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Effectiveness of digital interventions to reduce school-age adolescent sexual risks: A systematic review

Abstract

Introduction: The increase in risky sexual behaviors among adolescent students has sparked alarm and has become an area of research interest. As adolescents prioritize confidentiality and accessibility, digital interventions are becoming increasingly relevant in sex education. We therefore posed the following research question: Are digital application interventions effective to prevent risky sexual behaviors in school adolescents? Design: A systematic peer review was conducted between January and December 2023 in five databases (PubMed, Web of Science, Scopus, EMBASE, and PsycINFO) without restricting for language or year of publication. Method: We included randomized control trials or quasi-experimental studies that measured the effectiveness of interventions targeting young people aged 10–19 years or their parents and developed in a school setting. Interventions aimed at young people with intellectual disabilities, learning difficulties, or any disease requiring a specific intervention were excluded. Results: The search ultimately yielded 27 studies covering a total of 18 digital interventions that demonstrated positive effects, not maintained over time, on knowledge, attitudes, and behaviors, although the latter to a lesser extent. Discussion: We have found very interesting digital interventions with effects, among others, on knowledge, attitudes, and contraceptive use in adolescents. In general, digital interventions have positive effects on knowledge and attitudes, but it is more difficult to modify behaviors with strictly digital interventions or combined with complementary face-to-face sessions or group class activities. Conclusion: We thus believe that digital interventions are adequate to reduce adolescent sexual risk behaviors, and our systematic review facilitates the implementation of these interventions by sharing existing digital interventions that have had positive effects, as well as the main characteristics a digital intervention should possess to reduce sexually risky behaviors in adolescents. Clinical relevance: Digital interventions with adolescents improve sexual behaviors and can be a valuable resource in education on this topic due to their accessibility and confidentiality, two key points for young people.

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Effectiveness of digital interventions to reduce school-age adolescent sexual risks: A systematic review

Author: Aguilar-Quesada, Ana; Sierra-Yagüe, Alba; González Cano-Caballero, María; Zafra-Agea, José Antonio; Lima Serrano, Marta
Publisher: Wiley
Year: 2025
DOI: 10.1111/jnu.13015
Source: https://idus.us.es/bitstreams/d82634c4-db39-4ab9-96ec-fbabf35a878c/download
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J Nu s Sch. 2025;57:342–353.wileyonlinelib a y.com/jou nal/jnu
Recei ed: 12 Ap il 2024
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Re ised: 17 July 2024
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Accep ed: 29 July 2024
DOI: 10.1111/jnu.13015
WORLD HEALTH
E ec i eness o digi al in e en ions o educe school- age
adolescen sexual isks: A sys ema ic e iew
Ana Aguila - Quesada RN, MSN1 | Alba Sie a- Yagüe RN, MSN2 |
Ma ía González- Cano- Caballe o RN, MSN, PhD3 | José An onio Za a- Egea RN, MSN, PhD4 |
Ma a Lima- Se ano RN, MSN, PhD5,6
This is an open access a icle unde he e ms o he C ea i e Commons A ibu ion License, which pe mi s use, dis ibu ion and ep oduc ion in any medium,
p o ided he o iginal wo k is p ope ly ci ed.
© 2024 The Au ho (s). Jou nal o Nu sing Schola ship published by Wiley Pe iodicals LLC on behal o Sigma The a Tau In e na ional.
1Hospi al Uni e si a io San Cecilio,
G anada, Spain
2Ca alan Ins i u e o Heal h, Ba celona,
Spain
3Depa men o Nu sing, Facul y o Heal h
Sciences, Uni e si y o G anada, G anada,
Spain
4Depa men o Nu sing o he Facul y o
Heal h Sciences o UMan esa, Fundació
Uni e si à ia del Bages, Uni e si y o Vic,
Cen al Uni e si y o Ca alonia, Ba celona,
Spain
5Depa men o Nu sing, School o
Nu sing, Physio he apy, and Podia y,
Uni e si y o Se ille, Se ille, Spain
6Ins i u e o Biomedicine o Se ille (IBiS),
Se illa, Spain
Co espondence
Ma ía González- Cano- Caballe o,
Depa men o Nu sing, Facul y o Heal h
Sciences, Uni e si y o G anada, G anada,
Spain.
Email: ma iagcc@ug .es
Abs ac
In oduc ion: The inc ease in isky sexual beha io s among adolescen s uden s has
spa ked ala m and has become an a ea o esea ch in e es . As adolescen s p io -
i ize con iden iali y and accessibili y, digi al in e en ions a e becoming inc easingly
ele an in sex educa ion. We he e o e posed he ollowing esea ch ques ion: A e
digi al applica ion in e en ions e ec i e o p e en isky sexual beha io s in school
adolescen s?
Design: A sys ema ic pee e iew was conduc ed be ween Janua y and Decembe
2023 in i e da abases (PubMed, Web o Science, Scopus, EMBASE, and PsycINFO)
wi hou es ic ing o language o yea o publica ion.
Me hod: We included andomized con ol ials o quasi- expe imen al s udies ha
measu ed he e ec i eness o in e en ions a ge ing young people aged 10–19 yea s
o hei pa en s and de eloped in a school se ing. In e en ions aimed a young peo-
ple wi h in ellec ual disabili ies, lea ning di icul ies, o any disease equi ing a speci ic
in e en ion we e excluded.
Resul s: The sea ch ul ima ely yielded 27 s udies co e ing a o al o 18 digi al in e -
en ions ha demons a ed posi i e e ec s, no main ained o e ime, on knowledge,
a i udes, and beha io s, al hough he la e o a lesse ex en .
Discussion: We ha e ound e y in e es ing digi al in e en ions wi h e ec s, among
o he s, on knowledge, a i udes, and con acep i e use in adolescen s. In gene al,
digi al in e en ions ha e posi i e e ec s on knowledge and a i udes, bu i is mo e
di icul o modi y beha io s wi h s ic ly digi al in e en ions o combined wi h com-
plemen a y ace- o- ace sessions o g oup class ac i i ies.
Conclusion: We hus belie e ha digi al in e en ions a e adequa e o educe adoles-
cen sexual isk beha io s, and ou sys ema ic e iew acili a es he implemen a ion
o hese in e en ions by sha ing exis ing digi al in e en ions ha ha e had posi i e
e ec s, as well as he main cha ac e is ics a digi al in e en ion should possess o
educe sexually isky beha io s in adolescen s.
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EFFECTIVENESS OF DIGITAL INTERVENTIONS TO REDUCE SCHOOL- AGE ADOLESCENT SEXUAL
RISKS: A SYSTEMATIC REVIEW
INTRODUCTION
Adolescence is a pe iod o ansi ion ha in ol es g ea physical,
psychological, social, and emo ional changes, which a y based on
se e al ac o s such as he educa ion ecei ed, he en i onmen ,
con ex , and skills, among o he s (Simanjun ak e al., 2023), and can
a ec bo h sex educa ion and sexual beha io . Inc eases in isky
sexual beha io s among adolescen s uden s—such as ha ing sexual
in e cou se a younge ages o no using condoms in hei sexual
in e cou ses (Inchley e al., 2018)—ha e spa ked ala m and become
an a ea o in e es o global public heal h esea che s, who ha e
sough inno a i e app oaches o p omo e be e heal hy sexual ou -
comes (Ha una e al., 2018). Due o he inc ease in isky beha io s,
an inc ease in sexually ansmi ed in ec ions (STIs) has been ob-
se ed in his popula ion (Wo ld Heal h O ganiza ion [WHO], 2019).
O he es ima ed 39.0 million people li ing wi h HIV wo ldwide in
2022, 2.58 million we e child en aged 0–19. Human papilloma i us
(HPV) is he mos common STI, and he e we e abou 43 million
HPV in ec ions in 2018, many among people in hei la e eens and
ea ly 20s. Chlamydia, gonococcus, and HIV a e common STIs as well
(WHO, 2021a). In addi ion o sexually ansmi ed diseases, adoles-
cen gi ls ace he possibili y o unin ended p egnancies ha may
end in abo ions, eclampsia, pue pe al endome i is, and sys emic
in ec ions, which can be dange ous o he adolescen heal h (Sully
e al., 2019).
The Uni ed Na ions has p oclaimed sexual and ep oduc i e
heal h o be a uni e sal human igh (Panchaud, 2022). Acco ding o
WHO, sexual heal h is a s a e o physical, emo ional, men al, and so-
cial well- being in ela ion o sexuali y. Sexual heal h equi es a pos-
i i e and espec ul app oach o sexuali y and sexual ela ionships,
as well as he possibili y o ha ing pleasu able and sa e sexual expe-
iences, ee o coe cion, disc imina ion, and iolence (WHO, 2024).
So, he abo e da a show ha educa ion on sexuali y and ep oduc-
ion is necessa y o equip young people wi h he knowledge, skills,
a i udes, and alues hey need o de e mine and enjoy hei sex-
uali y, physically and emo ionally, indi idually and in ela ionships.
T adi ionally, he bes se ing o sex educa ion is he school, whe e
heal h p o essionals and eache s ha e easie access o young peo-
ple (Gold a b & Liebe man, 2021). Howe e , gi en ha adolescen s
p io i ize con iden iali y and accessibili y o e eliable heal h in o -
ma ion, digi al in e en ions ha e ecen ly become mo e ele an
o sex educa ion (B ayboy e al., 2018). Digi al in e en ions—also
called In e ne - based o web- based in e en ions—a e he use
o he In e ne o acili a e he dissemina ion o heal h- ela ed
in o ma ion and o connec pa ien s o suppo (Na ional Lib a y o
Medicine, 2023). This can include ex message in e en ions, sma -
phone applica ions, and websi es. The use o digi al in e en ions is
a p omising me hod o add ess sexual and ep oduc i e heal h dis-
pa i ies among di e en g oups o adolescen s. Such in e en ions
a e also mo e easily sp ead and implemen ed and ha e highe e -
icacy and g ea e engagemen compa ed o adi ional beha io al
in e en ions (B ayboy e al., 2018).
The WHO ecommends lis ening o young people o design sus-
ainable digi al solu ions, because hey a e expe s on hei heal h
needs, he echnologies hey use, and how hey access o in o -
ma ion (WHO, 2021b). Technologies a e pa o he ou ine o ad-
olescen s, who use hem o in o ma ion seeking, communica ion,
and leisu e. Mos (95%) o eens now epo ha ing a sma phone
o access o one (Robb e al., 2019). These mobile connec ions a e,
in u n, mo i a ing mo e pe sis en online ac i i ies: 45% o eens
now say hey a e online on a nea - cons an basis. Howe e , he e is
no clea consensus abou he e ec ha social ne wo ks and online
in e en ions ha e on he li es o young people oday. Mos eens
desc ibe ha e ec as mos ly posi i e (31%) o mos ly nega i e
(24%), bu nea ly hal (45%) say ha e ec is nei he posi i e no
nega i e (Robb e al., 2019). I is hus e y impo an o ensu e good
digi al li e acy and o each young people he necessa y esou ces
o use echnology o ma e s o sexual heal h. A digi al in e en-
ion in schools could hus be a p omising solu ion o he p omo ion
o sexual heal h and he p e en ion o isky sexual beha io among
adolescen s.
Se e al li e a u e e iews ha e been published on digi al in e -
en ions o p e en isky sexual beha io in adolescen s (B ayboy
e al., 2018; Gold a b & Liebe man, 2021; Nou imand e al., 2022),
bu he e has been no s anda diza ion o in e en ions and a clea
end owa d he use o echnologies (B ayboy e al., 2018) o he
use o he school as an in e en ion se ing. These e iews p o ide
ex ensi e suppo o a b oad and comp ehensi e ea men o sex
educa ion, as well as o he e ec i eness o digi al in e en ions
(B ayboy e al., 2018; Gold a b & Liebe man, 2021; Nou imand
e al., 2022). Howe e , hese e iews included a icles wi h di e en
designs, including andomized con ol ials (RCTs), c oss- sec ional
s udies, p o ocols, expe imen al and quasi- expe imen al s udies,
and coho s ha may ha e in luenced he indings (Nou imand
e al., 2022). Fo his eason, new e iews on his subjec a e ecom-
mended o o e come hese limi a ions.
The objec i e o his sys ema ic e iew is o summa ize and e alu-
a e exis ing esea ch on digi al in e en ions o imp o e adolescen s'
Clinical ele ance: Digi al in e en ions wi h adolescen s imp o e sexual beha io s
and can be a aluable esou ce in educa ion on his opic due o hei accessibili y and
con iden iali y, wo key poin s o young people.
KEYWORDS
adolescen , heal h educa ion, in e ne - based in e en ion, sexual beha io
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EFFECTIVENESS OF DIGITAL INTERVENTIONS TO REDUCE SCHOOL- AGE ADOLESCENT SEXUAL
RISKS: A SYSTEMATIC REVIEW
knowledge, a i udes, in en ion, and beha io s ela ed o sexual isk
and how such in e en ions ha e been implemen ed. Fo u u e e-
sea che s, i is in ended o be use ul o gene a e e ec i e online
in e en ions on sexuali y in schools. This e iew in es iga ed he
ollowing esea ch ques ion: A e digi al applica ion in e en ions e -
ec i e o p e en isky sexual beha io s in school- age adolescen s?
METHODS
To achie e he esea ch objec i es, a sys ema ic e iew was ca ied
ou be ween Janua y and Decembe 2023 in acco dance wi h he
PRISMA Decla a ion. This sys ema ic e iew has been egis e ed
wi h PROSPERO unde ID CRD42022306728. PROSPERO is an in-
e na ional da abase o p ospec i ely egis e ed sys ema ic e iews
in heal h and social ca e, wel a e, public heal h, educa ion, c ime,
jus ice, and in e na ional de elopmen and is unded by he Na ional
Ins i u e o Heal h Resea ch (NIHR). PROSPERO aims o p o ide
a comp ehensi e lis o sys ema ic e iews egis e ed a incep ion
o help a oid duplica ion and educe he oppo uni y o epo ing
bias by allowing compa ison o he comple ed e iew wi h wha was
planned in he p o ocol.
Eligibili y c i e ia
To be included, a icles should be RCTs o quasi- expe imen al
ials. The e we e no es ic ions on language and yea o
publica ion. A icles should include adolescen s (10–19 yea s
old) who ecei ed digi al applica ion in e en ions, in e en ions
de eloped in any school, and an e alua ion o he e ec i eness o
he digi al in e en ion. We decided ha he digi al in e en ions
would be de eloped a schools o uni y as much as possible he
cha ac e is ics and con ex o he popula ion and he de elopmen
and cha ac e is ics o he in e en ions. Ou sc eening eam
excluded an a icle i i was a case- con olled ial, coho s udy,
case epo , case se ies, non- o iginal esea ch, seconda y epo ,
commen a y, edi o ial, e iew, a s udy ha did no epo ou comes
ela ed o sexual p e en ion, a s udy weak me hodological quali y,
o a s udy ha included adolescen s wi h in ellec ual disabili y,
lea ning disabili ies, ano he disabili y, isk, o any illness ha
equi ed a speci ic in e en ion.
In o ma ion sou ces
The sea ch was conduc ed independen ly by wo esea che s in i e
elec onic da abases (PubMed, Web o Science, Scopus, EMBASE,
and PsycINFO). We also manually sea ched he e e ence lis o in-
cluded s udies o iden i y po en ially ele an s udies.
Resea ch s a egy
To selec he keywo ds, an ini ial sea ch was ca ied ou in di e en
e iew pape s wi h a simila subjec ma e o ob ain a be e o e iew
o he opic o be add essed and o ob ain all he essen ial in o ma ion
o his e iew. A specialized lib a ian was also consul ed. The sea ch
s a egy was elabo a ed ollowing he popula ion, in e en ion/expo-
su e, compa a o , ou come, ime, and s udy design (PICOTS) s uc u e
as isualized in Table 1 and he e iew ques ion was: “A e digi al ap-
plica ion in e en ions e ec i e o p e en isky sexual beha io s in
school- age adolescen s?” The ollowing sea ch s a egy was used:
(Adolescen OR s uden OR een OR school- age OR mino ) AND (ap-
plica ion OR so wa e OR de ice OR “mobile applica ion” OR “mobile
app” OR m- heal h OR e- heal h OR “in e ne based” OR “web based”
OR “Compu e - assis ed ins uc ion” OR “Educa ional echnology”
OR online) AND (“sexual beha io ” OR “sexual heal h” OR “STD” OR
“sexually ansmi ed diseases” OR “sexual and ep oduc i e heal h”
OR “HIV” OR “p egnancy, unwan ed” OR “sex o enses”) AND (in e -
en ion OR “sex educa ion” OR “heal h educa ion” OR p og am OR
p e en ion OR “heal h p omo ion”). The e we e no es ic ions on lan-
guage, yea o publica ion, o a icle ype. The sea ch s a egy adap ed
o he di e en da abases can be ound in Table S1.
Selec ion p ocess and da a collec ion
All sea ch esul s we e impo ed in o a Google sp eadshee o
sc een i le, au ho /s, and bibliog aphic e e ence. Two e iewe s
TABLE 1 Popula ion, in e en ion/exposu e, compa a o , ou come, ime, and s udy design (PICOTS) c i e ia.
PICOTS c i e ia
Popula ion Adolescen s (10–19- yea - olds) in school. Any social, economic, and cul u al class
In e en ion/Exposu e Digi al in e en ions o p e en isky sexual beha io s in adolescen s using web, applica ion mobile, online p og am,
e c.
Compa a o Habi ual me hodology educa ional in e en ion o p e en isky a ec i e- sexual beha io s in adolescen s o no
in e en ion
Ou come P e en ion o isky sexual beha io s in adolescen s and hei measu e o e ec s: condom use, numbe o pos coi al
con acep i es, numbe o unwan ed p egnancies, and numbe o induced abo ions and sexually ansmi ed diseases
Time No applicable
S udy design Randomized con olled ials (RCTs) o quasi- expe imen al ials
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EFFECTIVENESS OF DIGITAL INTERVENTIONS TO REDUCE SCHOOL- AGE ADOLESCENT SEXUAL
RISKS: A SYSTEMATIC REVIEW
selec ed s udies in wo di e en ounds. Fi s , bo h e iewe s
ead he i le and abs ac and so ed by inclusion o exclusion
c i e ia. Duplica e a icles we e emo ed manually. Second,
he included da a a icles ex ac ed independen ly by he wo
e iewe s we e impo ed in o an online Google sp eadshee in a
s anda dized o de . Bo h e iewe s ag eed on he e iew o he
a icles and all disc epancies and disag eemen s we e discussed
and esol ed by e iewing he inclusion o exclusion c i e ia and
eaching a consensus o asking o hi d e iewe . Finally, he whole
p ocess was alida ed by a senio esea ch membe . This sc eening
and da a ex ac ion p ocedu e is ep esen ed h ough he PRISMA
low diag am in Figu e 1.
Da a i ems and syn hesis me hods
Da a ex ac ed om he included a icles we e collec ed in h ee
s anda dized ables o eam consensus. These ables displayed he
in o ma ion by p ojec , because mo e han one pape o en e e ed
o he same p ojec . The i s able showed s udy cha ac e is ics,
design, coun y o s udy, popula ion, sample, and ollow- up, ou comes
included, and main e ec s o he in e en ion (only hose wi h
p < 0.05). When possible, Cohen's d was calcula ed; we conside ed
alues o 0.2 low, 0.5 mode a e, and 0.8 la ge e ec s. When o e ed,
we used he odds a io (1.50 low e ec , 3.50 mode a e, and 9.00
la ge e ec ). Howe e , gi en he he e ogenei y o he s udies wi h
espec o in e en ions, pa icipan s, and ou come measu es, we
did no calcula e pooled e ec sizes.
The second able summa ized he posi i e o nega i e e ec s
o he in e en ions on p ima y ou comes (sexual in e cou se and
con acep i e use) and seconda y ou comes (knowledge and a i-
udes) in a pe iod o less han 6 mon hs and in a pe iod longe han
6 mon hs. The hi d able cap u ed in e en ion ea u es such as se -
ing, heo y, objec i e, numbe , equency and du a ion o sessions,
acili a o s, esou ces, and implemen a ion. Any missing and unclea
in o ma ion was desc ibed as “no da a” in he ables.
Bias assessmen
Me hodological quali y was a ed using he Quali y Assessmen
Tool o Quan i a i e S udies de eloped by he E ec i e Public
Heal h P ac ice P ojec (EPHHP). The quali y assessmen i ems
we e selec ion bias, s udy design, con ounde s, blinding, da a
collec ion me hods, and wi hd awal/d opou (EPHHP, 2022). Bo h
e iewe s we e ained in he use o s udy- a ing ins umen s.
FIGURE 1 Flowcha o he selec ion o a icles o he sys ema ic e iew.
Reco ds iden i ied h ough da abase (n = 9060)
PubMed (n = 2579)
PsycINFO (n = 972)
Web o Science (n = 860)
EMBASE (n = 558)
Scopus (n = 4091)
Reco ds om g ay li e a u e (n = 0)
Reco ds om o wa d and backwa d e e ence
sc eening (n=1007)
Sc eening
Included Eligibili y Iden i ica ion
Reco ds a e duplica es emo ed
(n =6520)
Selec e e ences a e eading i le and
abs ac (n = 172)
Full- ex e e ences assessed o eligibili y
(n = 172)
Full- ex a icles excluded (n =145),
due o:
Me hodological quali y weak
No ela ed o in e en ion
No a RCT o quasi-
expe imen al
The e ec i eness o he
in e en ion no e alua ed
No adolescen s (10–19)
No in a school se ing
S udies included
(n=27)
Reco ds excluded
(n = 3547)
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EFFECTIVENESS OF DIGITAL INTERVENTIONS TO REDUCE SCHOOL- AGE ADOLESCENT SEXUAL
RISKS: A SYSTEMATIC REVIEW
We sco ed each i em wi h “s ong”, “mode a e” and “weak”
depending on he answe s o di e en ques ions ha desc ibes
Quali y Assessmen Tool o Quan i a i e S udies Dic iona y.
Finally, we classi ied a icles as “s ong”, “mode a e”, and “weak”.
A hi d e iewe econciled any disag eemen be ween he main
esea che s.
E ec measu es
The p incipal ou come was p e en ion o isky sexual beha io s in
adolescen s whose measu ed e ec s we e sexual in e cou se and
con acep i e use as p ima y ou comes and knowledge and a i-
udes as seconda y ou comes.
RESULTS
As can be seen in Figu e 1, he li e a u e sea ch in he a ious
da abases yielded 9060 eco ds (2579 PubMed, 972 PsycINFO,
860 Web o Science, 558 EMBASE, and 4091 Scopus) and 1007
eco ds om he bibliog aphies o he a icles included. We so ed
he iden i ied publica ions by i le and ound ha he e we e 3547
duplica es. A e he emo al o duplica es, he emaining e-
co ds we e il e ed in acco dance wi h he inclusion and exclusion
c i e ia by i le and abs ac . Examining he i les and abs ac s
esul ed in 172 eligible eco ds. The ull ex s o he emaining e-
co ds we e subsequen ly examined. S udies ha came om he
e e ence lis s o he included a icles we e examined. A o al o
27 publica ions we e ul ima ely conside ed eligible and e ained
o he e iew.
The da es o he publica ions o he 27 s udies included in
his sys ema ic e iew anged om 1987 o p esen ; howe e ,
mos we e published a e 2017. The p ojec s we e de eloped
mainly in he Uni ed S a es, wi h o he si es in Pue o Rico (Va as-
Díaz e al., 2019), Mexico (Cas illo- A cos e al., 2016; Doubo a
e al., 2017), B azil (Halpe n e al., 2008), China (Hu e al., 2023;
Jin e al., 2021), Malaysia (Nik Fa id e al., 2018), Ko ea (Jeong
e al., 2017), Uganda (Yba a e al., 2013, 2015), and Kenya (Halpe n
e al., 2008). Two o he p ojec s did no de ine he loca ion o he in-
e en ion (Fiellin e al., 2017; Robe o, Zimme man, Ca lyle, Abne ,
Cupp, e al., 2007).
Me hodological ea u es
The me hodological ea u es o he s udies a e shown in Table S2.
S udy design
Rega ding he s udy design, all we e clus e RCTs excep o i e
a icles, which we e quasi- expe imen al (Cas illo- A cos e al., 2016;
Halpe n e al., 2008; Jeong e al., 2017; Kann, 1987; Robe o,
Zimme man, Ca lyle, & Abne , 2007), and one ield ial (Doubo a
e al., 2017). Mos o he publica ions wo ked wi h a con ol g oup
and an in e en ion g oup, excep o h ee publica ions ha
used wo expe imen al g oups and one con ol g oup (Ma kham
e al., 2012; Mu y e al., 2018, 2019), one publica ion ha used an
expe imen al g oup and wo con ol g oups (Kann, 1987), and one
publica ion ha wo ked wi h wo expe imen al g oups and wo con-
ol g oups (Halpe n e al., 2008).
Finally, se en s udies used a p e es and pos es mea-
su e (Cas illo- A cos e al., 2016; Halpe n e al., 2008; Nik
Fa id e al., 2018; Robe o, Zimme man, Ca lyle, Abne , Cupp,
e al., 2007; Scull e al., 2018; To ole o e al., 2010; Widman
e al., 2020), one s udy used a p e es and 3- mon h- ollow- up
measu es (Raghupa hy e al., 2013), ano he s udy used a p e es
and 10- week- ollow- up measu e (Robe o, Zimme man, Ca lyle, &
Abne , 2007), wo s udies used a p e es and 6- mon h- ollow- up
(Mu y e al., 2018, 2019), and one s udy used a p e es and
12- mon h- ollow- up measu e (Peskin e al., 2015) wi hou an im-
media e pos es . The es o he s udies used mo e han wo mea-
su es o e ec s.
Quali y assessmen
O he 27 a icles included in he sys ema ic e iew, 13 we e classi-
ied as “s ong” in me hodological quali y and 14 as “mode a e”. Fou
publica ions (Chong e al., 2013; Ha una e al., 2019, 2021; Ligh oo
e al., 2007), ha we e o iginally included in he sys ema ic e iew
because hey me he inclusion c i e ia, we e emo ed om he e-
iew because hei me hodological quali y was “weak”, and he e-
sea ch eam decided o exclude i o ob ain highe quali y esul s.
Pa icipan s
Mos o he a icles included did no p o ide comple e in o ma ion
abou hei pa icipan s, which made i di icul o d aw a clea de-
mog aphic p o ile. In he 27 included a icles, he pa icipan s we e
adolescen s and in h ee o hem pa en s we e also included (Mu y
e al., 2018, 2019; Va as- Díaz e al., 2019).
The pa icipan s we e mos ly en olled in schools whe e digi al
in e en ions we e ca ied ou . O he se ings included an u ban
educa ional ins i u ion (Cas illo- A cos e al., 2016), a communi y o -
ganiza ion (Va as- Díaz e al., 2019), and u ban a e - school and sum-
me camp p og ams (Fiellin e al., 2017). The s udies whose sample
we e he pa en s o adolescen s we e also de eloped in schools
(Mu y e al., 2018, 2019; Va as- Díaz e al., 2019).
Rega ding gende , mos o he in e en ions we e aimed a bo h
boys and gi ls. Howe e , he e was a g ea e endency o gi ls o
pa icipa e. Howe e , we ound ou s udies in which he p opo ion
o boys in he s udy popula ion was highe (Fiellin e al., 2017; Nik
Fa id e al., 2018; Yba a e al., 2013, 2015) and wo s udies wi h an
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EFFECTIVENESS OF DIGITAL INTERVENTIONS TO REDUCE SCHOOL- AGE ADOLESCENT SEXUAL
RISKS: A SYSTEMATIC REVIEW
equal p opo ion o boys and gi ls (Jin e al., 2021; Scull e al., 2018).
Ano he s udy had wo s udy g oups in which one g oup (B azil) had
a highe p opo ion o gi ls and he o he g oup (Kenya) had a highe
p opo ion o boys (Halpe n e al., 2008). The e was one s udy ha
did no desc ibe he gende o i s pa icipan s (Po e e al., 2016).
Mos s udies calcula ed he mean age and s anda d de ia ion o
hei sample, luc ua ing be ween 12.09/0.79 (Jin e al., 2021) and
16.25/0.76 (Widman e al., 2020), excep o he s udy whose in e -
en ion was de eloped by pa en s whose mean age and s anda d
de ia ion was 42.5/8.25 (Va as- Díaz e al., 2019). Th ee s udies did
no make his calcula ion and included hei sample in age g oups,
om 12 yea s old (Kann, 1987; Nik Fa id e al., 2018) o 19 yea s old
(Kann, 1987). The e we e wo s udies ha did no p o ide his in o -
ma ion (Jeong e al., 2017; Po e e al., 2016).
When aken oge he , he size o he samples o he 27 s udies
anged om 88 (Jeong e al., 2017) o 3244 (Po e e al., 2016) pa -
icipan s, wi h a mean o 751.071 pa icipan s (SD = 786.979).
The e en ion a e o he in e en ions included in he sys ema ic
e iew was abo e 70%, excep in wo s udies (Robe o, Zimme man,
Ca lyle, & Abne , 2007; Robe o, Zimme man, Ca lyle, Abne , Cupp,
e al., 2007) whe e hese da a we e no desc ibed, ano he s udy
whe e he e en ion a e was 69.40% (To ole o e al., 2010), and an-
o he s udy which di ided i s sample in o wo g oups, one o which
achie ed a e en ion a e o 77% (B azil) and he o he 51% (Kenya)
(Halpe n e al., 2008).
In e en ion cha ac e is ics
In e en ion goal
Table S3 summa izes he cha ac e is ics o he in e en ions ob-
ained in he sys ema ic e iew. F om he 27 publica ions included,
18 digi al in e en ions we e ex ac ed. All digi al in e en ions in
ou sys ema ic e iew sough o imp o e adolescen sexual heal h.
Mos o hem achie ed his goal by inc easing sexual knowledge,
inc easing con acep i e use, and imp o ing adolescen sexual a -
i udes. Th ee in e en ions aimed o imp o e adolescen sexual
heal h by delaying sexual ini ia ion (Ma kham e al., 2012; Peskin
e al., 2015, 2019; Po e e al., 2016; To ole o e al., 2010), one
in e en ion aimed o imp o e media li e acy educa ion o im-
p o e adolescen sexual heal h (Scull e al., 2018, 2022), and wo
in e en ions aimed o imp o e adolescen communica ion wi h
pa en s (Mu y e al., 2018, 2019) o in e pe sonal communica ion
(Kann, 1987).
In e en ion acili a o s
All bu h ee in e en ions (Halpe n e al., 2008;Nik Fa id e al., 2018;
Widman e al., 2018, 2020) had acili a o s who de eloped he in e -
en ion and helped he adolescen s ca y i ou . These acili a o s
we e ei he school eache s wi h p io aining, membe s o he e-
sea ch eam, a membe o he heal h ca e eam, o echnology in e -
en ion assis an s o acili a o aine s speci ically chosen o he
in e en ion.
In e en ion s a egies
Mos o he in e en ions we e digi al, bu he e we e h ee s udies
ha used websi e and ace- o- ace sessions in he school (Cas illo-
A cos e al., 2016; Doubo a e al., 2017; Jeong e al., 2017), and
ou s udies used compu e - based ac i i ies and g oup- based class-
oom ac i i ies (Ma kham e al., 2012; Peskin e al., 2019; Po e
e al., 2016; To ole o e al., 2010).
The me hodologies used in he di e en in e en ions we e
mainly ideos (Hu e al., 2023; Jin e al., 2021; Nik Fa id e al., 2018;
Peskin e al., 2015; Raghupa hy e al., 2013; Va as- Díaz e al., 2019;
Widman e al., 2018, 2020; Yba a e al., 2013, 2015), i ual ole-
playing (Doubo a e al., 2017; Fiellin e al., 2017; Mu y e al., 2018,
2019; Peskin e al., 2015; Raghupa hy e al., 2013), games (Doubo a
e al., 2017; Fiellin e al., 2017; Widman e al., 2018, 2020), o quizzes
(Peskin e al., 2015; Raghupa hy e al., 2013; Widman e al., 2018,
2020). Fi e s udies did no p o ide de ails abou which me hodology
was used in hei in e en ions (Cas illo- A cos e al., 2016; Halpe n
e al., 2008; Kann, 1987; Mu y e al., 2018, 2019; Scull e al., 2018,
2022).
Theo ical amewo k
Mos in e en ions we e based on heo e ical models o beha io
change— ha is, social cogni i e heo y (Ma kham e al., 2012; Peskin
e al., 2019; Po e e al., 2016; To ole o e al., 2010; Va as- Díaz
e al., 2019), heo y o planned beha io (Scull e al., 2018, 2022;
Va as- Díaz e al., 2019), heo ies o easoned ac ion and planned
beha io (Scull e al., 2018, 2022; Va as- Díaz e al., 2019; Widman
e al., 2018, 2020), o he in o ma ion- mo i a ion- beha io al skills
model (Peskin e al., 2015; Yba a e al., 2013, 2015) among o he s.
Se en s udies did no desc ibe he heo e ical model o hei in e -
en ion heo e ical model (Fiellin e al., 2017; Halpe n e al., 2008;
Hu e al., 2023; Jin e al., 2021; Kann, 1987; Nik Fa id e al., 2018;
Raghupa hy e al., 2013).
In e en ion sessions
The e was a mean o 8.51 digi al sessions in he in e en ion
ac oss s udies (SD = 7.12) and a mode is six sessions (Cas illo-
A cos e al., 2016; Halpe n e al., 2008; Mu y e al., 2018, 2019;
Raghupa hy e al., 2013; Va as- Díaz e al., 2019; Yba a e al., 2013,
2015). The sho es in e en ions had 1 digi al session (Nik Fa id
e al., 2018; Widman e al., 2018, 2020) and he longes in e en-
ion has 24 digi al sessions (Ma kham e al., 2012; Peskin e al., 2019;
Po e e al., 2016; To ole o e al., 2010).
The du a ion o he sessions o he in e en ions anged be ween
15 and 90 min, wi h a mean o 49.21 (SD = 19.58). The e was one
s udy ha did no say how long he digi al sessions las ed, and his
was omi ed om he calcula ion o he mean (Halpe n e al., 2008).
In e en ion con en s
The con en s o he sessions o he di e en in e en ions a e
shown in Table S3. Main con en s o sessions we e knowledge abou
HIV/STI, p egnancy and con acep ion, sexual skills and s a egies o
imp o e communica ion.
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EFFECTIVENESS OF DIGITAL INTERVENTIONS TO REDUCE SCHOOL- AGE ADOLESCENT SEXUAL
RISKS: A SYSTEMATIC REVIEW
Main e ec s
Signi ican e ec s (p < 0.05) a e shown in Table 2 and Table S2. All
s udies showed some posi i e e ec on adolescen sexual heal h,
ei he in e ms o sexual knowledge, sexual a i ude, o sexual be-
ha io such as con acep i e use o heal hie sexual in e cou se
compa ed o ecei ing no sexual in e en ion o ecei ing he usual
sexual in e en ion om hei school. Mos in e en ions ha aimed
o imp o e sexual heal h educa ion in adolescen s ound low o
mode a e e ec s. The e we e ou publica ions ha ound la ge e -
ec s o seconda y ou comes, wi h d = 4.78 in HIV/sexually ans-
mi ed disease (STD) knowledge (Widman e al., 2018); d = 1.27 in
HIV/STD knowledge (Widman e al., 2020), d = 1.16 in sexual knowl-
edge (Hu e al., 2023), d = 1.38 in STI knowledge (Jeong e al., 2017);
and d = 0.90 in sexual knowledge (Robe o e al., 2008).
Focusing on he e alua ion ime amewo k, om s udies ha as-
sess p ima y sexual ou comes, eigh s udies showed posi i e e ec s
on sexual in e cou se (Ma kham e al., 2012; Peskin e al., 2019;
Raghupa hy e al., 2013; Robe o e al., 2008; Robe o, Zimme man,
Ca lyle, & Abne , 2007; Robe o, Zimme man, Ca lyle, Abne , Cupp,
e al., 2007; To ole o e al., 2010; Yba a e al., 2013), o which only
wo had such e ec s a 6 mon hs (Ma kham e al., 2012; To ole o
e al., 2010). These e ec s a sho ime we e low, anging om
d = 0.11 (Robe o, Zimme man, Ca lyle, & Abne , 2007) o d = 0.3
(Raghupa hy e al., 2013).
Rega ding concep i e use, 11 s udies (Jeong e al., 2017;
Ma kham e al., 2012; Peskin e al., 2015, 2019; Robe o e al., 2008;
Scull e al., 2018; To ole o e al., 2010; Widman e al., 2018, 2020;
Yba a e al., 2013, 2015) demons a ed low posi i e e ec s wi h
Cohen's d be ween d = 0.20 (Robe o e al., 2008) and d = 0.43
(Widman e al., 2018). Fi e s udies main ained hese e ec s o e
ime up o 6 mon hs (Jeong e al., 2017; Ma kham e al., 2012; Peskin
e al., 2015; Widman e al., 2018; Yba a e al., 2015). Addi ionally,
one s udy did no show signi ican da a be o e 6 mon hs bu showed
posi i e e ec s a 6 mon hs (Doubo a e al., 2017). Finally, and
one s udy showed nega i e e ec s on con acep i e use (Halpe n
e al., 2008).
Rega ding seconda y ou comes, 21 s udies ound ha sexual
knowledge was imp o ed by he digi al in e en ion (Cas illo- A cos
e al., 2016; Doubo a e al., 2017; Fiellin e al., 2017; Hu e al., 2023;
Jeong e al., 2017; Jin e al., 2021; Kann, 1987; Ma kham e al., 2012;
Nik Fa id e al., 2018; Peskin e al., 2015, 2019; Po e e al., 2016;
Raghupa hy e al., 2013; Robe o e al., 2008; Robe o, Zimme man,
Ca lyle, & Abne , 2007; Robe o, Zimme man, Ca lyle, Abne ,
Cupp, e al., 2007; Scull e al., 2022; To ole o e al., 2010; Widman
e al., 2018, 2020; Yba a e al., 2015), wi h 11 o hese s udies main-
aining he imp o emen o e ime (Doubo a e al., 2017; Fiellin
e al., 2017; Hu e al., 2023; Jeong e al., 2017; Ma kham e al., 2012;
Peskin e al., 2015, 2019; Po e e al., 2016; To ole o e al., 2010;
Widman e al., 2018; Yba a e al., 2015). A s udy showed ha he
le el o sexual knowledge d opped a 6 mon hs (Jin e al., 2021).
These posi i e e ec s we e di ided in o se en s udies ha had a
low e ec wi h Cohen's d be ween d = 0.13 (Robe o, Zimme man,
Ca lyle, Abne , Cupp, e al., 2007) and d = 0.39 (Cas illo- A cos
e al., 2016), one s udy wi h mode a e e ec s (d = 0.61; Robe o,
Zimme man, Ca lyle, & Abne , 2007) and i e s udies wi h la ge e -
ec s on knowledge whose Cohen's d was be ween d = 0.90 (Robe o
e al., 2008) and d = 4.78 (Widman e al., 2018). The emaining s ud-
ies did no gi e a Cohen's d.
Rega ding sexual a i udes, 7 ele en demons a ed posi i e e -
ec s (Doubo a e al., 2017; Fiellin e al., 2016; Hu e al., 2023; Jin
e al., 2021; Kann, 1987; Robe o e al., 2008; Robe o, Zimme man,
Ca lyle, & Abne , 2007; Robe o, Zimme man, Ca lyle, Abne , Cupp,
e al., 2007; Widman e al., 2018, 2020; Yba a e al., 2015). These
e ec s we e, in gene al, mode a e wi h Cohen's d be ween d = 0.55
(Widman e al., 2020) and d = 0.78 (Widman e al., 2018). They we e
main ained o e ime, excep o one a icle in which he posi i e
e ec s dec eased (Jin e al., 2021) and ano he in which long- e m
e ec s we e no desc ibed (Widman e al., 2020).
In e en ion s a egy
The in e en ions ha we e exclusi ely digi al showed a g ea e
inc ease in sexual knowledge (Hu e al., 2023; Jin e al., 2021;
Kann, 1987; Nik Fa id e al., 2018; Peskin e al., 2015; Raghupa hy
e al., 2013; Robe o, Zimme man, Ca lyle, & Abne , 2007; Robe o,
Zimme man, Ca lyle, Abne , Cupp, e al., 2007; Widman e al., 2018,
2020; Yba a e al., 2013, 2015), sexual a i ude (Halpe n e al., 2008;
Hu e al., 2023; Jin e al., 2021; Kann, 1987; Raghupa hy e al., 2013;
Robe o e al., 2008; Robe o, Zimme man, Ca lyle, & Abne , 2007;
Robe o, Zimme man, Ca lyle, Abne , Cupp, e al., 2007; Widman
e al., 2018, 2020; Yba a e al., 2013, 2015), sexual communica-
ion (Widman e al., 2018, 2020), and sel - e icacy/e icacy (Halpe n
e al., 2008; Peskin e al., 2015; Robe o e al., 2008; Robe o,
Zimme man, Ca lyle, & Abne , 2007; Robe o, Zimme man, Ca lyle,
Abne , Cupp, e al., 2007). Howe e , sexual beha io was no modi-
ied by he in e en ion, excep in one case (Kann, 1987). The a i-
cles ha measu ed esul s o e a pe iod o 6 mon hs showed hese
esul s we e no sus ained o e ime (Hu e al., 2023; Jin e al., 2021;
Raghupa hy e al., 2013; Widman e al., 2018, 2020).
Fi e in e en ions combined ace- o- ace sessions wi h dig-
i al sessions (Cas illo- A cos e al., 2016; Doubo a e al., 2017;
Jeong e al., 2017; Ma kham e al., 2012; Peskin e al., 2019; Po e
e al., 2016; To ole o e al., 2010) and hei e ec s we e gene ally
posi i e. In less han 6 mon hs, he e was an imp o emen in sex-
ual knowledge (Cas illo- A cos e al., 2016; Doubo a e al., 2017;
Jeong e al., 2017; Peskin e al., 2019; Po e e al., 2016; To ole o
e al., 2010), sel - e icacy (Jeong e al., 2017; Peskin e al., 2019;
Po e e al., 2016; To ole o e al., 2010), sexual a i ude (Doubo a
e al., 2017; Ma kham e al., 2012), and con acep i e use (Doubo a
e al., 2017; Jeong e al., 2017; Ma kham e al., 2012; Peskin
e al., 2019; Po e e al., 2016; To ole o e al., 2010), and in
mo e han 6 mon hs, he e we e posi i e e ec s in con acep i e
use (Jeong e al., 2017; Ma kham e al., 2012), sexual knowledge
(Jeong e al., 2017; Ma kham e al., 2012; Peskin e al., 2019; Po e
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EFFECTIVENESS OF DIGITAL INTERVENTIONS TO REDUCE SCHOOL- AGE ADOLESCENT SEXUAL
RISKS: A SYSTEMATIC REVIEW
TABLE 2 Ou comes e ec s.
In e en ion Au ho /s and yea
P ima y ou come Seconda y ou come
Sexual in e cou se Con acep i e use Knowledge A i udes
<6 mon hs ≥6 mon hs <6 mon hs ≥6 mon hs <6 mon hs ≥6 mon hs <6 mon hs ≥6 mon hs
“You and Me” Hu e al. (2023)NS NS NS NS + + + +
Jin e al. (2021)ND ND ND ND ++↓ +−
“Media Awa e” Scull e al. (2022)ND ND ND ND +ND ND ND
Scull e al. (2018)ND ND +ND ND ND ND ND
“HEART” Widman e al. (2020)ND ND +ND +ND +ND
Widman e al. (2018)ND ND + + + + + +
“Cuídalos” Va as- Díaz e al. (2019)ND ND ND ND ND ND ND ND
“Pa hways o A ican Ame ican Success”
(PAAS)
Mu y e al., 2019 ND ND ND ND ND ND ND ND
Mu y e al. (2018)ND ND ND ND ND ND ND ND
“Malaysian Ca e o Adolescen P ojec ”
(MyCAP)
Nik Fa id e al. (2018)ND ND ND ND +ND NS ND
“I 's You Game” (IYG) Peskin e al. (2019)+NS +NS + + NS NS
Po e e al. (2016)NS −NS NS + + NS NS
To ole o e al. (2010)+++NS + + ND ND
“IYG- Tech” Peskin e al. (2015)NS NS + + + + ND ND
Sma phone app Jeong e al. (2017)ND ND + + + + ND ND
In e ne - based educa ional in e en ion Doubo a e al. (2017)ND ND NS + + + + +
“PlayFo wa d” Fiellin e al. (2017)NS NS ND ND + + + +
“Connec ” Cas illo- A cos e al. (2016)ND ND ND ND +ND ND ND
“Cybe Senga” Yba a e al. (2015)ND ND + + + + + +
Yba a e al. (2013)+NS +NS ND ND ND ND
“Abs inence and Con acep ion Educa ion
S o ehouse”: ACES
Raghupa hy e al. (2013)+ND ND ND +ND ND ND
“Risk a oidance” (RA) and “Risk educ ion”
(RR)
Ma kham e al. (2012)+ + + + + + ND ND
“Teen Web” Halpe n e al. (2008)ND ND −ND −ND ND ND
Compu e - and In e ne - based in e en ion Robe o e al. (2008)+ND +ND +ND +ND
Robe o, Zimme man, Ca lyle,
and Abne (2007)
+ND NS ND +ND +ND
Robe o, Zimme man, Ca lyle,
and Abne (2007)
+ND NS ND +ND +ND
“CAI” Kann (1987)ND ND ND ND +ND +ND
Abb e i ions: ND, no da a; NS, no signi ican ; +, posi i e signi ican e ec s; −, nega i e signi ican e ec s.
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EFFECTIVENESS OF DIGITAL INTERVENTIONS TO REDUCE SCHOOL- AGE ADOLESCENT SEXUAL
RISKS: A SYSTEMATIC REVIEW
e al., 2016), and sexual in e cou se (Ma kham e al., 2012; To ole o
e al., 2010). Be e esul s we e ob ained i he in e en ion was
comple ed (Doubo a e al., 2017).
Pa icipan s and exposu e
Digi al in e en ions ha ocused on adolescen s bu also on hei
pa en s (Mu y e al., 2018, 2019; Va as- Díaz e al., 2019) showed
imp o ed communica ion be ween hem and, he e o e, in he
sexual heal h o he adolescen s. The e we e also di e ences be-
ween hose adolescen s who ecei ed he ull digi al in e en ion
(“ ull exposu e”: 13 lessons) and hose who did no ecei e he ull
exposu e (“no exposu e”: 0 lessons, “low exposu e”: 1–4 lessons,
“mid- exposu e”: 5–8 lessons and “high exposu e”: 9–12 lessons),
wi h he inding ha “ ull exposu e” and “mid- exposu e” s uden s
we e less likely han “low exposu e” s uden s o ini ia e sex (Peskin
e al., 2015). Be e esul s we e also seen in hose in e en ions
ha included boos e sessions as opposed o hose in e en ions
ha only p o ided he main sessions (Robe o e al., 2008; Robe o,
Zimme man, Ca lyle, & Abne , 2007; Robe o, Zimme man, Ca lyle,
Abne , Cupp, e al., 2007; Yba a e al., 2013, 2015). One digi al
in e en ion ocused on imp o ing adolescen media li e acy suc-
ceeded in inc easing sexual knowledge and media and sexual heal h,
bu did no in luence communica ion (Scull e al., 2018, 2022).
Ano he digi al in e en ion was a ideo game ha imp o ed sexual
knowledge and a i udes, bu hese imp o emen s we e no sus-
ained o e ime, no did hey change pa icipan s' sexual beha io s
(Fiellin e al., 2017).
DISCUSSION
This sys ema ic e iew summa izes exis ing digi al in e en ions o
educe sexual isk beha io s and hus imp o e adolescen s' sexual
heal h. We ha e ound e y in e es ing digi al in e en ions wi h
e ec s, among o he s, on knowledge, a i udes, and con acep i e
use in adolescen s. In gene al, digi al in e en ions ha e posi i e
e ec s on knowledge and a i udes, bu i is mo e di icul o
modi y beha io s wi h s ic ly digi al in e en ions o combined
wi h complemen a y ace- o- ace sessions o g oup class ac i i ies
(Cas illo- A cos e al., 2016; Doubo a e al., 2017; Jeong e al., 2017;
Ma kham e al., 2012; Peskin e al., 2019; Po e e al., 2016; To ole o
e al., 2010). Fo example, dynamics such as g oup ac i i ies, ace-
o- ace ole- playing, and small g oup discussions ha e been shown
o imp o e he beha io al change ou comes o indi iduals (He be
& Loh mann, 2011). Howe e , he e is also e idence showing
posi i e e ec s on beha io s wi h all- digi al in e en ions (Downs
e al., 2004; Noa e al., 2009). The e o e, we can deduce ha one
o he mos impo an poin s o sexual educa ion is he dedica ion
o ime and esou ces o adolescen s and hei pa en s. These digi al
in e en ions can also wo k o imp o e he li e acy o adolescen s in
he media so ha hey can seek accu a e and app op ia e in o ma ion
on hei own (Scull e al., 2018, 2022). Ano he impo an inding o
ou e iew is he e ec s a e no main ained o e ime as much as
we would like (Hu e al., 2023; Jin e al., 2021), because hey begin
o diminish wi h he passage o mon hs. The bene icial e ec o
ein o cemen sessions is no ewo hy (Robe o e al., 2008; Robe o,
Zimme man, Ca lyle, & Abne , 2007; Robe o, Zimme man, Ca lyle,
Abne , Cupp, e al., 2007; Yba a e al., 2013, 2015).
Rega ding he a ge popula ion o he in e en ions, mos wo k
only wi h adolescen s, bu we ound wo in e en ions ha also in-
clude pa en s because hey we e based on he p o ec i e ac o o
amilies in adolescen heal h. Including pa en s in his ype o in-
e en ion means pa en s become mo e awa e o hei child en's
sexual p oblems and imp o e communica ion wi h hem. This im-
p o ed communica ion leads o g ea e knowledge abou STIs and
how o p e en hem, imp o ed sel - e icacy and inc eased in en ion
in heal h beha io s, bu o a lesse ex en (Mu y e al., 2018, 2019;
Va as- Díaz e al., 2019).
Mos in e en ions we e based on heo e ical models o beha -
io change, ecognizing ha he adop ion o his app oach p oduces
be e esul s (Jackson & Wa e s, 2005; Pe e s e al., 2009).
Adhe ence o he in e en ions was e alua ed wi h he e en ion
a e o he di e en s udies, which is gene ally high (abo e 70%); his
sugges s ha he digi al in e en ions we e well accep ed by adoles-
cen s as hey b eak he dynamics o lec u es and classes on sexual
heal h and make he in o ma ion mo e in e es ing o he s uden s.
I also gua an eed he con iden iali y and au onomy hey demanded
(B ayboy e al., 2018).
Rega ding applicabili y, al hough mos o he in e en ions we e
ca ied ou wi h a su icien sample, bu only one s udy de eloped
i s in e en ion in wo di e en coun ies wi h di e en con ex s
o ob ain di e en esul s, s a ing wi h adhe ence o he in e en-
ion by adolescen s, hus demons a ing ha he con ex in luences
he di e en in e en ions o pa icipan cha ac e is ics (Halpe n
e al., 2008).
The s eng h o his sys ema ic e iew is ha i wo ked wi h i e
da abases in addi ion o a p e ious and subsequen e e ence sea ch
o all he a icles o add new possible s udies o he e iew wi hou
language, publica ion da e, o o he es ic ions and wi h a ocus on
RCTs and quasi- expe imen al s udies o inc ease he quali y o he
esul s. Only in e en ions conduc ed wi hin schools we e consid-
e ed o inclusion. The me hodological quali y o he included s ud-
ies anged om high o mode a e. I is possible ha some ele an
s udies may ha e inad e en ly been omi ed, despi e ou ca e ul
selec ion o comp ehensi e keywo ds.
Howe e , he he e ogenei y in e ms o di e ences in in e en-
ions, s udy designs, me hodologies, and a iables used o ou come
measu es p e en s us om p o iding a comp ehensi e syn hesis o
he esul s, because we could no always calcula e he e ec size
o o he measu es ha would acili a e he objec i e compa ison o
one in e en ion wi h ano he . I was di icul o es ablish a speci ic
ime o he sho - and long- e m e ec s, because each in e en ion
had i s ollow- up es s a di e en imes (e.g., 1 mon h, 6 mon hs,
1 yea ), so we ha e desc ibed he esul s by di e en ia ing he
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