en [
6
,
27
,
28
]. O e load in he pe i-implan bone can occu due o de iciencies in he
load ans e mechanisms, such as malocclusion, inco ec use o he implan , inco ec
design o he p os he ic c own and/o implan , and imp ope placemen o he implan .
Consequen ly, his can esul in high s ess concen a ions and/o s ains a he bone–
implan in e ace and, ul ima ely, bone eso p ion [29,30].
In essence, biomechanical load ans e a he bone–implan in e ace cons i u es a
c i ical de e minan o den al implan success. Op imal implan design, including i s
geome y, diame e , leng h, and h ee-dimensional posi ioning wi hin he maxilla, plays a
pi o al ole in go e ning he occlusal load dis ibu ion and he subsequen bone adap i e
Ma e ials 2025,18, 2692 3 o 20
esponse [
31
–
33
]. A design ha p omo es a balanced load dis ibu ion and minimizes s ess
concen a ions can help p e en bone eso p ion and imp o e he du abili y and clinical
e ec i eness o implan ehabili a ions [34–36].
The use o ini e elemen analysis (FEA) in p os he ic den is y has become a p edom-
inan quan i a i e me hod o in es iga e he biomechanical beha io o den al implan s
in a ious clinical scena ios [
37
,
38
]. This echnique enables he p edic ion o s ess and
s ain dis ibu ions in pe i-implan egions while conside ing mul iple a iables, including
implan and p os hesis design, load magni ude and di ec ion, bone mechanical p ope ies,
and o he case-speci ic condi ions [
39
]. The p incipal ad an age o he FEA me hod lies in
i s abili y o simula e he complexi y o eal clinical si ua ions. Enabling he modeling o
complex geome ies and ma e ials and he in e ac ions be ween a ious componen s o he
biomechanical sys em acili a es a mo e accu a e unde s anding o he mechanical beha io
wi hin bone [
40
,
41
]. Consequen ly, his app oach allows o he iden i ica ion o po en ial
o e loaded egions o unde loaded zones ha may igge bone eso p ion o implan
ailu e [
42
–
44
]. Howe e , i mus be ecognized ha FEA s udies a e no exemp om
ce ain assump ions and limi a ions. These encompass he selec ion o ma e ial p ope -
ies, bounda y condi ion de ini ions, in e ace cha ac e iza ions be ween componen s, and
he gene al modeling me hodology [
35
,
45
]. The alidi y o FEA-de i ed esul s depends
on he igo o hese assump ions and conside a ions and on he p ecise expe imen al
alida ion o he models. Fu he mo e, hese esul s a e used o op imize he design o
den al implan s by inco po a ing modi ica ions in geome y and dimensions [
46
,
47
]. In
summa y, using FEA o examining den al implan biomechanics o e s signi ican bene i s
by enabling comp ehensi e simula ion and analysis o complex bone–implan sys em
in e ac ions [
48
]. Ne e heless, he esul s mus be in e p e ed cau iously as hey emain
subjec o he inhe en assump ions and limi a ions o he modeling app oach, as p e iously
ou lined [49].
Ti6Al4V (
α
+
β
Ti) alloys a e widely used in implan applica ions. Howe e , hei high
elas ic modulus (~110 GPa) and limi ed bioac i i y can lead o s ess concen a ions a he
bone–implan in e ace and con ibu e o pe i-implan bone eso p ion. In con as ,
β
-phase
i anium alloys such as Ti35Nb7Z 5Ta (
β
-Ti) p esen signi ican ad an ages, including a
lowe elas ic modulus (~55 GPa), mo e simila o co ical bone (~10–30 GPa), along wi h
imp o ed co osion esis ance and biocompa ibili y [
50
]. Recen compu a ional and
in i o
s udies ha e shown ha
β
-Ti alloys p omo e mo e a o able s ain dis ibu ions, educing
s ess shielding and imp o ing load ans e a he bone–implan in e ace. Howe e ,
comp ehensi e e alua ions o hei mic omechanical beha io emain limi ed [51].
Al hough widely used, conical implan s exhibi c i ical biomechanical and su gical
limi a ions: (1) hei design induces s ess concen a ion a he apex, inc easing he isk
o mic o ac u es in high-densi y bone ( ypes I and II); (2) complex bone p epa a ion ( a-
pe ed su gical d illing) may cause o e hea ing and nec osis, leading o co ical bone loss,
and (3) educed ini ial bone- o-implan con ac a he apical po ion comp omises ea ly
osseoin eg a ion [
52
]. Cylind ical implan s o e key ad an ages as a po en ial solu ion:
(a) uni o m
load dis ibu ion by elimina ing localized s ess poin s; (b) simpli ied (s aigh )
and less in asi e os eo omy, p ese ing bone in eg i y and minimizing he mal isks;
and (c) g ea e ini ial bone con ac a ea, enhancing osseoin eg a ion in high-densi y bone
( ype II) [
53
]. The s anda dized d illing p o ocol o cylind ical implan s educes su gical
ime, ins umen cos s, and he mal complica ions compa ed o conical sys ems, o e ing
signi ican economic ad an ages in high-densi y bone [
54
]. This pe spec i e challenges
he app oach pa adigm, sugges ing ha cylind ical designs op imize bo h biomechanical
pe o mance and cos -e iciency in speci ic bone pheno ypes, wi h di ec implica ions o
clinical planning and long- e m implan longe i y. A no el single-componen cylind ical
Ma e ials 2025,18, 2692 4 o 20
den al implan was designed, o e ing signi ican ad an ages: i elimina es he mic ogap
and connec ion in e aces p esen in wo-piece sys ems, which a e p one o bac e ial colo-
niza ion, sc ew loosening, and gal anic co osion. In addi ion, i imp o es biomechanical
s abili y by dis ibu ing occlusal o ces uni o mly h ough a single-uni s uc u e, educing
s ess concen a ion a p os he ic junc ions, and i simpli ies clinical wo k lows by a oiding
abu men sea ing inaccu acies, he eby imp o ing p ima y s abili y, a key equi emen o
ea ly unc ional loading.
The objec i e o his s udy is o assess he impac o he diame e , leng h, and ma e ial
(Ti6Al4V (
α
+
β
Ti) and Ti35Nb7Z 5Ta (
β
-Ti)) on he biomechanical beha io o a new
cylind ical den al implan model. Speci ically, i s in luence was e alua ed on he maximum
le els o on Mises equi alen s esses and on Mises s ains in he pe i-implan bone
(co ical and abecula bone) o he second p emola egion o he maxilla y.
2. Ma e ials and Me hods
2.1. Den al Implan Models
The geome y o a single-componen den al implan model used in p e ious s ud-
ies was modi ied o educe p oduc ion cos s and simpli y i s ancho ing p ocess in he
maxilla [
55
,
56
]. Speci ically, he ape o he e e enced design was signi ican ly educed.
Based on hese modi ica ions, six a ian s o he new single-componen den al implan
model (Figu e 1) we e ob ained in he Au odesk In en o 2020 so wa e (Au odesk Inc.,
San F ancisco, CA, USA), di e en ia ed by hei leng h and diame e alues (Table 1). The
implan s had a h ead ha ex ended h oughou he leng h o he implan body o which a
second h ead was added in he p oximal a ea (close o i s neck), bo h wi h a ec angula
p o ile. In he implan body, wo helical g oo es we e ex ended o enable sel - apping
in o he maxilla y bone. Fu he mo e, o de e mine he in luence o i s dimensions on
i s biomechanical beha io , he leng h o he h eaded po ion (implan body, L) and he
diame e o i s neck (D) we e a ied (Table 1).
Figu e 1. The cylind ical implan design used in he simula ions and i s main pa ame e s.
Ma e ials 2025,18, 2692 5 o 20
Table 1. Expe imen al design.
Expe imen al Run Implan Pa ame e
D (mm) L (mm)
A 3.7 8
B 3.7 10
C 3.7 12
D 4.0 8
E 4.0 10
F 4.0 12
2.2. The Assembly o he C own Den al Implan Sys em
To place he implan s, he maxilla model ob ained by Pé ez om medical image
p ocessing was used [
57
]. The maxilla model, including adjacen ee h o he p emola , was
modeled as a single solid body. Cu s we e made o he model, and a geome y smoo hing
p ocess was ca ied ou a he limi s o he p emola a ea o acili a e p ocessing in he
simula ion so wa e.
In Au odesk In en o so wa e, he six den al implan models we e assembled wi h a
ce amic c own, co esponding o he second p emola . Then, h eaded holes we e designed
in he jaw acco ding o he dimensions o each den al implan , and he c own den al implan
sys ems we e placed in hese o o m ou assemblies. Subsequen ly, he assemblies we e
expo ed in .sa o ma o he Abaqus/CAE simula ion so wa e (6.13).
2.3. Analysis Using he Fini e Elemen Me hod
The on Mises equi alen s ess (VMES) and on Mises s ain alues (VMS) in he
co ical and abecula bones we e ob ained by he FEA using he Abaqus/CAE simula ion
so wa e (Simulia Co p, Vélizy-Villacoublay, F ance, e sion 6.13). The sys em componen s
we e expo ed o Abaqus as sepa a e pa s, whe e ma e ial de ini ions we e es ablished
and he mechanical p ope ies speci ied in Table 2we e assigned. Co ical and abecula
bone ( ype II quali y) we e modeled wi h aniso opic ma e ial p ope ies, while iso opic
p ope ies we e assigned o he implan and c own. Addi ionally, all ma e ials we e ea ed
as homogeneous olumes exhibi ing linea elas ic beha io .
Table 2. The p ope ies o he ma e ials used in he sys em componen s.
Ma e ial Young’s Modulus,
E (MPa)
Shea Modulus,
G (MPa)
Poisson’s Ra io,
νRe e ences
Ti6Al4V
(den al implan ) 110,000 - 0.32 [58]
Ti35Nb7Z 5Ta (β-Ti)
(den al implan ) 55,000 - 0.32 [59]
Feldspa hic ce amic
(c own) 82,800 - 0.35 [60]
Co ical bone
Ex = 17,900 *
Ey = 26,600
Ez = 12,500
Gyx = 4500
Gyz = 7100
Gxz= 5300
νxy = 0.26
νxz = 0.31
νyz = 0.28 [61]
T abecula bone
Ex = 1148
Ey = 1148
Ez = 21
Gyx = 68
Gyz = 434
Gxz = 68
νxy = 0.05
νxz = 0.055
νyz = 0.322
* X—bucco-lingual di ec ion; Y—mesio-dis al di ec ion; Z—axial di ec ion (in e o-supe io ).
In e ac ions we e es ablished be ween he con ac su aces o he sys em componen s,
conside ing he physical unions ha exis be ween hese elemen s, wi h he use o a Tie

Ma e ials 2025,18, 2692 6 o 20
ype es ic ion, which implies ha he condi ion o he de ined su aces is a single one. A
global mesh (Figu e 2a), wi h e ahed al elemen s wi h an app oxima e size o 0.7 mm
was implemen ed, whe eas a locally e ined mesh wi h a size o 0.2 mm was used on
con ac su aces. The numbe o nodes and sys em elemen s in all simula ions depends
on he size o he mesh and a ies acco ding o changes in implan geome y. The sys em
wi h he smalles implan dimensions (3.7 and 8 mm) has he lowes numbe o elemen s
and nodes (1,826,206 elemen s and 339,497 nodes), whe eas he sys em wi h he la ges
implan dimensions (4.0 and 12 mm) exhibi s he highes alues o hese pa ame e s
(1,888,761 elemen s and 349,037 nodes). To gua an ee he accu acy o he s ess and s ain
alues ob ained, a con e gence es was ca ied ou , main aining he load and bounda y
condi ions. In his es , a e ahed al mesh wi h a e inemen o 0.16 mm was used o he
con ac su aces, and a e inemen o 0.6 mm was used in he global mesh. The esul was
an e o o less han 2%.
Figu e 2. The ancho age o he den al implan in he maxilla wi h he sys em mesh (a) and bounda y
condi ions and he di ec ion o he loads used in he simula ions (b).
A delayed loading condi ion was simula ed, conside ing he implan as ully osseoin e-
g a ed. Mul idi ec ional occlusal loads we e applied simul aneously along h ee ana omical
axes: axial (117 N), bucco-lingual (21.58 N), and mesio-dis al (29.48 N). Conside ing ha
he implan was ancho ed a he second p emola si e, he applied loads sligh ly inc eased
compa ed o hose used by Himmlo á e al. o a i s p emola [
62
]. The occlusal su ace
was modeled as he en i e c own su ace o he p emola , wi h loads applied ac oss a se
o 30 nodes dis ibu ed on mos o i s geome y o ensu e physiologically ep esen a i e
o ce applica ion (Figu e 2b). This app oach allowed o balanced load ansmission while
accoun ing o ana omical a iabili y (e.g., cusp inclina ion and ma ginal idges) o ensu e
p ope load dis ibu ion. By conside ing he en i e occlusal su ace a he han isola ed
con ac poin s, he model mo e accu a ely eplica es
in i o
loading condi ions, whe e
mas ica ion o ces a e dis ibu ed ac oss he c own. Bounda y condi ions we e imple-
men ed by ully cons aining he bone model, es ic ing all deg ees o eedom o simula e
embedded condi ions.
2.4. Expe imen al Design and S a is ical Analysis
This s udy e alua ed he in luence o wo key pa ame e s on he s ess and s ain
le els in pe i-implan co ical and abecula bone. Th ee di e en h eaded po ion leng hs
(Ls) and wo implan neck diame e s (Ds) we e analyzed using he ini e elemen me hod
simula ions. Consequen ly, he expe imen al design consis ed o six es con igu a ions, as
de ailed in Table 1. The diame e and leng h pa ame e alues used in he simula ed den al
implan models all wi hin he anges used in implan s p oduced by a ious comme cial
manu ac u e s. Howe e , o he leng h alues, expe imen al uns A and D a e conside ed
sho implan s. Six expe imen al uns we e pe o med using he Ti6Al4V alloy, supple-
Ma e ials 2025,18, 2692 7 o 20
men ed by wo addi ional uns (smalles and la ges implan designs A and F) employing
β- i anium Ti35Nb7Z 5Ta.
All s ess and s ain alues we e ex ac ed om he expe imen al uns in he abecula
and co ical bones, and he 300 mos loaded nodes gene a ed by each expe imen al un
we e selec ed o e alua e he biomechanics o he den al implan . The selec ed nodes
we e compiled in Mic oso O ice Excel; subsequen ly, he da a shee s we e expo ed o
S a G aphics Cen u ion XIX so wa e ( .19) (S a poin Technologies Inc., Wa en on, VA,
USA). In his so wa e, box-and-whiske analysis was used o de e mine he VMES and
abe an VMS alues. The alues we e subjec ed o a no mali y es (Kolmogo o –Smi no
es ) and subsequen ly analyzed using an analysis o a iance (ANOVA). Addi ionally, a
K uskal–Wallis es was used o iden i y di e ences be ween g oups, and a alue o
p< 0.05
conside ed s a is ically signi ican .
3. Resul s and Discussion
3.1. S ess and S ain Dis ibu ion Pa e ns in Co ical Bone Using Ti6Al4V (α+βTi)
The VMES dis ibu ions and VMS dis ibu ions gene a ed in co ical bone by he
expe imen al uns a e p esen ed in Figu es 3and 4. All e alua ed models p oduced
simila dis ibu ion pa e ns o bo h pa ame e s, cha ac e ized by peak concen a ions in
pe i-implan bone, pa icula ly in he maxilla y supe io egion adjacen o he implan
necks. This obse ed beha io aligns wi h he indings epo ed in p e ious s udies
in ol ing a ini e elemen analysis o den al implan s [
40
,
63
,
64
]. The maximum alues
o bo h mechanical pa ame e s we e consis en ly loca ed a ound he dis al aspec , while
he minimum alues occu ed p edominan ly in a eas in e acing wi h abecula bone.
Rega ding he supe io maxilla y egion, he peak alues o on Mises equi alen s esses
(MVMES) and s ains (MVMS) demons a ed dimensional dependence, which a ied
acco ding o implan geome ic pa ame e s.
Figu e 3. The dis ibu ion o on Mises equi alen s esses in he ex e nal su ace o co ical bone
su ounding he Ti6Al4V (
α
+
β
Ti) den al implan . No e: The le e s indica e he expe imen al un
(see Table 1).
Ma e ials 2025,18, 2692 8 o 20
Figu e 4. The on Mises s ain dis ibu ion in he ex e nal su ace o co ical bone adjacen o he
Ti6Al4V (α+βTi) den al implan . The le e s indica e he expe imen al un (see Table 1).
S ess and S ain Dis ibu ion Pa e ns in Co ical Bone Using Ti35Nb7Z 5Ta (β-Ti)
Figu e 5shows he on Mises s ess and s ain dis ibu ions in co ical bone o
implan s wi h smalle and la ge dimensions ( uns A and F). Bo h implan designs p oduced
simila s ess and s ain pa e ns unde he same condi ions, showing simila esul s o
hose gene a ed by Ti6Al4V den al implan s and p esen ing he highes alues concen a ed
in he pe i-implan bone, a ound he implan neck in he supe io maxilla. These esul s a e
consis en wi h p e ious ini e elemen s udies o den al implan s [
40
,
59
,
60
]. The maximum
alues o VMES and VMS we e obse ed a he dis al si e, while he lowes alues we e
ound in egions adjacen o abecula bone. In he supe io maxilla y a ea, he peak
magni udes o VMES (MVMES) and VMS (MVMS) exhibi ed dimensional dependence,
co ela ing wi h a ia ions in implan geome y.
Ma e ials 2025,18, 2692 9 o 20
Figu e 5. The dis ibu ion o on Mises equi alen s esses (S) and on Mises s ains (E) in he
ex e nal su ace o pe i-implan co ical bone using he Ti35Nb7Z 5Ta (
β
-Ti) implan . The le e s
indica e he expe imen al un (see Table 1).
3.2. Dis ibu ion Pa e ns o S esses and S ains in T abecula Bone Using Ti6Al4V (α+βTi)
Figu es 6and 7p esen he VMES and VMS dis ibu ions in he abecula bone o
all expe imen al con igu a ions. The peak alues o bo h pa ame e s we e concen a ed
p ima ily in wo egions: (1) in he in e ace wi h he apical zone o he implan , and
(2) o
s ain dis ibu ions speci ically, he h eaded implan su ace a he dis al si e. This
mechanical beha io s ems om he geome y o he h ead ac ing as a s ess concen a ion
ea u e due o i s complex h ee-dimensional mo phology.
The implan models p oduced compa able s ess and s ain dis ibu ion pa e ns in
he abecula bone, wi h educed alues o bo h mechanical pa ame e s obse ed in
egions in e acing wi h he double- h eaded po ion. Howe e , a ian s C and F (which
ea u e longe s em leng hs) demons a ed mo e uni o m dis ibu ion pa e ns. Speci ically,
hese con igu a ions showed diminished di e ences be ween VMES and VMS alues when
compa ing dis al e sus mesial si es, as well as be ween pe i-implan bone egions adjacen
o apical e sus p oximal implan sec ions.
Dis ibu ion Pa e ns o S esses and S ains in T abecula Bone Using Ti35Nb7Z 5Ta (
β
-Ti)
The FEA o he VMES and VMS dis ibu ions in abecula bone o he la ges and
smalles implan dimensions ab ica ed using Ti35Nb7Z 5Ta (
β
-Ti) a e shown in Figu e 8.
Consis en wi h he simula ions using he Ti6Al4V alloy, he implan wi h he la ges
leng h and diame e dimensions (F) exhibi ed a signi ican educ ion in he peak VMES
and VMS alues in he abecula bone compa ed o hose gene a ed by a ian A. Highe
VMES alues we e ound a he bone–implan in e ace nea he apical egion, while
peak VMS alues we e concen a ed a ound he dis al h eads, likely due o he ab up
changes in geome y. These esul s highligh he combined mechanical e ec o implan
ea u es: he apical engagemen suppo s p ima y s abili y, while he h ead design a ec s
Ma e ials 2025,18, 2692 16 o 20
o s ess dis ibu ion. These indings highligh ha while
β
-Ti o e s heo e ical ad an-
ages o bone emodeling, i s clinical applica ion equi es ca e ul conside a ion o implan
design and pa ien bone quali y o p e en ha m ul o e loads, pa icula ly in abecula
bone egions.
Fo he clinical implemen a ion o he de eloping implan model, e idence sugges s
p e e en ial selec ion o implan a ian s o maximum diame e and maximum leng h,
con ingen on adequa e dimensions o he ecipien jawbone. Howe e , se e al s udy
limi a ions cons ain he di ec clinical ex apola ion o hese indings. Fi s , he simula ion
me hodology used s a ic loading condi ions unde delayed loading assump ions. Second,
c i ical a iables including pe i-implan bone quali y a ia ions and implan posi ioning
wi hin he jaw we e no inco po a ed in he biomechanical analysis. Consequen ly, u u e
esea ch should ocus on (1) using FEM o in es iga e he e ec s o hese unexamined
a iables on pe i-implan s ess/s ain dis ibu ions and (2) alida ing cu en indings
h ough expe imen al es ing, including con olled in i o expe imen a ion.
4. Conclusions
This in es iga ion employed ini e elemen analysis o assess he biomechanical pe -
o mance o a no el den al implan design, wi h pa icula ocus on e alua ing how he
implan leng h and diame e in luence MVMES and MVMS in pe i-implan bone. The main
indings a e as ollows:
1.
Peak s ess concen a ions occu ed in pe i-implan co ical bone, pa icula ly in he
maxilla y su ace egion adjacen o he implan neck. This mechanical beha io
s ems om he ele a ed Young’s modulus o he co ical bone, which enhances i s
load-bea ing capaci y. On he con a y, he maximum s ain alues we e localized in
he abecula bone egions.
2.
Bo h heimplan diame e andleng hdemons a eds a is ically signi ican e ec s(
p< 0.05
)
on he peak equi alen s ess and s ain alues in co ical and abecula bone.
3.
Implan diame e eme ged as he dominan a iable a ec ing mechanical esponse,
a ibu able o inc eased implan –bone con ac a ea ha p omo es load dissipa ion
and consequen ly educes pe i-implan s ess/s ain magni udes.
4.
Supe io biomechanical ou comes consis en ly co ela ed wi h la ge implan dimen-
sions, sugges ing enhanced clinical pe o mance po en ial o c own–implan sys ems
ea u ing maximum diame e and leng h con igu a ions.
5.
The ma e ial o he den al implan demons a ed a s a is ically signi ican in luence
(
p< 0.05
) on he maximum le els o s ess and s ain gene a ed in he co ical and a-
becula bones. In gene al, he Ti35Nb7Z 5Ta alloy implan s showed highe maximum
alues o VMES and VMS han hose gene a ed by Ti6Al4V alloy implan s.
Au ho Con ibu ions: P.G.-M.: Concep ualiza ion, Me hodology, In es iga ion, Fo mal Analysis,
Valida ion, and W i ing—O iginal D a . J.R.-G.: In es iga ion, Concep ualiza ion, Me hodology,
Fo mal Analysis, Valida ion, and W i ing—O iginal D a . J.E.G.: P ojec Adminis a ion, Concep ual-
iza ion, Me hodology, Supe ision, W i ing—O iginal D a , and W i ing—Re iew and Edi ing. A.P.:
Me hodology, W i ing—O iginal D a , and W i ing—Re iew and Edi ing. Y.T.: Concep ualiza ion,
P ojec Adminis a ion, Supe ision, Me hodology, W i ing—O iginal D a , and W i ing—Re iew
and Edi ing. All au ho s ha e ead and ag eed o he published e sion o he manusc ip .
Funding: This publica ion is pa o p ojec PID2022-137911OB-I00, unded by MICIU/AEI/10.13039/
501100011033 and by ERDF/EU. Also, he Minis y o Science and Inno a ion o Spain o hei
con ibu ion o he p ojec h ough g an PDC2022-133369-I00, as well as, he p ojec PN385LH007-
035: 9827 o he Cuban Na ional Science and Technology p og am: Bio- echnology, Pha maceu ical
Indus y, and Medical Technologies.

Ma e ials 2025,18, 2692 17 o 20
Ins i u ional Re iew Boa d S a emen : No applicable.
In o med Consen S a emen : No applicable.
Da a A ailabili y S a emen : The o iginal con ibu ions p esen ed in his s udy a e included in he
a icle. Fu he inqui ies can be di ec ed o he co esponding au ho s.
Acknowledgmen s: The au ho s would like o hank he labo a o y echnicians a he Uni e si y o
Se ille o hei suppo in cha ac e izing he implan p o o ypes unde de elopmen o co obo a e
he esul s o he ini e elemen models p esen ed in his wo k.
Con lic s o In e es : The au ho s decla e no con lic s o in e es .
Abb e ia ions
The ollowing abb e ia ions a e used in his manusc ip :
FEA Fini e elemen analysis
VMES on Mises equi alen s ess
VMS on Mises s ain
MVMES Maximum on Mises equi alen s ess
MVMS Maximum on Mises s ain
Re e ences
1.
Alghamdi, H.S.; Jansen, J.A. The de elopmen and u u e o den al implan s. Den . Ma e . J. 2020,39, 167–172. [C ossRe ]
[PubMed]
2.
Bazli, L.; Kho amabadi, H.N.; Chaha dehi, A.M.; A sad, H.; Malekpou i, B.; Jazi, M.A.; Azizabadi, N. Fac o s in luencing he
ailu e o den al implan s: A Sys ema ic Re iew. J. Compos. Compd. 2019,2, 18–25. [C ossRe ]
3.
Yang, Y.; Hu, H.; Zeng, M.; Chu, H.; Gan, Z.; Duan, J.; Rong, M. The su i al a es and isk ac o s o implan s in he ea ly s age:
A e ospec i e s udy. BMC O al Heal h 2021,21, 293. [C ossRe ]
4.
Hasanoglu E basa , G.N.; Hocao˘glu, T.P.; E basa , R.C. Risk ac o s associa ed wi h sho den al implan success: A long- e m
e ospec i e e alua ion o pa ien s ollowed up o up o 9 yea s. B az. O al Res. 2019,33, e030. [C ossRe ] [PubMed]
5.
K isam, J.; O , L.; Schmi z, S.; Klo z, A.-L.; Seyidaliye a, A.; Rammelsbe g, P.; Zen hö e , A. Fac o s a ec ing he ea ly ailu e o
implan s placed in a den al p ac ice wi h a specializa ion in implan ology–a e ospec i e s udy. BMC O al Heal h 2019,19, 208.
[C ossRe ]
6.
Nimbalka , S.; Dha ak, P.; Ghe de, C.; Joshi, S. A e iew a icle on ac o s a ec ing bone loss in den al implan s. Ma e . Today
P oc. 2021,43, 970–976. [C ossRe ]
7.
¸Sahin, T. The e ec o indi iduals’ o al hygiene habi s and knowledge le els on pe i-implan heal h and disease: A ques ionnai e-
based obse a ional s udy. BMC O al Heal h 2024,24, 443. [C ossRe ]
8.
Malmq is , S.; E denbo g, J.; Johannsen, G.; Johannsen, A. Pa ien ’s expe iences o den al implan s, pe i-implan i is and i s
ea men -A quali a i e in e iew s udy. In . J. Den . Hyg. 2024,22, 530–539. [C ossRe ]
9.
Co ellini, S.; Fa il, C.; De Nu e, M.; Teughels, W.; Qui ynen, M. Pa ien compliance as a isk ac o o he ou come o implan
ea men . Pe iodon ology 2000 2019,81, 209–225. [C ossRe ]
10. Sadowsky, S.J. Occlusal o e load wi h den al implan s: A e iew. In . J. Implan Den . 2019,5, 29. [C ossRe ]
11. Robinson, D.; Aguila , L.; Ga i, A.; Abduo, J.; Lee, P.V.S.; Ackland, D. Load esponse o he na u al oo h and den al implan : A
compa a i e biomechanics s udy. J. Ad . P os hodon . 2019,11, 169–178. [C ossRe ] [PubMed]
12.
Szajek, K.; Wie szycki, M. Sc ew p eload loss unde occlusal load as a p edic o o loosening isk in a ying den al implan
designs. J. Mech. Beha . Biomed. Ma e . 2023,148, 106165. [C ossRe ]
13.
Pé ez-Pe ida, E.; Chá a i-P ado, D.; Diéguez-Pe ei a, M.; Es ada-Ma ínez, A.; Mon albán-Vadillo, O.; Jiménez-Ga udo, A.
Consequences o pe i-implan bone loss in he occlusal load ans e o he suppo ing bone in e ms o magni ude o s ess,
s ain, and s ess dis ibu ion: A ini e elemen analysis. BioMed Res. In . 2021,2021, 3087071. [C ossRe ] [PubMed]
14.
Delgado-Ruiz, R.A.; Cal o-Gui ado, J.L.; Romanos, G.E. E ec s o occlusal o ces on he pe i-implan -bone in e ace s abili y.
Pe iodon ology 2000 2019,81, 179–193. [C ossRe ]
15.
Bagegni, A.; Abou-Ayash, S.; Rücke , G.; Alga ny, A.; A , W. The in luence o p os he ic ma e ial on implan and p os he ic
su i al o implan -suppo ed ixed comple e den u es: A sys ema ic e iew and me a-analysis. J. P os hodon . Res. 2019,
63, 251–265. [C ossRe ]
Ma e ials 2025,18, 2692 18 o 20
16.
Misch, C.E.; Resnik, R.R. A ailable bone and den al implan ea men plans. In Misch’s Con empo a y Implan Den is y, 4 h ed.;
Else ie : Ams e dam, The Ne he lands, 2020; p. 415.
17.
Rues, S.; Schmi e , M.; Kappel, S.; Sonn ag, R.; K e ze , J.P.; Nado , J. E ec o bone quali y and quan i y on he p ima y s abili y
o den al implan s in a simula ed bico ical placemen . Clin. O al In es ig. 2020,25, 1265–1272. [C ossRe ] [PubMed]
18.
Kowalski, J.; Lapinska, B.; Nissan, J.; Lukomska-Szymanska, M. Fac o s In luencing Ma ginal Bone Loss a ound Den al Implan s:
A Na a i e Re iew. Coa ings 2021,11, 865. [C ossRe ]
19.
Di S e ano, D.A.; A osio, P.; Cappa è, P.; Ba bon, S.; Ghe lone, E.F. Ghe lone, S abili y o den al implan s and hickness o co ical
bone: Clinical esea ch and u u e pe spec i es. A sys ema ic e iew. Ma e ials 2021,14, 7183. [C ossRe ]
20.
Cla o , S.; Ch is ensen, B.J.; Chapple, A.G.; Block, M.S. Block, P edic ion o esidual al eola bone heigh in he pos e io maxilla
a e den al ex ac ions. J. O al Maxillo ac. Su g. 2021,80, 517–524. [C ossRe ]
21.
Toledano, M.; Fe nández-Rome o, E.; Vallecillo, C.; Toledano, R.; Oso io, M.T.; Vallecillo-Ri as, M. Sho e sus s anda d implan s
a sinus augmen ed si es: A sys ema ic e iew and me a-analysis. Clin. O al In es ig. 2022,26, 6681–6698. [C ossRe ]
22.
Pa k, S.; Pa k, J.; Kang, I.; Lee, H.; Noh, G. E ec s o assessing he bone emodeling p ocess in biomechanical ini e elemen
s abili y e alua ions o den al implan s. Compu . Me hods P og ams Biomed. 2022,221, 106852. [C ossRe ]
23.
I andous , S.; Mü ü, S. The in e play be ween bone healing and emodeling a ound den al implan s. Sci. Rep. 2020,10, 4335.
[C ossRe ] [PubMed]
24. Flanagan, D. Osseous emodeling a ound den al implan s. J. O al Implan . 2019,45, 239–246. [C ossRe ] [PubMed]
25.
Ghe de, C.; Dha ak, P.; Nimbalka , S.; Joshi, S. A comp ehensi e e iew o ac o s a ec ing a igue li e o den al implan s. Ma e .
Today P oc. 2020,43, 1117–1123. [C ossRe ]
26.
Ziaie, B.; Khalili, S.M.R. E alua ion o a igue li e o den al implan s using FEM analysis. P os hesis 2021,3, 300–313. [C ossRe ]
27. A ai, Y.; Takashima, M.; Ma suzaki, N.; Takada, S. Ma ginal bone loss in den al implan s: A li e a u e e iew o isk ac o s and
ea men s a egies o p e en ion. J. P os hodon . Res. 2024,69, 12–20. [C ossRe ]
28.
Gu en, S.S.; Cabba , F.; Gule , N. Local and sys emic ac o s associa ed wi h ma ginal bone loss a ound den al implan s: A
e ospec i e clinical s udy. Quin essence In . 2020,51, 128–141.
29.
Alemayehu, D.-B.; Jeng, Y.-R. Th ee-dimensional ini e elemen in es iga ion in o e ec s o implan h ead design and loading
a e on s ess dis ibu ion in den al implan s and aniso opic bone. Ma e ials 2021,14, 6974. [C ossRe ] [PubMed]
30.
Ishak, M.I.; Daud, R.; Ib ahim, I.; Ma , F.; Manso , N.N. Manso , Biomechanical o e loading ac o s in luencing he ailu e o
den al implan s: A e iew. In Symposium on Damage Mechanism in Ma e ials and S uc u es; Sp inge : Be lin/Heidelbe g, Ge many,
2020; pp. 127–142.
31.
Lo a o, S.T.; Bassani, R.; Sa kis-Ono e, R.; dos San os, M.B.F. In luence o di e en implan geome y in clinical longe i y and
main enance o ma ginal bone: A sys ema ic e iew. J. P os hodon . 2018,28, e713–e721. [C ossRe ]
32.
Filho, L.C.D.C.; Fao , F.; Mad uga, M.d.M.; Ma cello-Machado, R.M.; Bo din, D.; Cu y, A.A.D.B. E ec o implan mac ogeome y
on pe i-implan healing ou comes: A andomized clinical ial. Clin. O al In es ig. 2018,23, 567–575. [C ossRe ]
33.
K e e, S.; Fe ei a, I.; Valen e, M.L.d.C.; dos Reis, A.C. Rela ionship be ween den al implan mac o-design and osseoin eg a ion:
A sys ema ic e iew. O al Maxillo ac. Su g. 2022,28, 1–14. [C ossRe ] [PubMed]
34.
He e o-Climen , M.; López-Ja ana, P.; Lemos, B.F.; Gil, F.J.; Falcão, C.; Ríos-San os, J.V.; Ríos-Ca asco, B. Rele an design aspec s
o imp o e he s abili y o i anium den al implan s. Ma e ials 2020,13, 1910. [C ossRe ]
35.
Ani ua, E.; de Iba a, N.L.S.; Ma ín, I.M.; Ro aeche, L.S. In luence o den al implan diame e and bone quali y on he biomechan-
ics o single-c own es o a ion. A ini e elemen analysis. Den . J. 2021,9, 103. [C ossRe ] [PubMed]
36.
Elleuch, S.; J ad, H.; Kessen ini, A.; Wali, M.; Dammak, F. Design op imiza ion o implan geome ical cha ac e is ics enhancing
p ima y s abili y using FEA o s ess dis ibu ion a ound den al p os hesis. Compu . Me hods Biomech. Biomed. Eng. 2021,
24, 1035–1051. [C ossRe ]
37.
Büyük, F.N.; Sa an, E.; Ka pa , F. Re iew on ini e elemen analysis o den al implan s. J. Den . Implan Res. 2022,41, 50–63.
[C ossRe ]
38.
Falcinelli, C.; Valen e, F.; Vas a, M.; T aini, T. Fini e elemen analysis in implan den is y: S a e o he a and u u e di ec ions.
Den . Ma e . 2023,39, 539–556. [C ossRe ] [PubMed]
39.
Kudagi, V.; Shi akuma , S.; Talwade, P. Applica ions o ini e elemen analysis in den is y: A e iew. J. In . O al Heal h 2021,
13, 415–422. [C ossRe ]
40.
Cas illa, R.; Fo e o, L.; González-Es ada, O.A. Compa a i e s udy o he in luence o den al implan design on he s ess and
s ain dis ibu ion using he ini e elemen me hod. J. Phys. Con . Se . 2019,1159, 012016. [C ossRe ]
41.
And ee ich, S.Y.; Zu abo ich, C.D.; Mikhailo ich, A.V. The usage o he ini e elemen analysis in he design o new den al
implan sys ems. In . J. Inno . Med. 2023,1, 19–23.
42.
Lee, H.; Jo, M.; Noh, G. Biomechanical e ec s o den al implan diame e , connec ion ype, and bone densi y on mic ogap
o ma ion and a igue ailu e: A ini e elemen analysis. Compu . Me hods P og ams Biomed. 2021,200, 105863. [C ossRe ]
Ma e ials 2025,18, 2692 19 o 20
43.
Fio illo, L.; Cicciù, M.; D’amico, C.; Mauce i, R.; O e i, G.; Ce ino, G. Fini e elemen me hod and on mises in es iga ion on
bone esponse o dynamic s ess wi h a no el conical den al implan connec ion. BioMed Res. In . 2020,2020, 2976067. [C ossRe ]
[PubMed]
44.
Pamme , D. E alua ion o pos ope a i e den al implan p ima y s abili y using 3D ini e elemen analysis. Compu . Me hods
Biomech. Biomed. Eng. 2019,22, 280–287. [C ossRe ] [PubMed]
45.
Shaki , S.M.; Muhsin, S.A.; Al Ma za, R. Fini e Elemen Modelling Based S udies o Den al Implan s: Sys ema ic Re iew. J. Tech.
2022,4, 155–169. [C ossRe ]
46.
Vanaclocha, V.; A ienza, C.; Vanaclocha, A.; Peñuelas, A.; Gómez-He e o, J.; Pé ez-Ca ió, F.; Diego-Leyda, J.A.; Sáiz-Sapena, N.;
Vanaclocha, L. New Subpe ios eal Den al Implan Design wi h Fini e Elemen Analysis and Mechanical Valida ion: A Design
Valida ion S udy. Ma e ials 2025,18, 622. [C ossRe ]
47.
Cheng, Y.-C.; Lin, D.-H.; Jiang, C.-P.; Lee, S.-Y. Design imp o emen and dynamic ini e elemen analysis o no el ITI den al
implan unde dynamic chewing loads. Bio-Med. Ma e . Eng. 2015,26, S555–S561. [C ossRe ]
48.
Domme i, V.K.; P amanik, S.; Roy, S. Design o cus omized coa ed den al implan s using ini e elemen analysis. Den . Med. P obl.
2023,60, 385–392. [C ossRe ]
49.
Pa il, V.; Naik, N. A compa a i e s udy on he e ec o s ess in den al implan s uc u e using ini e elemen analysis. In . J. Mech.
P od. Eng. Res. De . 2019,9, 709–717.
50.
Ne o, J.V.C.; Celles, C.A.S.; de And ade, C.S.A.F.; A onso, C.R.M.; Nagay, B.E.; Ba ão, V.A.R. Recen ad ances and p ospec s in
β- ype i anium alloys o den al implan s applica ions. ACS Bioma e . Sci. Eng. 2024,10, 6029–6060. [C ossRe ]
51.
Mao, C.; Yu, W.; Jin, M.; Wang, Y.; Shang, X.; Lin, L.; Zeng, X.; Wang, L.; Lu, E. Mechanobiologically op imized Ti–35Nb–2Ta–3Z
imp o es load ansduc ion and enhances bone emodeling in il ed den al implan he apy. Bioac . Ma e . 2022,16, 15–26.
52.
Ale izakos, V.; Mi o , G.; Ah ens, A.; on See, C. The in luence o implan si e p epa a ion and s e iliza ion on he pe o mance
and wea o implan d ills. In . J. O al Maxillo ac. Implan 2021,36, 546–552. [C ossRe ]
53.
Nandini, N.; Kunuso h, R.; Alwala, A.M.; P akash, R.; Samp ee hi, S.; Ka ku i, S. Cylind ical Implan Ve sus Tape ed Implan : A
Compa a i e S udy. Cu eus 2022,14, e29675. [C ossRe ] [PubMed]
54.
Rugo a, S.; Abboud, M. The mal E alua ion o Bone D illing wi h a One-D ill P o ocol. Bioenginee ing 2024,11, 1022. [C ossRe ]
[PubMed]
55.
obau-Po ua, A.; González, J.E.; Rod íguez-Gue a, J.; González-Mede os, P.; Na a o, P.; de la Rosa, J.E.; Ca bonell-González,
M.; A aneda-He nández, E.; To es, Y. Biomechanical beha io o a new design o den al implan : In luence o he po osi y and
loca ion in he maxilla. J. Ma e . Res. Technol. 2024,29, 3255–3267. [C ossRe ]
56.
Robau-Po ua, A.; González, J.E.; A ancibia-Cas illo, R.; Pica do, A.; A aneda-He nández, E.; To es, Y. Design, ab ica ion,
and cha ac e iza ion o no el den al implan s wi h po osi y g adien ob ained by Selec i e Lase Mel ing. Ma e . Des. 2025,
251, 113660.
57.
Rod íguez, Y.; Ruíz, J.G.; Ruiz-Val e de, O.; Pé ez-Ál a ez, M. Simula ion o he in luence o he pla o m swi ching o a
model o den al implan on he bio-mechanics o maxilla y bones. In P oceedings o he Den al Implan s, Chicago, IL, USA,
29 No embe 2018.
58.
Pé ez-Pe ida, E.; B izuela-Velasco, A.; Chá a i-P ado, D.; Jiménez-Ga udo, A.; Sánchez-Lashe as, F.; Solabe ie a-Méndez,
E.; Diéguez-Pe ei a, M.; Fe nández-González, F.J.; Dehesa-Iba a, B.; Mon icelli, F. Biomechanical Consequences o he Elas ic
P ope ies o Den al Implan Alloys on he Suppo ing Bone: Fini e Elemen Analysis. BioMed Res. In . 2016,2016, 1850401.
[C ossRe ]
59.
Elhadad, A.A.; Rome o-Resendiz, L.; Rossi, M.; Rod íguez-Albelo, L.; Lascano, S.; A onso, C.R.; Alcudia, A.; Amigó, V.; To es,
Y. Findings and pe spec i es o
β
-Ti alloys wi h biomedical applica ions: Explo ing beyond biomechanical and bio unc ional
beha iou . J. Ma e . Res. Technol. 2024,33, 3550–3618. [C ossRe ]
60.
Pellizze , E.P.; Lemos, C.A.A.; Almeida, D.A.F.; Ba is a, V.E.D.S.; Júnio , J.F.S.; Ve i, F.R. Biomechanical analysis o di e en
implan -abu men s in e aces in di e en bone ypes: An in silico analysis. Ma e . Sci. Eng. C 2018,90, 645–650. [C ossRe ]
61.
Hussein, M.O. Biomechanical analysis o di e en implan -o e den u e loading p o ocols unde dynamic loads. J. Am. Sci. 2013,
9, 8.
62.
Himmlo á, L.; Dos álo á, T.; Káco ský, A.; Kon iˇcko á, S. In luence o implan leng h and diame e on s ess dis ibu ion: A
ini e elemen analysis. J. P os he . Den . 2004,91, 20–25. [C ossRe ]
63.
Yemineni, B.C.; Mahend a, J.; Nasina, J.; Mahend a, L.; Shi asub amanian, L.; Pe ika, S.B. E alua ion o maximum p incipal
s ess, on mises s ess, and de o ma ion on su ounding mandibula bone du ing inse ion o an implan : A h ee-dimensional
ini e elemen s udy. Cu eus 2020,12, e9430. [C ossRe ]
64.
T e o, P.H.W.; dos San os, M.B.F.; Spazzin, A.O.; Pe ei a, G.K.R.; Bacchi, A. Assessmen o s ess/s ain in den al implan s and
abu men s o al e na i e ma e ials compa ed o con en ional i anium alloy—3D non-linea ini e elemen analysis. Compu .
Me hods Biomech. Biomed. Eng. 2020,23, 372–383. [C ossRe ] [PubMed]
Ma e ials 2025,18, 2692 20 o 20
65.
Li, J.; Jansen, J.A.; Walboome s, X.F.; an den Beucken, J.J. Mechanical aspec s o den al implan s and osseoin eg a ion: A na a i e
e iew. J. Mech. Beha . Biomed. Ma e . 2020,103, 103574. [C ossRe ] [PubMed]
66.
Gao, X.; F aulob, M.; Haïa , G. Biomechanical beha iou s o he bone–implan in e ace: A e iew. J. R. Soc. In e ace 2019,
16, 20190259. [C ossRe ]
67.
Li, R.; Wu, Z.; Chen, S.; Li, X.; Wan, Q.; Xie, G.; Pei, X. Biomechanical beha io analysis o ou ypes o sho implan s wi h
di e en placemen dep hs using he ini e elemen me hod. J. P os he . Den . 2023,129, 447.e1–447.e10. [C ossRe ]
68.
Robau-Po ua, A.; Pé ez-Rod íguez, Y.; So is-Rod íguez, L.M.; Pé ez-Acos a, O.; González, J.E. The e ec o diame e , leng h and
elas ic modulus o a den al implan on s ess and s ain le els in pe i-implan bone: A 3D ini e elemen analysis. Bio-Med. Ma e .
Eng. 2020,30, 541–558. [C ossRe ]
69.
Song, K.; Wang, Z.; Lan, J.; Ma, S. Po ous s uc u e design and mechanical beha io analysis based on TPMS o cus omized oo
analogue implan . J. Mech. Beha . Biomed. Ma e . 2021,115, 104222. [C ossRe ]
70.
Ma ins, D.; Cou o, R.; Fonseca, E.M.; Ca ei as, A.R. Nume ical analysis o he mechanical s imuli ans e ed om a den al
implan o he bone. J. Compu . Appl. Res. Mech. Eng. (JCARME) 2021,11, 1–11.
71.
F os , H.M. Bone’s mechanos a : A 2003 upda e, The Ana omical eco d pa a: Disco e ies in molecula , cellula , and e olu iona y
biology: An o icial publica ion o he ame ican associa ion o ana omis s. Ana . Rec. 2003,275, 1081–1101. [C ossRe ]
72.
Baggi, L.; Cappelloni, I.; Di Gi olamo, M.; Mace i, F.; Vai o, G. The in luence o implan diame e and leng h on s ess dis ibu ion
o osseoin eg a ed implan s ela ed o c es al bone geome y: A h ee-dimensional ini e elemen analysis. J. P os he . Den . 2008,
100, 422–431. [C ossRe ]
73.
Ding, X.; Liao, S.; Zhu, X.; Zhang, X.; Zhang, L. E ec o diame e and leng h on s ess dis ibu ion o he al eola c es a ound
immedia e loading implan s. Clin. Implan Den . Rela . Res. 2009,11, 279–287. [C ossRe ]
74.
Muangsisied, S.; Chan a apanich, N.; Vee asakul, M.S.; Inglam, S. E ec o implan diame e and co ical bone hickness on
biomechanical pe o mance o sho den al implan -suppo ed dis al can ile e : A ini e elemen s udy. Eng. J. 2021,25, 175–182.
[C ossRe ]
75.
P emna h, K.; S ide i, J.; Kala a hy, N.; Naga anjani, P.; Sha mila, M.R. E alua ion o s ess dis ibu ion in bone o di e en
densi ies using di e en implan designs: A h ee-dimensional ini e elemen analysis. J. Indian P os hodon . Soc. 2012,13, 555–559.
[C ossRe ] [PubMed]
76.
Liao, S.-H.; Zhu, X.-H.; Xie, J.; Sohodeb, V.K.; Ding, X. In luence o T abecula Bone on Pe i-Implan S ess and S ain Based on
Mic o-CT Fini e Elemen Modeling o Beagle Dog. BioMed Res. In . 2016,2016, 3926941. [C ossRe ] [PubMed]
77.
Yuan, X.; Liu, Y.; Yang, Y.; Ren, M.; Luo, L.; Zheng, L.; Liu, Y. E ec o sho implan c own- o-implan a io on s ess dis ibu ion
in aniso opic bone wi h di e en osseoin eg a ion a es. BMC O al Heal h 2023,23, 683. [C ossRe ]
78.
Li, J.; Li, H.; Shi, L.; Fok, A.S.; Uce , C.; De lin, H.; Ho ne , K.; Silikas, N. A ma hema ical model o simula ing he bone
emodeling p ocess unde mechanical s imulus. Den . Ma e . 2007,23, 1073–1078. [C ossRe ]
Disclaime /Publishe ’s No e: The s a emen s, opinions and da a con ained in all publica ions a e solely hose o he indi idual
au ho (s) and con ibu o (s) and no o MDPI and/o he edi o (s). MDPI and/o he edi o (s) disclaim esponsibili y o any inju y o
people o p ope y esul ing om any ideas, me hods, ins uc ions o p oduc s e e ed o in he con en .