DETERMINATION OF MINERAL ELEMENTS IN THE ABOVE GROUND PART OF NONEA PULLA L.

241 Volume 5, Issue 10: Special Issue (EJAR) ISSN: 2181-2020 MPHAPP THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE “MODERN PHARMACEUTICS: ACTUAL PROBLEMS AND PROSPECTS” TASHKENT, OCTOBER 17, 2025 in-academy.uz ETERMINATION OF MINERAL ELEMENTS IN THE ABOVE GROUND PART OF NONEA PULLA L. Bozorova L.N. Khalilova Sh.R. Tashkent Pharmaceutical Institute, Tashkent city, Republic of Uzbekistan e-mail: [email protected] https://doi.org/10.5281/zenodo.17333469 Relevance: Nonea pulla L. is one of the promising medicinal plants, containing tannins, coumarins, organic acids, anthocyanins, vitamin A, ascorbic acid, amino acids, polysaccharides, flavonoids, alkaloids, and microelements, but this plant has not been sufficiently studied. In order for this medicinal plant to be used in scientific medicine, its purity must meet the requirements. It should be noted that heavy metals such as cadmium, lead, and mercury are toxic to living organisms and cause various diseases in the human body. In this regard, the problem of the ecological purity of medicinal plants becomes particularly relevant. The purpose of the study. Determination of mineral elements in the aboveground part of Nonea pulla L. Methods and styles. The above-ground part of Nonea pulla L. was collected in Tashkent in 2025 during flowering. ICP-MS mass spectrometry was used to determine the mass of substances using the inductively coupled plasma method, a method of studying substances based on determining the mass of charge per mass of ions formed when components are ionized. Results. As a result of the research, Nonea pulla L. can be ranked in descending order of the amount of mineral elements in the aboveground part: (Table 1): K> Ca> P> Na> Mg> Fe> Al> Zn> Ba> Sr> B> Mn> Cu> Pb> Ti> Rb> Cr> Ni> Ga> Li> V >Mo > Ce > Sc> Co> La> Zr> Se> U> Bi> Te> Y> As> Sb> Nd> Pr> W> Sn> Th> Ag> Sm> Cs> Gd> Dy> Cd> Eu> Pt> Au> Er> Nb> Yb> Ho> Hf> Be> Lu> Tb=Tm= Ta=Re= TI >In. Table 1 The content of mineral elements in the above-ground part of Nonea pulla L. № Element Amount, mg/kg № Element Amount, mg/kg № Element Amount, mg/kg 1. K 36515 22. V 1,89 43. Se 0,443 2. Ca 10875 23. Sc 0,501 44. Te 0,30 3. Mg 1439 24. Co 0,463 45. Hf 0,016 4. P 1879 25. Ga 2,34 46. Be 0,014 5. Al 769 26. Nb 0,041 47. Pt 0,05 6. Fe 875 27. Cs 0,096 48. Au 0,05 7. Na 1474 28. Sn 0,151 49. La 0,462 8. Sr 78 29. Sb 0,229 50. Zr 0,457 9. B 70,8 30. Pr 0,166 51. Y 0,294 10. Ti 17,9 31. U 0,370 52. As 0,231 11. Mn 45,8 32. Sm 0,111 53. Nd 0,207 12. Ba 129 33. Gd 0,093 54. W 0,16 13. Zn 136 34. Ag 0,127 55. Th 0,148 14. Cu 24,4 35. Dy 0,083 56. Tb 0,01 15. Mo 1,58 36. Cd 0,080 57. Tm 0,01 242 Volume 5, Issue 10: Special Issue (EJAR) ISSN: 2181-2020 MPHAPP THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE “MODERN PHARMACEUTICS: ACTUAL PROBLEMS AND PROSPECTS” TASHKENT, OCTOBER 17, 2025 in-academy.uz 16. Rb 11,7 37. Eu 0,072 58. Ta 0,01 17. Li 2,13 38. Bi 0,341 59. Re 0,01 18. Cr 7,4 39. Er 0,048 60. TI 0,01 19. Ni 2,40 40. Yb 0,040 61. In 0,005 20. Pb 1,4 41. Ho 0,019 21. Ce 1,15 42. Lu 0,01 Summary. For the first time, the amount of mineral elements in the aboveground part of Nonea pulla L. was determined using the ICP-MS (inductively coupled plasma mass spectrometry) method. The concentration level of toxic elements was within the established values, which allowed the recommended medicinal plant to be included in the list of environmentally friendly products.