Herbal hair removal solution: Exploring Murraya koenigii for safe and natural depilation powder

 Corresponding author: Sadhana Singh Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0. Herbal hair removal solution: Exploring Murraya koenigii for safe and natural depilation powder Sadhana Singh *, Shashank Tiwari, Amisha Kumari and Gulam Juned Lucknow Model College of Pharmacy, Lucknow, UP, INDIA. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 Publication history: Received on 28 April 2025; revised on 05 June 2025; accepted on 07 June 2025 Article DOI: https://doi.org/10.30574/wjbphs.2025.22.3.0583 Abstract The primary API Murraya koenigii is the subject of this study, which focuses on the creation and assessment of a natural, safe hair removal powder using natural compounds with skin-benefitting properties. Black salt, neem powder, mentha powder, tulsi powder, rose powder, turmeric, rice flour, sandalwood powder, orange peel powder, liquorice powder, multani mitti (fuller's earth), and barium sulfide are among the other natural components used in hair removal powder. These components were selected due to their reputation for enhancing skin health and reducing the visibility of unwanted body hair. The quantities of each ingredient were carefully adjusted during the formulation process to ensure maximum effectiveness while maintaining skin safety. The powder's physical characteristics, such as its color, texture, smell, and the distribution of its particles, were evaluated. Furthermore, the evaluation and feedback from users were utilized to assess the powder's compatibility with the skin and its efficiency in removing hair. The study's results indicate that a body hair removal powder containing multiple beneficial ingredients was successfully created. The appeal to customers seeking gentler alternatives to hair removal treatments that contain chemicals is heightened by the inclusion of natural substances. Further enhancements could be explored in future research and development to optimize the powder's capabilities and increase its market appeal Keywords: Polyherbal; Hair removal; Depilatory; Murraya koenigii; Barium sulfide 1. Introduction The human body contains approximately 100,000 to 150,000 hairs, and each one goes through various stages of growth and shedding throughout its life cycle. Hair is primarily composed of proteins. These proteins are part of the stiff, fibrous keratin class. Long chains of amino acids constitute proteins. Keratin proteins are responsible for forming the cytoskeleton of all cells in the epidermis. The amino acid cysteine constitutes the majority of the keratin proteins found in hair fibers. The sulfur atoms in the cysteine molecules are connected by the bonds of substances called disulfides. Breaking these strong disulfide bonds is quite challenging due to their strength. The chemical bonds formed by disulfide groups in keratins are the primary determinant of the lifespan and resilience of hair fibers, as well as their ability to withstand environmental stressors. The three phases of hair growth are anagen, catagen, and telogen. Hair is generated in the hair follicle, which is a cylindrical indentation located in the outermost layer of the skin. Hair is composed of a slender, flexible structure of dead cells. Many of the amino acids that make up hair contain sulfur and cysteine, which is the most prevalent amino acid found in hair. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 168 Figure 1 Anatomy of Hair Hair growth in unwanted areas of the body is a problem that both men and women must deal with. Unwanted hair is believed to affect a person's ability to appear their best, even if it poses no health risks. Unwanted body and facial hair contributes to one's overall aesthetic appeal. Humans have struggled with unwanted hair for a long time. Approximately 21% of women suffer with excessive facial hair, particularly on the chin and upper lips, and over 80% of women struggle with excessive hair growth . Thus, hirsutism—the male-patterned development of hair on a woman's body—is one of the current conundrums. Numerous methods have been used for a long time to get rid of unwanted hair, but each one has some drawbacks or adverse effects, which are listed below. Figure 2 Hair Growth Cycle Hair Removal Methods and their Consequences: Table 1 Comparison of Hair Removal Methods and Their Consequences Sr. No Hair removing method Consequences 1 Plucking & waxing It’s painful & time-consuming process. Folliculitis may occur 2 Depilatory creams Fast regrowth, redness, irritation & darkening of skin are associated with it 3 Shaving Time consuming & Folliculitis may occur 4 Electrolysis/laser/intense pulse light(IPL) Sometime painful, expensive, risk of hyper pigmentation, rare cases of hypertrichosis and scarring also reported4 5 Antiandrogen /oral contraceptives Long term treatment required, menstrual problems can occur as an adverse effect 6 Substitute cream (Eflornithine) ) Indefinite use require & not actually remove hairs but help to stop regrowth World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 169 2. Material and Method The table below lists several ingredients and how they are used to make hair removal powder. Table 2 Ingredients Used in Herbal Hair Removal Powder and Their Benefits Sr. No. Materials Uses 1 Murraya koenigii Promote hair growth, prevent hair loss 2 Barium Sulphide Used in hair removal 3 Tulsi powder Reduce hair loss 4 Orange powder Add shine and luster to hair 5 Santalum album Anti-dandruff and hair growth 6 Rice flour powder Remove dirt oil, reducing breakage 7 Neem power Clearing dandruff, Treating lice 8 Mentha powder Reduce hair fall 9 Black salt Improve hair health 10 Liquorice powder Promotes shine and softness hair 11 Rose powder To remove hair painlessly & skin smooth 12 Bentonite clay Out impurities and excess oil 13 Turmeric Anti-inflammatory properties 2.1. Plant material 2.1.1. Curry Patta (antioxidants) API • Biological source: - It is obtained from dried leave powder of the Murraya koenigii . Family: - Rutaceae Physical characteristic:- • ColourDark green or blackish green • OdourAromatic • TasteBitter • SizeEach leaflet is 0.79–1.57inch long and 0.39–0.79 inch broad. • Shape-Ovate lanceolate • TextureShiny and smooth Chemical constituents: Murraya koenigii contains a wide variety of organic substances, including sterol, alkaloids, flavonoids, and carbohydrates. UsesCurry leaves are high in antioxidants, vitamins (A, B, C, and E), minerals, and other health benefits, such as the ability to improve digestion, promote healthy hair, lower cholesterol, control diabetes, and have anti-inflammatory and antibacterial qualities that help treat acne, minimize blemishes, and promote a healthy, radiant complexion. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 170 Figure 3 Murraya koenigii Leaves Figure 4 Murraya koenigii leaves powder 2.1.2. Sandalwood Powder- (Soothes and calms skin) Biological source: Sandalwood oil is obtained by distillation of sandalwood, Santalum album Linn. Family: Santalaceae Physical characteristic:- • ColourPale yellow • OdourAromatic or characteristic • TasteUnpleasent • Solubility-Freely soluble in alcohol and slightly soluble in water • TextureSoft and silky feel • Chemical constituents: Two to five percent of sandalwood's volatile oil is made up of 90 to 97 percent sesquiterpene alcohols, or "santalols," of which 95 percent are two isomers. Aldehyde santalol, αand Bsantalol, sesquiterpene alcohol, santene, and santenone. • Uses: Inflammatory skin disorders are lessened with the use of chandan powder. also aids in reducing skin irritation and acne, possesses cooling qualities. Sandalwood's antibacterial and antimicrobial properties may prove beneficial. It helps lessen the irritation, redness, and itching that scabies causes. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 171 Figure 5 Sandal Wood Figure 6 Sandalwood powder 2.1.3. Rice flour (A gantle exfoliant) • Biological source: Rice is the seed of the grass species Oryza sativa (Asian rice). • Family: Poaceae/ Gramineae Physical characteristic • ColourWhite or slightly off-white • OdourVery mild or almost odourless • TasteSlightly sweet or neutral • SizeVary small, fine granules. • Shape-Fine, powdery particles • TextureSoft and smooth • SolubilityInsoluble in cold water but soluble in hot water • Chemical constituents: Rice flour has a moisture content of 8.5% to 13% and is mostly made up of starch (amylose and amylopectin), although it also contains protein, fat, fiber, and ash. • Uses: For millennia, people from many cultures have used rice flour as a natural and affordable way to decrease facial hair.Compounds in rice flour help weaken hair follicles, slow down hair growth over time, and lower sebum levels. A tried-and-true ingredient, rice flour helps to make skin bright and smooth.eliminates pollutants and sun tan from the skin. Have anti-oxidant qualities. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 172 Figure 7 Rice flour Figure 8 Rice flour powder 2.1.4. Orange Peel Powder: (antioxidants or natural exfoliant) • Biological source: Orange peel is the fresh or dried outer part of the pericarp of Citrus aurantium Linn, • Family: Rutaceae Morphology • ColourBright orange to yellow-orange color. • OdourStrong and citrusy aroma • TasteSlightly bitter with a hint of sweetness • SizeFine powder. • ShapeClump together. • TextureSoft and smooth • SolubilityIt is not highly soluble in water but can be infused into liquids and will impart flavor and color. • Chemical constituents: The orange peel contains 23% sugar, 22% cellulose, 25% pectins and 11% hemicellulose. • Uses: Exfoliation, acne therapy, skin whitening, anti-aging effects, oil management, and calming qualities are just a few of the skincare advantages that orange peel powder provides. Packed with vitamin C and antioxidants, it promotes a glowing complexion, lightens dark spots, and improves skin tone when added to homemade face masks or scrubs. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 173 Figure 9 Orange Peel Figure 10 Orange peel powder 2.1.5. Turmeric (Traditional medicines system) • Biological source: Curcumin is the active ingredient of the dietary spice turmeric and is extracted from the rhizomes of Curcuma longa. • Family: Zingiberaceae Morphology: • ColourBright yellow to deep orange. • OdourEarthy, aromatic • TasteBitter, slightly pungent, warm • SizeAs a powder its fine, whole dried rhizomes are about 2-5 cm log • ShapePowder is fine and rhizomes are cylindrical or irregular • TextureSoft and smooth, rhizomes are hard and rough • SolubilitySoluble in water, alcohol and oils • Chemical constituents: The most prominent curcuminoids found in turmeric are curcumin, demethoxycurcumin, and bisdemethoxycurcumin. Turmeric's vivid yellow hue and several biological properties are attributed to these polyphenolic chemicals. • Uses: Turmeric may aid in blood purification and nourishment, which could result in skin that is healthy and radiant. Because of its antibacterial, anti-inflammatory, antiseptic, and antioxidant qualities, it may help treat skin conditions including eczema and acne. Additionally, it might prevent premature aging. Additionally, sunscreens and cosmetics contain turmeric. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 174 Figure 11 Turmeric root Figure 12 Turmeric Powder 2.1.6. Multani Mitti (Exfoliation and cleansing) • Biological source: Its type of clay, not a plant and also known as ‘Bentonite clay’. It is primarily composed of hydrated aluminum silicates with varying amounts of other mineral such as kaolinite and montmorillonite. Morphology: • ColourLight brown, yellowish, pale, off-white • OdourOdourless • TasteEarthy or bland • SizeCommercially available in powdered form and raw clay chunks can vary in size • ShapePowdered is amorphous and irregular in crude form • TextureSoft and smooth, and fine powdered • SolubilityInsoluble in water and organic solvents but it swells and form a paste when mixed with water • Chemical constituents: The main constituents of multani mitti are hydrated aluminum silicates. Its absorbing qualities also come from the presence of calcium bentonite and magnesium chloride. It also includes water, silica, alumina, iron oxide, magnesium oxide, and lime. • Uses: It may have anti-inflammatory, anti-acne, astringent, and skin-brightening properties in addition to exfoliating, cleaning, cooling, and smoothing the skin. World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 175 Figure 13 Multani Mitti Stone Figure 14 Multani Mitti Powder 2.1.7. Barium sulphide (hair removal) One chemical ingredient found in depilatory lotions for hair removal is barium sulfide. It functions by dissolving hair proteins, which facilitates their removal. But for certain people, it can result in allergic reactions and skin irritation. It is important to use goods containing barium sulfide with caution. Figure 15 Barium Sulphide Powder 2.1.8. Tulsi leave (Skin tone improve) • Biological source: Tulsi consists of fresh and dried leaves of Ocimum sanctum Linn. Family: Labiatae. Morphology: • ColourGreen or purplish-green • OdourStrong, aromatic and slightly spicy • TastePungent, slightly bitter • SizeAbout 2-4 cm long • ShapeOval with a pointed tip and slightly toothed edges • TextureSoft or slightly hairy • SolubilityInsoluble in water but tulsi extract or oil is soluble in alcohol or oil based solvent • Chemical constituents: Bright, yellow, and pleasant volatile oil (0.1 to 0.9%) is found in tulsi leaves. It has about 70% eugenol, 3% carvacrol, and 20% eugenol-methyl-ether. Alkaloids, glycosides, saponin, tannins, a World Journal of Biology Pharmacy and Health Sciences, 2025, 22(03), 167-183 182 4. Conclusion Hair removal powder contains various ingredients barium sulphide, Murraya koenigii, mentha powder, tulsi powder, etc. With different pharmacological properties to potentially provide multiple benefits for the skin. A depilatory agent barium sulfide, which means it can dissolve hair at the surface of the skin, facilitating hair removal however, the efficacy and safety of such product depend on various factors, including individual skin type, sensitivity, and potential allergies, irritation to any of the ingredients. It is crucial to conduct a patch test before using the product extensively and to adhere to the recommended usage instructions to minimize the risk of adverse reactions caused by the herbal substances and plants commonly encountered in daily life. Certain plants possess natural compounds known as phytoconstituents, which may have medicinal and hair removal properties. All the formulations were assessed for their physical and chemical properties as well as their therapeutic effects. Based on the findings, it can be concluded that the hair removal powder is made by combining chemical ingredients and herbs. Compliance with ethical standards Disclosure of conflict of interest No conflict of interest. References [1] Tiwari, S., & Talreja, S. (2020). A Pharmaceutical Importance of Murraya koenigii-A Complete Study. Indian Journal of Public Health Research & Development, 11(11), 276284. [2] Tiwari, Dr & Singh, Sadhana. (2024). A comprehensive review of acne's facial impact and the therapeutic potential of Indian herbal medicine. World Journal of Advanced Research and Reviews. 23. 1148-1155. 10.30574/wjarr.2024.23.3.2738. 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