NGFF slides - Ambassador Toolkit

Historical Context All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 Image Data Management isn’t always FAIR 5 "Clara shares" by Henning Falk, ©2022 NumFOCUS, is used under a CC BY 4.0 license. https://github.com/zarr-developers/zarr-illustrations-falk-2022#clara-shares Image: Simon Li https://twitter.com/penguinoops/status/643812318699225088 All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 A brief history of making images go 6 2000 2024 JSON RFC (2006) “FAIR” Wilkinson (2016) 2005 2016 2018 "Bea computes" by Henning Falk, ©2022 NumFOCUS, is used under a CC BY 4.0 license. https://github.com/zarr-developers/zarrillustrations-falk-2022#bea-computes All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 10 2000 Goldberg, et al. (2005) The Open Microscopy Environment (OME) Data Model and XML File: Open Tools for Informatics and Quantitative Analysis in Biological Imaging. Genome Biol. 6:R47. DOI:!10.1186/gb-2005-6-5-r47!" https://bit.ly/citing-ome XML All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 21 Collaborate on data publication Annotate Rapidly edit figures https://lincs-omero.hms.harvard.edu http://ssbd.qbic.riken.jp/ https://www.mousephenotype.org 2005 All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 28 Integrated studies Analysis results Biomolecular annotations Experimental metadata Thumbnails (of 5D Images) Geographic HCS Histopathology 3D-Sim Super-resolution Gene Product Targeting HCS Genetic HCS Chemical HCS Cross-data browsing Download (local analysis) Cloud analysis https://idr.openmicroscopy.org 2016 Williams et al. (2017) The Image Data Resource: A Bioimage Data Integration and Publication Platform. Nature Methods 14(8), 775-781. Published 19 June 2017 DOI:!10.1038/nmeth.4326! https://bit.ly/citing-ome All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 30 ~ 78,000 Unique IPs ~34 M hits 2016 All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 Analysis clients & libraries Remote Local On-the-fly translation Proprietary File Formats (PFF) Imaging repositories Upload 38 2018 Download All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 Analysis clients & libraries Remote Local On-the-fly translation Proprietary File Formats (PFF) Imaging repositories Upload 39 2018 Download ??? IUPAB&·&Josh&Moore&·&Scalable'Strategies'(2024-06-28)10.5281/zenodo.12511192 11 -TIFF (Pyramidal) •Benefit: Pre-calculated multi-resolution improves viewing. •Challenge: Still limited annotation capabilities. • Strategy: Provide a data management platform. https://www.openmicroscopy.org/2018/11/29/ometiffpyramid.html1 Common exchange format (2017-present) Besson1(2019)1Bringing1Open1Data1to1Whole1Slide1Imaging.1Digital1Pathology1ECDP12019.1 Lecture1Notes1in1Computer1Science,1vol111435.1DOI:110.1007/978-3-030-23937-4_11 https://bit.ly/citing-ome IUPAB&·&Josh&Moore&·&Scalable'Strategies'(2024-06-28)10.5281/zenodo.12511192 14 •Benefit: Full power of a database. •Challenge: Custom API, bottleneck. • Strategy: Cloud protocol (Zarr). Data Management Platform (2005-present) Allan(et(al.((2012).(OMERO:'flexible,'model-driven'data'management'for'experimental'biology.' Nature(Methods(9,(245–253.(Published:(28(February(2012(DOI:(10.1038/nmeth.1896(( hEps://bit.ly/ciOng-ome Josh Moore · EBI Webinar (2025-05-28)10.5281/zenodo.15479606 One file can contain one image 14 https://ome.github.io/presentations/2013/fs-workshop-paris/#/7/3 Josh Moore · EBI Webinar (2025-05-28)10.5281/zenodo.15479606 One file can contain multiple images 15 https://ome.github.io/presentations/2013/fs-workshop-paris/#/7/3 Josh Moore · EBI Webinar (2025-05-28)10.5281/zenodo.15479606 Many files can make many images 16 https://ome.github.io/presentations/2013/fs-workshop-paris/#/7/3 Josh Moore · EBI Webinar (2025-05-28)10.5281/zenodo.15479606 Bioimaging & Heterogeneity High-content Screen Single-cell tissue Complex Acquisitions 5D Images 3D, multi-color, movies, or any combination https://ome-model.readthedocs.io/ Diversity in imaging applications/modalities 20 January 2025 Raw data size 411 TB Image files 38 M 5D Images 14 M 2D Planes 118 M Organisms 84 Genes 89 K Antibodies 12 K Compounds 40 K IDR Organism NCBI Taxonomy https://www.ncbi.nlm.nih.gov/taxonomy Study Type Screen Type (HCS) Screen Technology Type (HCS) Library Type (HCS) Protocol Experimental Factor Ontology (EFO) https://www.ebi.ac.uk/efo/ Imaging Method Biological Imaging Methods Ontology (FBbi) https://www.ebi.ac.uk/ols/ontologies/fbbi Phenotype Cellular Microscopy Phenotype Ontology (CMPO) https://www.ebi.ac.uk/cmpo/ Gene Ensembl https://www.ensembl.org/ NCBI Gene https://www.ncbi.nlm.nih.gov/gene/ Protein UniProt https://www.uniprot.org/ Clinical/Pathology SNOMED CT https://bioportal.bioontology.org/ontologies/ SNOMEDCT Compound PubChem https://pubchem.ncbi.nlm.nih.gov/ Imaging in the wider EBI data context Slide credit: Matthew Hartley OME2025 Slide credit: Matthew Hartley BIA User Forum 2025 Bioformats Josh Moore · EBI Webinar (2025-05-28)10.5281/zenodo.15479606 34 34 bfconvert \ meoh.nd2 \ meoh.ome.tiff https://downloads.openmicroscopy.org/images/ND2/aryeh/ Conversion NGFF fundamentals CC-BY Josh Moore | Presented to Zeiss, 2.July 2025 3 Why OME-ZARR as a format? What problem does it solve? What is the future of OME-TIFF? Where do you see the benefits for a vendor when incorporating such a format? Is the NGFF Converter not enough? CC-BY Josh Moore | Presented to Zeiss, 2.July 2025 4 Where do you see the benefits for a vendor when incorporating such a format? Is the NGFF Converter not enough? Accessing images without download Images by @DrHenningFalk,! ©2022 @NumFOCUS is used under a CC-BY 4.0 license. Why OME-ZARR as a format? What problem does it solve? What is the future of OME-TIFF? CC-BY Josh Moore | Presented to Zeiss, 2.July 2025 5 Where do you see the benefits for a vendor when incorporating such a format? Is the NGFF Converter not enough? Standardizing the access protocol Neuroglancer Jeremy Maitin-Shepard, Google MoBIE Plugin Christian Tischer, EMBL Heidelberg webKnossos Norman Rzepka, scalableminds Images by @DrHenningFalk,! ©2022 @NumFOCUS is used under a CC-BY 4.0 license. Why OME-ZARR as a format? What problem does it solve? What is the future of OME-TIFF? CC-BY Josh Moore | Presented to Zeiss, 2.July 2025 8 Where do you see the benefits for a vendor when incorporating such a format? Is the NGFF Converter not enough? Download / “Cloud” Repositories & Archives Standard access protocol Developer interest Why OME-ZARR as a format? What problem does it solve? What is the future of OME-TIFF? CC-BY Josh Moore | Presented to Zeiss, 2.July 2025 9 Where do you see the benefits for a vendor when incorporating such a format? Is the NGFF Converter not enough? No deprecation plans. Community (developer) support is limited. Adobe owns TIFF license. Performance is limited. Meta/data structures are limited. Why OME-ZARR as a format? What problem does it solve? What is the future of OME-TIFF? CC-BY Josh Moore | Presented to Zeiss, 2.July 2025 17 Value Cost No standard Having a standard Implementation spectrum: … “Full adoption” Export Import Translation • Ownership • Velocity • Quality* • Development • User support • Bio-Formats dependency* • maintenance • User experience* • Stability* • Interoperability • Mandatory? • AI-readiness • Engagement with process • Risk of stalling • Depth & breadth of implementations* * User impact https://forum.image.sc/t/streaming-czi-files-not-openingproperly-using-bio-formats-in-qupath-and-imagej/112218 BioVisionCenter · Josh Moore · NGFF-RFC (2024-11-18) 10.5281/zenodo. 13991322 4 Becoming OME-Zarr 4 example/ ├── s0 # Full-sized ├── s1 └── s2 # Smallest example/ ├── 0 # Full-sized ├── 1 └── 2 # Smallest example/ ├── 0 # Smallest ├── 1 └── 2 # Full-sized { “multiscales”: [ { “datasets” : [ {"path": “0"}, {"path": “1"}, {"path": "2"} https://github.com/zarr-developers/zarr-specs/issues/50 https://ngff.openmicroscopy.org/0.4/#multiscale-md ... I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 Photo by Scott Webb on Unsplash 23 -Zarr Next-generation file format (2018-present) I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 Quickstart 13 https://www.glencoesoftware.com/products/ngff-converter/ I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 Quickstart 14 I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 Quickstart 15 BINA CC · Josh Moore · Scalable Strategies (2024-09-24)10.5281/zenodo.13747937 29 29 example/ ├── 0 # Full-sized ├── 1 ├── 2 ├── 3 └── 4 # Smallest example/ ├── 0 # Smallest ├── 1 ├── 2 ├── 3 └── 4 # Full-sized example/ ├── s0 # Full-sized ├── s1 ├── s2 ├── s3 └── s4 # Smallest { “multiscales”: [ { “datasets” : [ {"path": "0"}, {"path": "1"}, {"path": "2"}, {"path": "3"}, {"path": "4"} ] https://github.com/zarr-developers/zarr-specs/issues/50 NGFF Example https://ngff.openmicroscopy.org/0.4/#multiscale-md IUPAB&·&Josh&Moore&·&Scalable'Strategies'(2024-06-28)10.5281/zenodo.12511192 15 Chunkable&file&format Monolithic&file&format SPLIT CONCATENATE NETWORK NETWORK Access&via&network External&data&storage Local&computer -Zarr Next-generation file format (2018-present) Moore(et(al.((2021).(OME-NGFF:'a'next-generaAon'file'format'for'expanding'bioimaging'data-access'strategies.' Nature(methods((2021).(Published:(29(November(2021(DOI:(10.1038/s41592-021-01326-w(( hEps://bit.ly/ciOng-ome https://zarr.dev/adopters1:1 viewed&in (“Cloud-optimized”) IUPAB&·&Josh&Moore&·&Scalable'Strategies'(2024-06-28)10.5281/zenodo.12511192 16 ITKWidgets Neuroglancer AGAVE -Zarr Next-generation file format (2018-present) Moore(et(al.((2021).(OME-NGFF:'a'next-generaAon'file'format'for'expanding'bioimaging'data-access'strategies.' Nature(methods((2021).(Published:(29(November(2021(DOI:(10.1038/s41592-021-01326-w(( hEps://bit.ly/ciOng-ome IUPAB&·&Josh&Moore&·&Scalable'Strategies'(2024-06-28)10.5281/zenodo.12511192 18 -Zarr Next-generation file format (2018-present) Moore(et(al.((2021).(OME-NGFF:'a'next-generaAon'file'format'for'expanding'bioimaging'data-access'strategies.' Nature(methods((2021).(Published:(29(November(2021(DOI:(10.1038/s41592-021-01326-w(( hEps://bit.ly/ciOng-ome https://idr.github.io/ome-ngff-samples1 IUPAB&·&Josh&Moore&·&Scalable'Strategies'(2024-06-28)10.5281/zenodo.12511192 20 -Zarr Next-generation file format (2018-present) https://www.ebi.ac.uk/bioimage-archive/galleries/galleries.html11 Credit:1Matthew1Hartley1(OME2024) Josh Moore · EBI Webinar (2025-05-28)10.5281/zenodo.15479606 51 02.04.2025 Credit: Christian Schmidt bit.ly/n4bi-100gb-mobile https://ome.github.io/ome2024-ngff-challenge/ Possibilities OME-TIFF Cloud native Chunked protocol Built-in compression https://zarr.dev/adopters ESA* NGFF spec/RFCs BioVisionCenter · Josh Moore · NGFF-RFC (2024-11-18) 10.5281/zenodo. 13991322 ngff.openmicroscopy.org 3 BioVisionCenter · Josh Moore · NGFF-RFC (2024-11-18) 10.5281/zenodo. 13991322 RFC: How we make (record) decisions 7 https://www.ietf.org/download/rfc-index.txt https://www.ietf.org/about/groups/rfc-editor/ BioVisionCenter · Josh Moore · NGFF-RFC (2024-11-18) 10.5281/zenodo. 13991322 RFC: How we make (record) decisions 10 https://ngff.openmicroscopy.org/rfc/1/index.html#stakeholders Draft phase Issue, Thread, etc. Copy the template Clarify Merge RFC phase Gather endorsements Pass review Spec phase Update the spec Implement! BioVisionCenter · Josh Moore · NGFF-RFC (2024-11-18) 10.5281/zenodo. 13991322 12 I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 36 Bad news: Doesn’t solve everything. Agreeing can be hard (and slow), too. Good news: Lot of excitement. Let’s us do harder things faster. I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 37 2018 Kick-off 2020 0.1 (Multiscales, Labels, HCS) 2021 0.2-0.3 (Performance, Axes) 2022 0.4 (Axes type, units, transforms) 2023 Tables & coordinate transforms 2024 RFCs (1-5) ngff.openmicroscopy.org/rfc Live release soon! / I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 38 2018 Kick-off 2020 0.1 (Multiscales, Labels, HCS) 2021 0.2-0.3 (Performance, Axes) 2022 0.4 (Axes type, units, transforms) 2023 Tables & coordinate transforms 2024 RFCs (1-5) 2025 Transforms ‣OME-TIFF equiv. ‣Acquisition ‣Extensibility ‣“As simple as possible but not simpler” 1.0 ASAP .………………………………………… 0.5: Zarr v3 (RFC-2) Sharding: ZEP1 Extensibility: ZEP9 & ZEP10 (in progress) Adoption growing vs 0.4 https://zarr.dev/zeps Tagged 0.6.dev1 in April (OME2025) Targeting 0.6.dev2 later this summer Conversions & samples needed 0.6: Transforms (RFC-5) Credit: John Bogovic OME2025 Meeting, Session 4 “Doing it together” April 30th, Woods Hole YouTube playlist All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 7 I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 26 ome2024-ngff-challenge I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 27 ome2024-ngff-challenge •https://forum.image.sc/t/ome2024-ngff-challenge/97363 ‣1PB ‣“bring your own bucket” ‣proposed next version ‣drive development I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 !Hocus Pocus 31 $ pip install ome2024-ngff-challenge $ ome2024-ngff-challenge resave input.zarr output.zarr I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 32 samples1.csv samples2.csv samples3.csv Svelte.js viewer https://ome.github.io/ome2024-ngff-challenge/ Will Moore (University of Dundee) I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 34 ome2024-ngff-challenge ‣4 months ‣~9 conf. calls ‣several PRs ‣few Ks ($£¥€) ‣50% of goal “most exciting thing about this challenge was bigpicture vision of federated image repositories that speak common language” I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 49 Nature#622, 206-208 (2023) https://doi.org/10.1038/d41586-023-03064-9 "How open-source software could finally get the world’s microscopes speaking the same language" https://news.ycombinator.com/item?id=37737318 I2K · Josh Moore · Scalable Strategies (2024-10-25)10.5281/zenodo. 13991322 Metadata Matters 2010 53 https://doi.org/10.1083/jcb.201004104 (Most cited OME paper) Recommendations for OME Compliant image metadata.!The Image and Instrument Elements from the OME Data Model, with attributes and hierarchies shown in diagrammatic form. The Image Element contains core metadata that can be used for display and processing of the associated binary image data. Currently, an OME Compliant image completes all of the metadata in the Image Element. By the end of 2010, we aim to include the Instrument Element in the OME Compliant specification. The Bio-Formats library provides support for writing OME-XML either as a stand-alone file or within the header of an OME-TIFF file. The full XML Schema version of the OME Data Model is available at!http://ome-xml.org/browser/Schemas/OME/2010-04/ ome.xsd. Updates to the OME Data Model are announced on the project’s roadmap site (http://ome-xml.org/roadmap). BINA CC · Josh Moore · Scalable Strategies (2024-09-24)10.5281/zenodo.13747937 10 Strategy: Maximize our effort on shared cyberinfrastructure. Challenge: Most of the world’s bioimaging data lacks a clear path to being shared. BINA CC · Josh Moore · Scalable Strategies (2024-09-24)10.5281/zenodo.13747937 Maintaining a model 12 2008 Last!major!modeling! effort!for!highcontent-screening 2010 Added!flexible!structuredannotations!for!user-extensions 2013 Add!key-value!(K/V)!pair!annotation 2016 Use!k/v!for!ontology!links IUPAB&·&Josh&Moore&·&Scalable'Strategies'(2024-06-28)10.5281/zenodo.12511192 26 26 & Vendors Critical relationship from the beginning IUPAB&·&Josh&Moore&·&Scalable'Strategies'(2024-06-28)10.5281/zenodo.12511192 27 27 & Vendors Critical relationship from the beginning Bring experts together …but drive convergence! https://founding-gide.eurobioimaging.eu/ https://nfdi4bioimage.de/about-us/members/co-applicants/ Credit: Stefanie Weidtkamp-Peters OME2025 // cc-by What comes next? 14 Peak of inflated expectations Time Plateau of productivity Trough of disillusionment Chasm Slope of enlightenment Innovators & Enthusiasts Laggards Vigorous resisters Practicals Cautious (early & late majority) Hype cycleAdoption Curve Visibility Community Meeting 2024 04.03.2024 2 3 Technology Development / FAIR-IO in consistent containers ★★★★ Susanne Kunis Stefanie Weidtkamp-Peters Elisa May 2023-2028 Satellite tools All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 46 Interactive visualization and annotation Very large images, standard cloud-native formats Single cell and spatial omics data analysis AnnData SpatialData 2018Today Slide courtesy: Luca Marconato (EMBL) All-Hands Meeting · Josh Moore · Welcome to BioImage Town 16/10/2023 •Issues •Java •Mixed formats 47 Slide courtesy: Luca Marconato (EMBL) Today Community Meeting 2024 04.03.2024 1 9 Technology Development / SpatialData 2023-2025 Single Cell Luca Marconato Giovanni Palla Isaac Virshup Kevin A. Yamauchi that are machine readable ★★★ Resources/training Josh Moore · EBI Webinar (2025-05-28)10.5281/zenodo.15479606 17 Training resources https://neubias.github.io/training-resources/image_file_formats/ http://www.neubias.org/ https://www.globias.org/ Josh Moore · EBI Webinar (2025-05-28)10.5281/zenodo.15479606 18 https://datacarpentry.github.io/image-processing/02-image-basics.html#tiff https://software-carpentry.org/lessons/ https://carpentries.org/ Josh Moore · EBI Webinar (2025-05-28)10.5281/zenodo.15479606 46 More help with OME-Zarr and other big data formats https://neubias.github.io/training-resources/ome_zarr/index.html https://neubias.github.io/training-resources/big_image_file_formats/index.html CMCB Dresden · Josh Moore · Scalable Strategies (2025-01-16)10.5281/zenodo. 14650434 https://image.sc 41 Rueden CT, Ackerman J, Arena ET, Eglinger J, Cimini BA, Goodman A, et al. (2019) Scientific Community Image Forum: A discussion forum for scientific image software. PLoS Biol 17(6): e3000340. https://doi.org/10.1371/journal.pbio.3000340 Acknowledgments? Acknowledgments More welcome! BE VIB Benjamin Pavie // CH Bern Ana Stojiljkovic BioVisionCenter Joel Lüthi, Lorenzo Cerrone, Virginie Uhlmann EPFL Rémy Dornier ETH Kevin Yamauchi, Leonardo Schwarz FMI Franziska Moos, Gustavo de Medeiros, Jan Eglinger, Prisca Liberali Zürich Fabio Steffen, Flurin Sturzenegger, Grégory Paul, Reto Gerber, Ruth Hornbachner // CZ MUNI Vladimír Ulman // DE EMBL Luca Marconato, Oane Gros, Oliver Stegle, Wouter-Michiel Vierdag, Christian Tischer Euro BioImaging Bugra Özdemir German BioImaging Josh Moore, Johannes Soltwedel, Tom Boissonnet Göttingen Constantin Pape Helmholtz München Fabian J. Theis, Giovanni Palla, Isaac Virshup TU Dresden Stefan Hahmann // FR France BioImaging Guillaume GAY Pasteur Daniel Krentzel, Marvin Albert // JP RIKEN Hiroya Itoga, Koji Kyoda, Shuichi Onami // SE Lund University Nils Norlin SciLifeLab Jonas Windhager, Wei Ouyang, Xavier Casas Moreno // UK Crick Joost de Folter, Kenneth Ho, Martin Jones Dundee David Gault, Dominik Lindner, Frances Wong, Jason R. Swedlow, Jean-Marie Burel, Khaled Mohamed, William Moore EBI Aybüke Küpcü Yoldaş, Aybuke Kupcu Yoldas, Francois Sherwood, Kolawole Babalola, Liviu Anita, Matthew Hartley Sanger Omer Bayraktar, Daniela Basurto-Lozada, Dave Horsfall, Muzlifah Haniffa, Tong Li UCL David Stansby // US Allen Daniel Toloudis, Eva M. Brown, Gabor Kovacs, Sean Meharry Broad Beth A. Cimini, Erin Weisbart CZI BioHub Jordão Bragantini, Loic A. Royer, Ahmet Can Solak, Lerlin Lange Dartmouth Yaroslav O. Halchenko HMS Ilan Gold, Mark S. Keller, Nils Gehlenborg, Trevor Manz ITK Matthew McCormick JAX Erick Ratamero, Kiya Govek, Peter Sobolewski Janelia John Bogovic, Konrad Rokicki, Mark Kittisopikul, Stephan Saalfeld, Tobias Pietzsch MIT Satrajit S. Ghosh NIH Hythem Sidky, Nathan Hotaling, Nicholas Schaub, Sameeul Samee Pittsburgh Alan M. Watson UMN Rachael Huxford // Company Glencoe Chris Allan, Erin E. Diel, Melissa Linkert, Sébastien Besson Google Jeremy Maitin-Shepard Roche Dominique Roux, Maximilian Schulz Yikes Eric Perlman scalableminds Albane le Tournoulx de la Villegeorges, Hannes Spitz, Norman Rzepka, Jonathan Striebel Zeiss Sebastian Rhode, Stephan Wagner-Conrad & Many more Christoph Engwer, Davis Bennett, Dmytro Horyslavets, Filip Mroz, Igor Zubarev, Szymon Stoma, Vera Galinova along with 90+ other members of the image.sc group: adamkglaser, aeisenbarth, amathur, Anatole_Chessel, andriy, AnthonyA, arturo.pimentel, avweigel, bene.schmid, berl, berombau, biehli, Bill_Katz, brainio, brossetti, bruno, camlloyd, carandraug, Caterina, cgohlke, Christopher_Steele, ctr26, darshats, DragaDoncila, dsudar, ehrenfeu, EliS, fercer, folterj, frauzufall, GenevieveBuckley, glyg, Gonzalo_Merino, g-sands, Gucki, guiwitz, haesleinhuepf, hanslovsky, heeler, ilan-gold, imagejan, jandilla, jbms, jfkotw, jkh1, jlacoste, jni, JorgeGtz, jqshenker, jstitlow, juliomateos, kabilar, k-dominik, ken.ho, kephale, Kevin_Kozlowski, Kimberly_Meechan, lassoan, LDeakin, Lee_Kamentsky, leoburgy, lguerard, lmurphy, manics, maree, mellertd, memphizz, MinaG, neissner, NicoKiaru, olatarkowska, Oumou_DHMINE, paulkorir, petebankhead, petermajer, Research_Associate, rohola, Sarah_Aufmkolk, schienstockd, schorb, sebherbert, sofroniewn, Steen, Stephen_Taylor, stick, sukunis, talley, tibuch, UlrikeBoehm, uqathom9, VolkerH, Wojtek Goscinski