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This work is licensed under a Creative Commons Attribution 4.0 International License. The license permits unrestricted use, distribution, and reproduction in any medium, on the condition that users give exact credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if they made any changes. Original article Rethinking Bioethics as a Response to Global Biological Consciousness Raúl Isea Fundación Instituto de Estudios IDEA, Hoyo de la Puerta, Baruta, Venezuela Abstract Humanity is continually threatened by global pandemics exemplified by the Black Plague, the Spanish flu, and recently COVID-19 which reveal a continual absence of concern in real-time prevention. To forecast biological threats in the future and spur proactive human response we introduced the term Global Biological Consciousness (GBC). The GBC requires an Extended Bioethics a dynamic ethical framework for conscious management mediated by the GBC. This perspective will enable preventive actions and will seek global biological resilience through the algorithmic responsibility of AI and systemic justice which will be explained in the work. The GBC through Extended Bioethics will provide an ability to analyze biological data as it occurs using AI and quantum computing anticipate outbreaks before they happen and attenuate their effects. This creates a new ethical contract for all humankind as it coexists in a biological world. Keywords: Extended Bioethics, Global Biological Consciousness, Resilience, Ethical contract, Pandemic. Received: 03.10.2025 Revised: 03.11.2025 Accepted: 05.11.2025 Published: 11.11.2025 Funding: This research did not receive any financial support. Conflict of interest: The authors declare no conflict of interest. How to cite: Isea R. Rethinking Bioethics as a Response to Global Biological Consciousness. J Clin Pract Med Res, 2025;1(3):7-9. DOI: 10.59324/jcpmr.2025.1(3).02 Introduction The 21st century displays remarkable developments in biotechnology. For example, CRISPR offers an ability to edit genes in a way that could potentially treat diseases for which there is no cure [1]. However, this kind of technology does raise ethical debates related to the genetic manipulation of individuals suffering from such illnesses [2]. In parallel, artificial intelligence (AI) is a contributing force in the medical era [3], from automating diagnostics and discovery of new drugs to neurotechnology advancements creating a new capacity for intervention and analysis that create difficulties for existing ethical frameworks [4]. Bioethics is at a crossroads, as we will see. The classical definition relates to the methodical examination of human conduct in life sciences and health care, with respect to the moral values and principles developed in a small number of people [5]. Nevertheless, this vision, which was designed with a narrow view on certain problems, reveals its inadequate basic ability to respond as a whole, particularly at the global level. Bioethics must respond, even change, and embrace a comprehensive perspective that embraces the interconnectedness of the world and the rapidly advancing status of modern science [6], as evidenced by global health problems [7], and the scope and complexity of new technology [6]. This necessity arises because we have a shortcoming in our synergistic capacity to respond to a world health threat through a realtime biological surveillance system. We can continue to develop technology; however, without the shared situational awareness of biological information around the globe, we remain open to outbreaks of infectious diseases that can rapidly escalate into pandemics, as we have seen historically. For this reason, this paper suggests the necessity to introduce the Global Biological Consciousness (GBC) and extended bioethics as an important way to bridge this gap. Why the Need for Global Biological Consciousness? From the earliest time frame, humanity has faced pandemics, initially caused by a lack of understanding of pathogens, and later because we could not react to epidemic outbreaks promptly, so we have paid a very high price for this ignorance. We must remember the Black Death (14th century) that wiped out communities and which did not have any knowledge, at that time, of either microbiology or the mechanisms of contagion [9]. Then there was the Spanish Flu (1918), which also, and notwithstanding scientific advances at that time, had no epidemic surveillance system in place, and millions lost their lives to viral contagion; more people died than died from either of the World Wars [10]. And now we continue to live through the COVID-19 pandemic [11]. It is unclear if humanity is able to withstand pandemics through natural evolution, acquired immunity, and reactive actions that tend to be more like some desperate tool rather than a conscious planned survival strategy. In fact, the COVID-19 pandemic is the most significant reminder of this permanent vulnerability in the modern period. Notwithstanding our advances, a biologically imposed perception system does not exist to detect a virus in real time, let alone to document its emergence or track its spread across the world. In tandem with a conceptual vacuum or void, the world demonstrated itself incapable of an organized and coordinated response, resulting in devastating human and economic consequences. These historical and recent failures emphasize the urgent need to move beyond this collective blindness.
Journal of Clinical Practice and Medical Research (ISSN 3083-7146) Volume 1 | Number 3 | November-December 2025 8 As such, it is worth noting that Global Biological Consciousness (GBC) is defined as a global system adapted to timely detect biological threats globally, as well as be able to conduct analysis using classic and quantum computing systems with novel affinities toward identifying and monitoring biological threats at the molecular level, as well as independently and combined epidemiological and environmental factors that occur on a global level. GBC is a necessary tool to enable moving to a transition toward a proactive response, and represents a new crossroads in the human species' biological destiny. Global Biological Consciousness (GBC) Global Biological Consciousness (GBC) is an action that we must put in place after the previous pandemics. It is more than just an epicenter study; it is a cognitive capacity possessed by humanity that gives us the conscious vision of our biological health status, collectively. This means that now, with advanced AI and Quantum computing, GBC can collect, analyze, and connect large volumes of genomic, epidemiological, and environmental observations to recognize patterns and know threat trajectories that humanity could never have thought without the pandemic results of COVID-19 [12]. Simultaneously, an egalitarian consciousness must move ahead with the development of our early threat detection vehicle, considering this is not a vehicle for governing humanity, but rather, one to intervene before the threat becomes unmanageable for containment. To demonstrate the effectiveness of this preemptive system, I will use the following scenario: Imagine this scenario, where outbreaks of flu occur as unrelated cases in different sectors of a region. Health decision-makers could not conceptualize the outbreaks until after a significant time lag, but GBC would analyze all of this. This would be made evident with GBC, even recommending to look at the genomics of the virus, the contagion speed in the population moving thereafter, and even climatic conditions, while interpreting the consequences of decisions made. GBC would determine if they are independent outbreaks or show a likelihood of a future epidemic and closure, using the data accumulated with respect to latitude and longitude, to narrow the group into or towards population hot spots, therefore seeking to demonstrate critical points or systemic vulnerabilities before a recognized crisis becomes another pandemic. GBC combines the powerful computational capacity of artificial intelligence (including quantum processing of massive and complex data) to interpret, decide, and even recommend governmental agendas to contain a biological threat. Nevertheless, such overwhelming power requires a new moral framework. This will lead to an extension of the idea of bioethics, let's call it Extended Bioethics, where responsibility in the use of AI becomes paramount, and social justice is highlighted globally and not by groups or countries, but rather on an inclusive whole. Implications of Global Biological Consciousness The GBC will offer an effective counter to any biological threat posed to society, thereby reducing its impact. The use of surveillance measures supervised by the frameworks defined by an Extended Bioethics will ensure that humanity does not suffer the repercussions of another pandemic. The most important outcome of this system will be its proactive rather than reactive nature. Early detection of emerging pathogens and their transmission patterns will allow for the implementation of preventive and containment measures long before an uncontrollable outbreak occurs, and as a result will significantly reduce both human and economic costs that have come to characterize large scale responses such as prolonged isolation and disruption to social life. On the flip side, GBC could, if necessary, assist in smartly distributing and mobilizing critical resources for health, such as vaccines, treatments, and Personal Protective Equipment (PPE) in an efficient manner to the actual need, and avoiding excessive or inequitable access. Expanding the Concept of Bioethics The ideal of a pandemic-free world requires an ethical scheme that seems unrealistic for the whole world to fit into. The reality is that we are not able to effectively utilize the upper limits of state-of-the-art biotechnologies and surveillance systems due to constraints of a traditional vision. There is, therefore, a need to rethink using a global and dynamic ethical framework of bioethics that conceptualises human health as a connected and complex system with no boundaries of information. This articulates the need to potentially define an Extended Bioethics on the basis of four key moral foundations: • Conscious Management: It is essential that humanity navigate its biological and technological trajectory with an open mind to accept all contexts of responses and ensure free information access to the earliest identification of any outbreak or epidemic. • Global Biological Resilience: The extended objectives of bioethics are to identify, contain, and withstand disease to enhance science and its ability to recover biological integrity as it maintains life. • Algorithmic Responsibility: The ethical obligation that must guarantee that the evolution of AI systems perform in an open and fair way that includes systems of oversight and assessment. Due to the potential of biased algorithms that can impact human health, Extended Bioethics will make GBC is not a "black box" but can guarantee decisionmakers are fair and responsible in political decisions to mitigate such diseases. • Systemic Justice: An analysis and reporting of a global perspective on policies that will foster a fair distribution of benefits and resources among all countries and communities that require involvement to address biological threats is achieved largely due to Extended Bioethics. The GBC will not only identify biological threats. This extension will allow bioethics to keep pace with technological progression so that Global Biological Consciousness can not only be a detection system but also assist in resource distribution more equitably in a manner that provides advice and warnings but will not be able to make such decisions on its own. Conclusions Humanity has navigated a trajectory that bears witness to historical negligence in the face of pandemics (from the Black Death to the Spanish Flu and the most recent pandemic, SARS-CoV-2). This trajectory guides this paper to a radical solution: the Global Biological Consciousness (GBC). A vision that harnesses the 21st century's technological advances to ensure our survival is not far from being a technological chimera. Realizing GBC requires a transformation of the moral compass. Traditional bioethics focused on individuals and a social group's reactive and normative about what is moral is perhaps not adequate under the complications of a future where one person's health is inextricably connected to the health of humanity. Consequently, the articulation of bioethics is not only a term or word change, but ensures that bioethics become a new ethical contract for humanity in a world collapsed into a global era. This new Extended Bioethics will advocate for a conscientious management of our biological destiny that transcends the lessons of historical neglect, utilizing algorithmic accountability, and is
Journal of Clinical Practice and Medical Research (ISSN 3083-7146) Volume 1 | Number 3 | November-December 2025 9 contextualized within a new systemic justice. These foundational principles translate into concrete policy recommendations. Policy recommendations drawn from the GBC and Extended Bioethics include building GBC globally, creating bi-lateral and multi-lateral agreements for unrestricted biological information, and developing ethical and legal policy for AI to establish rights of fairness, truth, and openness. Additionally, it will be important to establish appropriate governance that promotes equitable access to resources (e.g., vaccines, treatments) as well as resources that can support multinational scientific collaboration, ensuring GBC supports the capacity of an Early Warning System and that, at a larger scale, it can support health social justice throughout the world. At the heart of all of this discussion and these plans, the GBC is a reflection of the aspiration for a civilization that will adapt in modern times, under the supporting umbrella of Extended Bioethics, to guarantee a dynamic and global ethical standpoint. This is the way towards a future where fear is met by vision and vulnerability is replaced by collective wisdom. In conclusion, the Extended Bioethics is the evolving and global ethical framework, necessary for Global Biological Consciousness (GBC), which establishes a new moral contract for humanity. The role of the Extended Bioethics is to ethically manage the biological fate of the species, and relies on Global Biological Resilience, Algorithmic Responsibility, and Systemic Justice for protecting interdependent health in a global age. References [1]. Jasieniecka A, Domingues I. CRISPR-Cas9 and Its Bioinformatics Tools: A Systematic Review. Curr Issues Mol Biol. 2025 Apr 27;47(5):307. doi: 10.3390/cimb47050307. [2]. Ayanoğlu FB, Elçin AE, Elçin YM. Bioethical issues in genome editing by CRISPR-Cas9 technology. Turk J Biol. 2020 Apr 2;44(2):110120. doi: 10.3906/biy-1912-52. [3]. Isea R. Artificial Intelligence Can Diagnose any Disease from the Data of an Electrocardiogram. J Biomed Sci Biotech Res. 2024. 2(1): 14. doi: doi.org/10.61440/JBSBR.2024.v2.03 [4]. Shepherd V. Advances and challenges in conducting ethical trials involving populations lacking capacity to consent: A decade in review. Contemp Clin Trials. 2020 Aug;95:106054. doi: 10.1016/j.cct.2020.106054. [5]. Cruz-Coke R. Introducción de la bioética en la medicina contemporánea [Introduction to bioethics in contemporary medicine]. Rev Med Chil. 1995 Mar;123(3):363-7. Spanish. [6]. Isea R. Biotechnology 2.0. Journal of Current Scientific Research 2023. 2(2):1-7. doi:10.14302/issn.2766-8681.jcsr-23-4811. [7]. Isea R. We Continue to Battle with Diseases that are Difficult to Diagnose and Cure in the 21st Century. Mathews J Pharma Sci. 2023, 7(3):22. [8]. Di Costanzo A, Spaccarotella CAM, Esposito G, Indolfi C. An Artificial Intelligence Analysis of Electrocardiograms for the Clinical Diagnosis of Cardiovascular Diseases: A Narrative Review. J Clin Med. 2024 Feb 11;13(4):1033. doi: 10.3390/jcm13041033. [9]. Cohn SK Jr. Epidemiology of the Black Death and successive waves of plague. Med Hist Suppl. 2008;(27):74-100. [10]. Parmet WE, Rothstein MA. The 1918 Influenza Pandemic: Lessons Learned and Not-Introduction to the Special Section. Am J Public Health. 2018 Nov;108(11):1435-1436. doi: 10.2105/AJPH.2018.304695. [11]. Vonderschmitt J, Wöhlke S, Schicktanz S. Scarce resources, public health and professional care: the COVID-19 pandemic exacerbating bioethical conflicts - findings from global qualitative expert interviews. BMC Public Health. 2023 Dec 13;23(1):2492. doi: 10.1186/s12889-02317249-4. [12]. Isea R. Comparative analysis of ENSO influence in classical and hybrid quantum epidemiological models for COVID-19 contagion analysis in Venezuela. J Clin Pract Med Res, 2025;1(2): 6-12. doi: 10.59324/jcpmr.2025.1(2).02