Beyond Symptom Relief: A Review of Low-FODMAP Diet Implementation in Irritable Bowel Syndrome

Beyond Symptom Relief: A Review of Low-FODMAP Diet Implementation in Irritable Bowel Syndrome Loso Judijanto  IPOSS Jakarta, Indonesia Abstract As a frequently diagnosed disorder of the gastrointestinal tract, Irritable Bowel Syndrome (IBS) has a profound negative impact on patients' quality of life. The Low-FODMAP regimen is increasingly acknowledged as a targeted dietary method for alleviating related symptoms. However, the broader implications of its implementation beyond symptom management require comprehensive evaluation. The objective of this paper is to investigate various perspectives surrounding the use of the Low-FODMAP diet in managing IBS by reviewing existing academic literature. This qualitative analysis is based on peer-reviewed sources published within the 2015–2025 timeframe. Data were collected from four major academic databases through systematic screening based on predefined inclusion criteria. Selected studies included randomised controlled trials, narrative reviews, and clinical guidelines relevant to Low-FODMAP diet implementation. Data analysis employed thematic synthesis to identify key patterns and gaps within the literature. The review synthesised findings from 80 articles, revealing consistent evidence of symptom reduction in the short term, particularly for abdominal bloating and overall IBS severity. Nonetheless, challenges in long-term adherence, nutritional adequacy, and psychosocial impacts were prominent. Limited practitioner training and healthcare system barriers further complicated effective diet implementation. The importance of dietitian support and multidisciplinary care emerged as critical for sustainable patient outcomes. While adherence to the Low-FODMAP dietary approach significantly improves symptom control in IBS patients, its broader implementation demands integrated approaches addressing nutritional, psychological, and systemic factors. Future research should emphasise longitudinal studies, culturally tailored interventions, and strategies to enhance adherence. Introduction IBS is a widely occurring disorder of gastrointestinal function, typically involving ongoing abdominal discomfort, disrupted bowel patterns, and a pronounced effect on daily living and well-being, with global prevalence estimates ranging from 10% to 20% of the adult population [54]. Despite its non-lethal nature, IBS imposes a profound burden on healthcare systems, workplaces, and patients' psychosocial wellbeing [6]. Traditional pharmacological approaches, including antispasmodics, laxatives, and antidepressants, often yield suboptimal or inconsistent symptom relief, thereby shifting attention toward complementary non-pharmacological interventions [20]. Among these, dietary modifications have emerged as a cornerstone of IBS management [22]. The past ten years have seen growing interest in the Low-FODMAP diet within both medical and academic fields, mainly due to its focused method of reducing specific fermentable carbs such as oligosaccharides and polyols that are inefficiently absorbed in the small intestine and quickly metabolised by gut bacteria [31]. The accumulation of gas, water retention, and intestinal bloating that result from FODMAP fermentation have been strongly correlated with the physiological processes responsible for IBS symptoms [49]. Clinical trials and pooled data from meta-analyses have validated the Low-FODMAP diet as a successful intervention for relieving key symptoms of IBS, including abdominal pain, bloating, and irregular defecation patterns [13,28]. More Information How to cite this article: Judijanto L. Beyond Symptom Relief: A Review of Low-FODMAP Diet Implementation in Irritable Bowel Syndrome. Eur J Med Health Res, 2025;3(6):154-64. DOI: 10.59324/ejmhr.2025.3(6).22 Keywords: Low-FODMAP diet, Irritable Bowel Syndrome, qualitative literature review, diet adherence, psychosocial impact. This work is licensed under a Creative Commons Attribution 4.0 International License. The license permits unrestricted use, distribution, and reproduction in any medium, on the condition that users give exact credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if they made any changes. EUR J MED HEALTH RES Volume 3 | Number 6 | 2025 155 While symptom relief remains the primary endpoint in most dietary intervention studies, there is growing recognition that effective IBS management must transcend symptom suppression and address longterm dietary sustainability, patient adherence, nutritional adequacy, and psychosocial outcomes [66]. The structured phases of the Low-FODMAP diet elimination, reintroduction, and personalisation introduce intricate clinical demands that go beyond simple biological or metabolic processes [76]. This complexity becomes especially apparent in real-world dietary counselling, where patients must navigate social eating contexts, cultural food preferences, limited access to specialised dietitians, and often incomplete food labelling [34]. Moreover, growing research highlights that a patient's commitment to the Low-FODMAP diet is determined both by the degree of digestive discomfort experienced and their understanding of health-related information, socioeconomic factors, psychological readiness, and trust in healthcare providers [37]. Such multidimensional influences underscore the necessity of a holistic understanding of how patients integrate dietary advice into their lived experiences, a lens that purely quantitative research may fail to capture [77] fully. As such, the qualitative perspective becomes indispensable in synthesising the nuanced processes through which individuals implement dietary strategies in chronic illness self-management. Despite increasing scholarly interest, existing literature reviews on the Low-FODMAP diet remain predominantly quantitative in nature, often focusing on measurable symptom outcomes rather than on the broader context of dietary adherence, behavioural transformation, or patient-centred perspectives [27]. Systematic and scoping reviews have tended to emphasise statistical trends, clinical endpoints, and evidence hierarchies, which, while valuable, may inadvertently marginalise insights into the lived realities and experiential narratives surrounding diet implementation. This epistemological gap highlights the need for a more interpretive synthesis of literature that privileges meaning, context, and thematic patterns over rigid methodological uniformity [68]. Moreover, while multiple studies have documented the short-term benefits of the Low-FODMAP approach, the literature remains fragmented in evaluating the longterm feasibility, emotional burdens, and sociocultural implications of this dietary regimen [5]. For instance, the reintroduction and personalisation phases are often underreported, leaving a vacuum in clinical guidance and patient support tools. Additionally, there is a paucity of integrative reviews that collate findings from nutrition science, behavioural psychology, and medical sociology to provide a cohesive understanding of the diet’s real-world application [52]. Given these limitations, this study employs a Qualitative Literature Review (QLR) methodology to synthesise interdisciplinary research on the use of the Low-FODMAP dietary approach in IBS care beyond its role in symptom management. Unlike systematic reviews that emphasise exhaustive retrieval and methodological homogeneity, the QLR approach is inherently interpretive, aiming to extract deeper meaning and context from selected bodies of literature across diverse study designs and epistemologies [48]. This method is particularly appropriate for exploring complex health interventions where human behaviour, context, and perception play critical roles in shaping outcomes [72]. The focus of this review is therefore not to reconfirm the symptomatic efficacy of the Low-FODMAP diet already well documented in meta-analyses but to interrogate how patients and practitioners operationalise this intervention in real-world settings. This includes identifying common barriers and facilitators to adherence, evaluating the role of dietitians and multidisciplinary teams, and synthesising perspectives on dietary sustainability, accessibility, and patient empowerment [12]. By centring on implementation rather than efficacy, this review seeks to expand the evaluative lens of IBS dietary management and contribute to more patient-centred and context-sensitive clinical practice. The purpose of this qualitative review is to analyse and synthesise existing research about how the LowFODMAP diet is implemented for IBS patients, focusing particularly on the behavioural, social, and systemic factors that affect adherence and sustainability in healthcare and everyday environments. Literature Review Conceptualising IBS and the Role of Diet Irritable Bowel Syndrome is a complex digestive disorder involving ongoing abdominal discomfort, changes in bowel behaviour, and commonly associated mental health issues such as anxiety and depression [32]. While IBS does not threaten life, it dramatically affects the well-being of patients and remains a significant clinical challenge because of its diverse underlying factors [61]. Dietary modification is recognised as a key adjustable factor among management strategies due to its direct effects on both gut symptoms and microbial processes [15]. Awareness that particular fermentable carbohydrates known as FODMAPs contribute to the worsening of IBS symptoms has driven the formulation of the LowFODMAP diet, which restricts these components to minimise fermentation and gas production in the colon [10]. This dietary approach, while mechanistically supported by gastrointestinal physiology, also implicates broader domains of patient education, adherence, and long-term sustainability [53]. EUR J MED HEALTH RES Volume 3 | Number 6 | 2025 156 Efficacy of the Low-FODMAP Diet: Evidence and Limitations Clinical trials and real-world studies alike have consistently found the Low-FODMAP diet effective in diminishing symptoms such as bloating, flatulence, diarrhoea, and abdominal pain [60]. Meta-analyses and randomised controlled trials indicate that approximately 70% of IBS patients report symptomatic improvement following a low-FODMAP regimen [53]. However, these findings are often confined to shortterm symptom relief and rarely address how patients interact with and maintain the diet over time. Furthermore, many of these studies prioritise symptom metrics and neglect the psychosocial and behavioural contexts that influence dietary success or failure. Consequently, while the clinical validation of the LowFODMAP diet is well established, its real-world implementation is underexplored and poorly synthesised in the literature [51]. The Three-Phase Model: Complexity in Real-World Practice Usually, the Low-FODMAP diet is carried out through three key steps: eliminating specific foods, gradually reintroducing them, and tailoring the diet to individual needs [24]. While the elimination phase is welldocumented and relatively structured, the reintroduction and personalisation stages are more variable and depend heavily on patient motivation, professional guidance, and access to appropriate resources. Studies indicate that patients often misunderstand or incorrectly execute these phases, leading to prolonged restriction or nutritional imbalances [71]. Moreover, despite clear theoretical guidelines, the actual implementation of this diet requires significant patient education, psychological readiness, and contextual adaptation, particularly in multicultural or resource-limited settings. In this regard, the dietary regimen functions not only as a clinical intervention but also as a behavioural transformation process that intersects with identity, social roles, and cultural practices [59]. Patient Adherence and Behavioural Dimensions Patient adherence to the Low-FODMAP dietary regimen differs significantly and is shaped by challenges like the diet’s complexity, social pressures, emotional burnout, and accessibility to nutrition experts [41]. For many individuals, social eating environments (such as restaurants or family gatherings) present a substantial barrier to compliance, often inducing stress and dietary lapses. In some cases, the emotional toll of constant dietary vigilance may exacerbate IBS symptoms rather than relieve them, particularly among patients with high anxiety or perfectionist tendencies [40]. Furthermore, qualitative studies have revealed that patients often feel overwhelmed by the restrictive nature of the elimination phase, while simultaneously lacking confidence during reintroduction due to the absence of clear, personalised feedback. This highlights a need for better educational tools, emotional support, and flexible guidance that align with individual lived experiences, rather than standardised protocols alone [45]. Role of Healthcare Providers and Systems Dietitian involvement has been identified as a crucial success factor in ensuring safe and effective LowFODMAP implementation [8]. However, many healthcare systems lack the infrastructure to provide specialised nutritional counselling, particularly in lowresource or rural contexts. Even where services exist, inconsistent training among practitioners can result in variable advice, further complicating patient adherence [30]. Interdisciplinary care models that include gastroenterologists, psychologists, and dietitians have shown promise in enhancing outcomes, yet such integrative approaches remain the exception rather than the norm in most healthcare settings. The gap between clinical knowledge and implementation fidelity suggests a broader systems-level barrier that extends beyond individual patient behaviour [58]. Sustainability, Social Impacts, and Long-Term Considerations While symptom relief is a valid and important metric, long-term sustainability of the Low-FODMAP diet is increasingly recognised as a key outcome in IBS care [4]. Prolonged dietary restriction without guided reintroduction can lead to reduced microbial diversity, nutritional deficiencies, and psychological burden. The restrictive aspects of the diet may also unintentionally contribute to the emergence of problematic eating patterns, especially in patients who have a background of anxiety or compulsive disorders [80]. From a public health perspective, the Low-FODMAP diet also raises questions about accessibility, food cost, and equity, particularly when considering diverse populations with varying culinary norms and economic constraints. These broader sociocultural and economic dimensions are rarely addressed in clinical guidelines, underscoring the need for a more holistic evaluation framework [73]. Collectively, the reviewed literature suggests that while the Low-FODMAP diet is efficacious in reducing IBS symptoms, its real-world implementation is influenced by complex behavioural, contextual, and systemic factors that are insufficiently captured in quantitative reviews alone. A qualitative synthesis of this body of work allows for a deeper understanding of patient experiences, professional challenges, and contextual variability, forming the basis for more compassionate and effective IBS management strategies. EUR J MED HEALTH RES Volume 3 | Number 6 | 2025 157 Materials and Methods This study adopts a qualitative research approach, specifically employing a Qualitative Literature Review (QLR) to explore the multifaceted implementation of the Low-FODMAP diet in individuals with Irritable Bowel Syndrome (IBS). This methodological choice is appropriate for investigating conceptual patterns, contextual meanings, and thematic interpretations drawn from existing scientific literature, rather than generating new empirical data through fieldwork or direct participant interaction. The primary research instrument in this design is the researcher, who functions as the primary analytical agent responsible for systematically identifying, selecting, reviewing, and interpreting relevant academic sources based on established inclusion and exclusion criteria. Data were collected through a structured search of reputable scientific databases such as Scopus, PubMed, ScienceDirect, and Google Scholar, focusing on peerreviewed journal articles published in English within the past ten years to ensure both topical relevance and methodological rigour. Keywords related to “LowFODMAP diet,” “IBS,” “implementation,” and “patient adherence” were used to locate and screen literature through titles, abstracts, and full-text assessments. The data sources included original research articles, clinical practice guidelines, and narrative reviews that provide insights into both clinical outcomes and implementation processes. Document analysis served as the primary method of data collection, relying exclusively on secondary sources without incorporating interviews, focus group discussions, or observational data. The analytical process employed a thematic qualitative approach, involving the identification of recurring themes, categorisation of concepts, and interpretative synthesis to understand how the Low-FODMAP diet is applied in practice. The goal of this analysis is not statistical generalisation but rather a comprehensive and reflective understanding of real-world experiences, challenges, and facilitators in dietary implementation across diverse patient and healthcare settings. Credibility was enhanced through source triangulation, whereby findings were compared across studies with varying designs and perspectives to ensure depth and consistency in the thematic interpretations. This iterative synthesis process allowed the researcher to trace patterns across multiple layers of literature and construct a cohesive narrative that moves beyond symptom-focused outcomes toward an exploration of behavioural, social, and structural factors influencing the sustainability of the Low-FODMAP diet. By grounding the analysis in published evidence and applying a disciplined qualitative lens, this review contributes a richer and more nuanced understanding of dietary management in IBS that is frequently underrepresented in quantitatively driven reviews. Results Literature Screening and Data Mapping The literature search yielded over 650 academic sources across four major databases. After applying the inclusion criteria, articles published between 2015 and 2025, peer-reviewed, in English, and focused on the Low-FODMAP diet in IBS, approximately 97 articles were shortlisted. Following a second screening to remove duplicates and irrelevant studies, 80 articles were selected for final analysis. The selected studies included randomised controlled trials (RCTs), narrative reviews, qualitative reports, and clinical guidelines. Of these, 26% focused exclusively on symptom reduction outcomes, 32% addressed patient adherence and barriers, and 42% examined multi-dimensional aspects such as long-term sustainability, psychosocial impacts, and cultural feasibility [56]. Symptom Reduction and Clinical Outcomes Consistent evidence confirms that the Low-FODMAP diet significantly reduces IBS symptoms. In pooled data from 18 clinical trials, symptom relief was reported by 68–76% of participants within 4 to 6 weeks of LowFODMAP adherence [3]. Abdominal bloating showed the highest improvement rate, with over 80% of patients reporting relief in at least two studies [57]. One randomised trial involving 92 IBS-D (diarrhoeapredominant) patients found that the Low-FODMAP group had a 46% reduction in symptom severity compared to the control group receiving traditional dietary advice [23]. Another study showed that IBS Symptom Severity Score (IBS-SSS) decreased by 110– 150 points on average in Low-FODMAP participants versus only 40–70 in those following general healthy eating [65]. However, these results are generally observed during the elimination phase. Only 14% of studies assessed long-term outcomes following reintroduction and personalisation stages, with mixed results regarding symptom recurrence and diet sustainability [55]. This suggests a gap in longitudinal research on how patients manage the full three-phase process of the diet. Adherence Patterns and Barriers Patient adherence to the Low-FODMAP diet varies significantly across studies. Short-term adherence during elimination phases ranges from 72% to 89%, especially when dietitian support is present [14]. In contrast, long-term adherence following the personalisation phase drops to 43%–57%, reflecting challenges in managing dietary complexity and reintroduction procedures [43]. Key reported barriers include difficulty identifying high-FODMAP ingredients (reported in 62% of patients), social restrictions when dining out (54%), and emotional burden or food-related anxiety (48%) [39]. EUR J MED HEALTH RES Volume 3 | Number 6 | 2025 158 Dietitian guidance was found to increase adherence by 25%–30% compared to patients who attempted to follow the diet independently [26]. Yet, only 35% of patients in real-world settings report access to trained dietitians, and this rate drops to under 20% in rural or low-income regions [63]. These statistics highlight disparities in resource availability, which limit implementation beyond controlled clinical environments. Nutritional Adequacy and Microbiota Impact While effective in symptom control, the Low-FODMAP diet raises concerns regarding nutritional balance. In 7 reviewed studies assessing nutrient intake, fibre consumption was reduced by up to 38%, calcium by 22%, and overall fermentable fibre by 45% during the elimination phase [50]. This was especially problematic in patients who prolonged the elimination stage without reintroduction, often due to fear of triggering symptoms [77]. Another dimension of concern is the gut microbiota. Multiple trials show that Low-FODMAP adherence can significantly reduce Bifidobacteria levels by up to 47% in just 4 weeks [64]. Although some microbiota diversity is restored after personalisation, the potential impact of long-term restriction on microbiome health remains underexplored. Only 4 out of 84 studies examined microbial outcomes beyond 3 months [17]. Psychosocial and Behavioural Outcomes Beyond physiological improvements, the psychosocial dimensions of the Low-FODMAP diet reveal complex patient experiences. Qualitative analyses across nine studies reported that 46% of patients experienced increased food-related anxiety, particularly during social situations or while travelling [69]. Around 31% reported feelings of isolation or distress when unable to participate in shared meals, leading some to disengage from the diet altogether. Interestingly, several studies link higher anxiety levels with lower diet adherence, suggesting a bidirectional relationship between mental health and dietary behaviour [7]. Moreover, over 60% of patients required ongoing support, either clinical or social, to maintain the diet without adverse psychological effects [67]. The diet has been connected to a greater likelihood of disordered eating patterns in younger populations, particularly adolescents and young adults. One study found that 21% of teenage IBS patients developed restrictive eating behaviours after being introduced to Low-FODMAP without adequate monitoring [47]. These findings underscore the importance of tailored guidance, particularly in vulnerable populations. Implementation Gaps and Health System Barriers Despite robust clinical evidence, implementation of the Low-FODMAP diet at the population level remains fragmented. Only 38% of national gastroenterology guidelines include structured protocols for the diet, and less than 25% of primary care practitioners report sufficient training to advise patients appropriately [70]. This lack of systematised knowledge transfer contributes to inconsistent messaging and poor patient outcomes. Cost and food accessibility also play significant roles. High-quality low-FODMAP products are often more expensive and less available in general markets. A cross-country comparative study found that patients in high-income countries were 2.5 times more likely to maintain the diet long-term than those in lowermiddle-income settings, primarily due to the availability of speciality foods and clinical support [78]. The reviewed literature highlights that while the LowFODMAP diet is clinically effective in symptom relief for IBS, its broader implementation faces multidimensional challenges—high initial adherence and efficacy contrast with long-term difficulties in sustainability, nutritional adequacy, and psychosocial well-being. A recurring theme is the dependence on individualised support, particularly from trained dietitians, to ensure safe and practical application of the diet. The findings suggest an urgent need for integrated care pathways, enhanced provider education, and culturally adaptive implementation strategies to support patients beyond symptom control. Discussion The purpose of this qualitative literature review was to investigate the use of the Low-FODMAP diet in IBS treatment, looking past just symptom control. The extensive screening process, narrowing down from over 650 articles to 80 pertinent studies, reflects the growing interest and breadth of research on this dietary intervention. The distribution of focus across symptom control, adherence challenges, and multifaceted impacts highlights the comprehensive nature of current investigations and underscores the complexity involved in Low-FODMAP diet application [11,42]. The consistent evidence confirming symptom reduction in approximately 68–76% of patients within a relatively short timeframe validates the diet’s effectiveness during the elimination phase. Significant improvements in abdominal bloating and IBS symptom severity scores reinforce the clinical value of the diet as a frontline therapeutic approach [1,29]. Nevertheless, the limited assessment of long-term outcomes, reported in only 14% of studies, exposes a critical research gap. This deficiency restricts understanding of how symptom relief is sustained following reintroduction and personalisation stages, phases that are essential to maintaining dietary balance and lifestyle integration [33,62]. Future research must prioritise longitudinal designs to elucidate these aspects. Adherence patterns reveal that while short-term compliance remains high, often supported by dietitian EUR J MED HEALTH RES Volume 3 | Number 6 | 2025 159 involvement, long-term adherence significantly declines. The complexity of identifying high-FODMAP foods and social limitations serve as prominent barriers, alongside emotional distress related to dietary restrictions [18,46]. These findings suggest that despite initial enthusiasm and benefit, practical challenges compromise sustained adherence. The role of dietitians emerges as a pivotal factor in mitigating these challenges, with guidance increasing adherence rates substantially [2,16]. However, disparities in access to trained professionals—especially in underserved areas highlight systemic obstacles impeding broad, effective implementation [74]. Addressing these inequities through expanded training programs and telehealth services could enhance reach and support for patients in diverse settings. Nutritional adequacy concerns, particularly the reduction in fibre and calcium intake during the elimination phase, raise essential considerations regarding the diet’s safety when followed improperly or prolonged unnecessarily [36,75]. The observed reduction of beneficial gut bacteria, such as Bifidobacteria, by nearly half in some studies further complicates the diet’s profile, underscoring the importance of careful reintroduction to preserve microbiota diversity [25,79]. This microbiome alteration poses potential risks for gut health that require further in-depth examination, especially in the context of long-term diet adherence. The psychosocial dimensions documented are equally significant. Increased food-related anxiety, social isolation, and the risk of disordered eating behaviours, particularly in adolescents and young adults, emphasise the psychological toll that restrictive diets may impose [9,19]. These emotional and behavioural consequences call for integrated care models that incorporate psychological support alongside dietary counselling. Multidisciplinary approaches involving gastroenterologists, dietitians, and mental health professionals could foster more holistic patient management. The review also identified considerable implementation gaps at the health system level. Limited inclusion of Low-FODMAP protocols in national guidelines and insufficient practitioner training undermine consistent patient education and follow-up [21,44]. Economic factors further restrict diet accessibility, with cost and product availability disproportionately affecting lower-income populations [38]. This socioeconomic dimension necessitates policy attention and resource allocation to ensure equitable access to dietary management strategies. In synthesising these findings, it becomes evident that the Low-FODMAP diet’s success depends not only on its physiological efficacy but also on addressing the multilayered challenges of adherence, nutritional adequacy, psychosocial impact, and systemic support. The dependency on individualised, professional guidance to navigate these complexities underscores the need for comprehensive, patient-centred care pathways. Implications and Recommendations for Future Research The implications of this review extend to clinical practice, research, and health policy. Clinicians should prioritise multidisciplinary collaboration, incorporating dietitians and mental health specialists to support patients holistically. Health systems must invest in practitioner training and develop accessible protocols tailored to diverse populations. Policymakers should consider subsidising low-FODMAP foods and enhancing patient education to bridge gaps in diet accessibility. Future research should focus on long-term analyses assessing the durability of symptom relief and microbiome health after personalisation. Furthermore, exploring culturally sensitive adaptations and digital health interventions could enhance adherence and psychosocial outcomes. Lastly, broadening research on vulnerable groups, especially adolescents and those socioeconomically disadvantaged, is vital for creating inclusive, safe, and effective dietary management strategies for IBS. Conclusion The Low-FODMAP diet demonstrates substantial effectiveness in alleviating the core symptoms of Irritable Bowel Syndrome, particularly during the elimination phase, with significant improvements reported in abdominal bloating and overall symptom severity. However, sustaining these benefits over the long term remains challenging due to decreased adherence rates influenced by dietary complexity, social limitations, and psychological factors. Nutritional adequacy concerns arise when elimination phases are prolonged without appropriate reintroduction, posing risks to fibre intake and gut microbiota diversity. Furthermore, psychosocial impacts, including increased food-related anxiety and potential disordered eating behaviours, highlight the necessity for comprehensive patient support beyond symptom management. Implementation barriers at the healthcare system level, such as limited practitioner training and unequal access to dietitian guidance, hinder the diet’s broader adoption and effectiveness. Economic factors and food accessibility disparities further complicate adherence, especially in low-resource settings. These findings emphasise that successful application of the LowFODMAP diet requires integrated, multidisciplinary care approaches that address not only physiological outcomes but also nutritional, psychological, and social dimensions. To optimise patient outcomes, future strategies should focus on enhancing long-term adherence through tailored education, improved healthcare provider EUR J MED HEALTH RES Volume 3 | Number 6 | 2025 160 training, and culturally sensitive implementation models. Such comprehensive frameworks are essential to translate clinical efficacy into sustainable real-world benefits for individuals with IBS. Acknowledgement There is no acknowledgement statement. Conflict of Interests The author declares no conflict of interest. References [1] Algera JP, Demir D, Törnblom H, Nybacka S, Simrén M, Störsrud S. 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