OBTAINING A HERBAL COMPOSITION WITH HEPATOPROTECTIVE PROPERTIES AND DETERMINING THE QUALITY INDICATORS IN ITS COMPOSITION

332 Volume 5, Issue 10: Special Issue (EJAR) ISSN: 2181-2020 MPHAPP THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE “MODERN PHARMACEUTICS: ACTUAL PROBLEMS AND PROSPECTS” TASHKENT, OCTOBER 17, 2025 in-academy.uz OBTAINING A HERBAL COMPOSITION WITH HEPATOPROTECTIVE PROPERTIES AND DETERMINING THE QUALITY INDICATORS IN ITS COMPOSITION Serikbaeva A.M. M. Auezov South Kazakhstan Research University E-mail: [email protected] Tel: +7 7713279950 Shymkent, Republic of Kazakhstan https://doi.org/10.5281/zenodo.17337102 Relevance: The search for herbal remedies that increase the liver’s resistance to the harmful effects of toxins and stimulate detoxification processes is relevant . Objective: To study the herbal hepatoprotective kit, which consists of seven herbal raw materials (batuten flowers, yarrow herb, tea herb, chamomile flowers, itoshagana herb, tentacle leaves, Shona roots. Research methods. A study of the morphological, anatomical, and quantitative parameters of the hepatoprotective properties was conducted using the generally accepted methodology of the State Pharmacopoeia of the Republic of Kazakhstan. The qualitative composition of biologically active substances in the plant material was determined using phytochemical analysis. Physicochemical methods were used to determine antioxidant activity (spectrophotometry), quantitative analysis of the content of broad-spectrum substances (permanganatometry), and flavonoids (spectrophotometry). Results: A new composition used in the treatment and prevention of liver diseases was developed. The composition of the collection was theoretically and experimentally substantiated. Microscopic and macroscopic analysis, quantitative and qualitative composition, key raw material parameters (moisture, ash, impurities, etc.), and toxicity were determined. We developed our own method for creating a savings ratio based on V. A. Kurkin's method. We recommend selecting two plant materials considered basic and obtaining a quantity twice that of the other materials. Therefore, due to their pronounced choleretic, antioxidant, and hepatoprotective effects, batuten flowers and chaykurai grass received 2 parts, while the remaining auxiliary components received 1 part each. The prepared kit is presented as a "hepatoprotective kit" and consists of: button flowers 2 parts, shoinain roots 1 part, tentacle leaves 1 part, shaker grass 2 parts, yarrow grass 1 part, chamomile flowers 1 part, itoshagan grass 1 part. Table 1. Relative weight of white rats receiving an aqueous infusion from the kit used in the prevention and treatment of liver diseases.