Clonal cell states link gastroesophageal junction tissues with metaplasia and cancer

R = 0.29, p < 2.2e−16R = 0.47, p < 2.2e−16R = 0.39, p < 2.2e−16R = 0.36, p < 2.2e−16R = 0.012, p = 0.7R = −0.049, p = 0.11 0.00 0.25 0.50 0.75 0 1 2 3 4 Ki67 Expression S Phase Score Cell Type a a a a a a BE SQ GC IM FB VC NS Ki67 vs S Phase Score R = 0.74, p < 2.2e−16R = 0.85, p < 2.2e−16R = 0.75, p < 2.2e−16R = 0.61, p < 2.2e−16R = 0.058, p = 0.06R = 0.26, p < 2.2e−16 0.0 0.5 1.0 0 1 2 3 4 Ki67 Expression G2M Phase Score Cell Type a a a a a a BE SQ GC IM FB VC NS Ki67 vs G2M Phase Score R = 0.63, p < 2.2e−16R = 0.79, p < 2.2e−16R = 0.61, p < 2.2e−16R = 0.4, p < 2.2e−16R = 0.016, p = 0.6R = 0.071, p = 0.021 0.0 0.5 1.0 1.5 0 1 2 3 4 Ki67 Expression Custom Cycling Score Cell Type a a a a a a BE SQ GC IM FB VC NS Ki67 vs Custom Cycling Score Comparison of Cell Cycle Metrics with Ki67 Expression