Bioactive and agroindustrial potential of Amazonian fruit species: a review

Cogen Food & Ag icul u e ISSN: 2331-1932 (Online) Jou nal homepage: www. and online.com/jou nals/oa a20 Bioac i e and ag oindus ial po en ial o Amazonian ui species: a e iew Lice h Na alia Cuélla Ál a ez, Juliana Ma ía Ga cía-Chacón, F ancisco J. He edia & M. Lou des González-Mi e To ci e his a icle: Lice h Na alia Cuélla Ál a ez, Juliana Ma ía Ga cía-Chacón, F ancisco J. He edia & M. Lou des González-Mi e (2025) Bioac i e and ag oindus ial po en ial o Amazonian ui species: a e iew, Cogen Food & Ag icul u e, 11:1, 2451062, DOI: 10.1080/23311932.2025.2451062 To link o his a icle: h ps://doi.o g/10.1080/23311932.2025.2451062 © 2025 The Au ho (s). Published by In o ma UK Limi ed, ading as Taylo & F ancis G oup Published online: 15 Jan 2025. Submi you a icle o his jou nal A icle iews: 984 View ela ed a icles View C ossma k da a Full Te ms & Condi ions o access and use can be ound a h ps://www. and online.com/ac ion/jou nalIn o ma ion?jou nalCode=oa a20 Food Science & Technology | Re iew ARTicle Cogen Food & Ag iCul u e 2025, Vol. 11, no. 1, 2451062 Bioac i e and ag oindus ial po en ial o Amazonian ui species: a e iew lice h na alia cuélla Ál a eza† , Juliana Ma ía ga cía-chacóna† , F ancisco J. he ediab and M. lou des gonzález-Mi e b ag upo de in es igación en P oduc os na u ales Amazónicos - giP onAZ, uni e sidad de la Amazonia, Flo encia, Colombia; bFood Colou and Quali y labo a o y, Facul ad de Fa macia, uni e sidad de Se illa, Se illa, Spain ABSTRACT i s high biodi e si y makes he Amazon ain o es a s a egic place o ca y ou biop ospec ing o ui and plan species wi h nu i ional, bio unc ional, and echnological alue. This e iew highligh s some Amazonian ui s such as açaí (Eu e pe ole acea), a azá (Eugenia s ipi a a), camu-camu (My cia ia dubia), canangucha (Mau i ia lexuosa), cocona (Solanum sessili lo um), and u a caima ona (Pou ouma cec opii olia), which dese e and need u he and deepe explo a ion o hei chemical composi ion, bioac i e p ope ies, and po en ial applica ions wi hin he ood indus y, especially hose g own in he colombian Amazon egion. The e o e, his a icle aims o con ibu e o he ob en ion and o mula ion o new and inno a i e ood p oduc s ha can inc ease he shel li e o ui s and p ese e hei bioac i e p ope ies, and in some cases, imp o e hei senso y accep ance. Addi ionally, i iden i ies he challenges in he p oduc ion and ma ke ing chain as a s a egy o p omo e he consump ion and comme cializa ion o hese Amazonian ui s, o e ing oppo uni ies o esea ch and de elopmen . 1. In oduc ion The Amazon egion, spanning 7.4 million km2 o Sou h Ame ica, cons i u es 4.9% o he con inen al a ea o plane ea h and co e s po ions o Boli ia, B azil, colombia, ecuado , guyana, Pe u, Su iname, and enezuela [comisión económica pa a Amé ica la ina y el ca ibe (cePAl), 2013]. Renowned o i s ege al biodi e si y, he egion se es as a i al hub o esea ch on bioac i e compounds and he po en- ial de elopmen o inno a i e ood p oduc s, enhancing he alue o edible ui s h i ing in i s high- empe a u e, acidic soil, and humid en i on- men . Since he p e-columbian pe iod, amazonian ui s ha e been o g ea social and economic impo - ance, wi h indigenous communi ies adi ionally using hem as cosme ics, ood, heal h-p omo ing sou ces, and o cons uc ion and ha ching (Bussmann & Paniagua Zamb ana, 2012). in ecen yea s, ui s such as açaí (Eu e pe ole acea), a azá (Eugenia s ipi a a), camu-camu (My cia ia dubia), canangucha (Mau i ia lexuosa), cocona (Solanum ses- sili lo um), and u a caima ona (Pou ouma cec opii o- lia), ha e eme ged as p ominen sou ces o no el na u al heal h ea men s and economic po en ial. They a e ecognized o hei nu i ional, phy ochem- ical, and bioac i e composi ion, including hei bio- unc ional p ope ies o he p e en ion o ch onic diseases like cance , ca dio ascula a lic ions, and me abolic synd ome diso de s (de A aújo e al. 2021; de Fá ima Rod igues e al. 2024; ga cía-chacón e al., 2022; Souza e  al., 2023; Tauchen e  al., 2016). in coun ies such as colombia, na ional policies and e o s by local a me s and p oduce s in he Amazon egion, speci ically in he e i o ies o Amazonas, caque á, guainía, gua ia e, Pu umayo, and aupés, ha e been ocused on e adica ing illici c ops and encou aging p oduce s o in eg a e he men ioned ui species, along wi h cacao (Theob oma cacao) and copoazú (Theob oma g andi- lo um), in o he comme cial chain, in o de o © 2025 he Au ho (s). Published by in o ma uK limi ed, ading as aylo & F ancis g oup CONTACT M. lou des gonzález-Mi e mi e @us.es Food Colou and Quali y lab., Á ea de nu ición y B oma ología, Facul ad de Fa macia, uni e sidad de Se illa, 41012 Se illa, Spain † hese au ho s collabo a ed equally on he wo k. h ps://doi.o g/10.1080/23311932.2025.2451062 his is an open Access a icle dis ibu ed unde he e ms o he C ea i e Commons A ibu ion license (h p://c ea i ecommons.o g/licenses/by/4.0/), which pe mi s un e- s ic ed use, dis ibu ion, and ep oduc ion in any medium, p o ided he o iginal wo k is p ope ly ci ed. he e ms on which his a icle has been published allow he pos ing o he Accep ed Manusc ip in a eposi o y by he au ho (s) o wi h hei consen . ARTICLE HISTORY Recei ed 22 oc obe 2024 Re ised 31 decembe 2024 Accep ed 2 Janua y 2025 KEYWORDS Eu e pe ole acea; Eugenia s ipi a a; My cia ia dubia; Mau i ia lexuosa; Solanum sessili lo um; Pou ouma cec opii olia SUBJECTS F ui & ege ables; Food chemis y; Pigmen s 2 l. n. cUÉllAR Ál AReZ eTAl. p omo e new social and economic oppo uni ies as pa o he bioeconomy o he sou he n egion o he coun y (cuella Al a ez e  al., 2017; Fan inelli e  al., 2017; he nández e  al., 2007). howe e , he lack o knowledge among p oduce s and consum- e s ega ding cul i a ion managemen , p ocessing, and de i ed p oduc s poses a signi ican obs acle o p omo ing hei cul i a ion o na ional and in e na ional ade in a sus ainable manne (cuella Al a ez, 2023). Mo eo e , he consump ion o hese ui s is limi ed by hei high pe ishabili y, wi h an a e age shel li e no exceeding 7 days, and hei senso y accep ance, as hey o en p esen bi e and highly acidic no es in hei la o p o ile (ga cía chacón, 2023). on he o he hand, many e o s ha e been con- duc ed o de elop new ood p oduc s ocused on educing he pe ishabili y o he ui species p e i- ously s a ed while enhancing hei accep ance and p ese ing hei unique la o s, a ac ing a en ion om he scien i ic, academic, and ood indus y sec o s (Sousa e  al., 2023). a ious ag oindus ial app oaches ha e been implemen ed, employing d ying and e men a ion p ocesses, esul ing in ood p oduc applica ions such as ice c eams, yogu s, blended juices, unc ional be e ages, bak- e y p oduc s, among o he s (conceição e al., 2019; linha es e al., 2020; P ecision Repo s, 2023; San os e  al., 2022). Addi ionally, ui by-p oduc s such as seeds, seed coa s, peel, and he mos edible pa o he ui , he pulp, ha e been employed as ing edi- en s in he bio unc ional and in eg al alo iza ion o aw ma e ial s udies o each ui (da Sil ei a e  al., 2019; 2019; Ma os e  al., 2021; Sil a nascimen o e al. 2023). due o his, i is expec ed ha a p ocess o gaining ecogni ion in local ma - ke s and he g ow h o hei comme cializa ion chains h oughou he en i e Amazon ain o es would be s eng hened, enhancing he supply and sus ainable p oduc ion o hese opical wild ui s (cuella Al a ez, 2023). Thus, he aim o his e iew is o highligh he economic po en ial p esen ed by ui species such as E. ole acea, E. s ipi a a, M. dubia, M. lexuosa, S. ses- sili lo um, and P. cec opii olia, na i e o he Amazon ain o es , emphasizing he mos impo an aspec s o hei bioac i e composi ion, bio unc ional p ope - ies, and ag oindus ial applica ions. Th ough his e iew, i is expec ed o con ibu e o he ob en ion and o mula ion o new ood p oduc s ha inc ease he shel li e o he ui s, main ain hei bioac i e p ope ies, and imp o e hei cus ome senso y accep ance. Addi ionally, i aims o iden i y global challenges o inc ease awa eness, consump ion, ma - ke ing, and p oduc ion o hese ui s among he inhabi an s wi hin and beyond he Amazonian egion. 2. Economic and p oduc i e po en ial o Amazonian ui s The Amazon egion has pe manen and wild c ops, wi h 15% o he a ea being occupied by ui ees as shown in Figu e 1. F ui ees con ibu e o he biodi- e si y o his ain o es and a e ecognized o hei signi ican economic po en ial ( a gas Tie as e  al. 2018). These ees possess cha ac e is ics ha make hem p omising candida es o sus ainable cul i a ion, as hey can play a ole in bo h conse ing and es o - ing ecosys ems, as well as con ibu ing o ood secu- i y and nu i ion. Addi ionally, hei ui s could ha ness economic, biochemical, and ag oindus ial bene i s, he eby eme ging in o luc a i e global ma - ke s (lagneaux e  al., 2021). Fo his eason, he cha - ac e iza ion o hei edible ui s including species like Eu e pe ole acea, Eugenia s ipi a a, My cia ia dubia, Mau i ia lexuosa, Solanum sessili lo um, and Pou ouma cec opii olia, coupled wi h he esea ch o hese ou aspec s—biochemical composi ion, bio unc ional p ope ies, s udies on bioaccessibili y/bioa ailabili y, and de elopmen o ood p oduc s—holds po en ial o p omo ing hese c ops as esh o p ocessed ui , he eby expanding he local and egional ma ke oppo uni ies and a ge consume p e e ences (Figu e 1). Fu he mo e, hei ag onomic cha ac e is ics enable bo h he ui and i s o en unde u ilized by-p oduc s o exhibi economic g ow h and in eg al alo iza ion o he en i e Amazon egion and he coun ies wi hin i (Sil a da cos a e al. 2021). indeed, he comme cializa ion o ce ain Amazonian ui s as men ioned abo e, can con ib- u e o he p o ec ion o ag obiodi e si y, and expand hei bio unc ional and en i onmen al ben- e i s, he eby impac ing he bioeconomy o he biome. in his g oup o ui s, he e a e species such as açaí (Eu e pe ole acea Ma .), which is a palm ee species om he amily o A ecaceae and is mainly ound in he Amazon basin om B azil, colombia, enezuela, and Pe u. each plan o ms clus e s o up o 20 s ems, yielding 120 kg o ui /be ies annually. The edible pa s o he be ies a e pulp and peel, ep esen ing 7% o 25% o he o al E. ole acea weigh (de oli ei a & Schwa z, 2018). in ac , E. ole acea pulp is he mos consumed and comme cialized pa o he ui . The main impo e is he Uni ed S a es, wi h app oxima ely 77% o he o al expo ed des ined o no h Ame ica (Amo im cogenT Food & AgRicUlTURe 3 e al. 2024). Meanwhile, B azil is he la ges expo e o E. ole acea a ound he wo ld, wi h a highe p e - alence in he s a es o Amazonas, Pa á, Ma anhão, Tocan ins, and Amapá (Sil ei a e  al. 2023). The wo ldwide ma ke o his be y su passed a million dolla s in 2021 and is expec ed o con inue g owing s eadily a a a e o 10.25% annually un il 2027 (P ecision Repo s, 2023). o he ui s such as a azá (Eugenia s ipi a a Mc augh), also commonly known as ‘guayabo’, is a op- ical ui na i e o Sou h Ame ica. i is p ima ily ound in coun ies like colombia, ecuado , Pe u, and B azil, and is a ee o he My aceae amily o medium size, ha can g ow up o abou 5 o 10 me e s in heigh in wa m and humid clima es (Fe nández-T ujillo e  al., 2011). E. s ipi a a lea es a e Figu e 1. economic po en ial diag am o na i e Amazon ui s such as açaí (Eu e pe ole acea), a azá (Eugenia s ipi a a), camu-camu (My cia ia dubia), canangucha (Mau i ia lexuosa), cocona (Solanum sessili lo um), and u a caima ona (Pou ouma cec opii olia). 4 l. n. cUÉllAR Ál AReZ eTAl. abou 5–10 cm long, and hei lowe s a e small, whi e, o c eamy, and a e a anged in clus e s. They ha e p ominen s amens ha gi e he lowe a s ik- ing appea ance (he nández e  al., 2007). The E. s ipi- a a ui s a e ounded o a sligh ly o al shape, wi h a hin smoo h skin ha is yellow when ipe. The p o- duc ion o E. s ipi a a in coun ies like colombia has been concen a ed especially in he Sou h, wi h gua ia e, caque á, and Pu umayo e i o ies as main p oduce s wi h 200 hec a es plan ed, which is equi - alen o 840 ons pe yea . E. s ipi a a p oduc ion akes place yea - ound, wi h ha es peaks e e y wo mon hs. howe e , due o i s high pe ishabili y i s p oduc ion and p ocessing is limi ed o he ci ies o o igin o cul i a ion because he ui is a ely expo ed, as an al e na i e ozen pulp is expo ed (Fe nández-T ujillo e  al., 2011). Ano he opical ui belonging o he My aceae amily is camu-camu (My cia ia dubia (Kun ) Mc augh), ound speci ically in densely looded a eas o he Amazon ain o es (San os e  al. 2022). i s weigh is p ima ily composed o 60% pulp, 20% peel, and 20% seeds o he o al weigh , wi h he seeds being conside ed he non-edible pa o he ui (ga cía-chacón e al., 2023a). M. dubia has a p oduc- ion o 2,660 ui s/38 kg pe plan , and mo e han 42 ons pe hec a e. F om 2021, i is expec ed ha p o- duc ion o M. dubia will inc ease o 10 ons pe hec - a e in 10 yea s (Unidad de in eligencia come cial 2023). i s geog aphical dis ibu ion is cen e ed in he no he n B azil (in egions such as cacho o, Mapue a, Maçangana, and U upa); in Pe u (Amazonas, Ucayali, Ma añon, and Tig e), in he sou he n colombia and enezuela (caque á, Amazonas, Pu umayo, o inoco, Pa gueni, and cau a); as well as ecuado and Boli ia (cas o e  al., 2018). Mau i ia lexuosa l, na i e o he Amazon, is also pa o he Ace aceae amily. This ui is commonly known in colombia such as canangucha; in B azil such as bu i i; and as aguaje in Pe u (Resende e  al., 2019). M. lexuosa is a climac e ic ui , and an impo an species o palm ee na i e o Sou h Ame ica (Milanez e al., 2016). The e o e, i is a highly aded i em in local ma ke s o Boli ia, B azil, colombia, ecuado , guyana, Pe u, T inidad and Tobago, and enezuela (Sánchez-capa e  al. 2023). i plays a i al ole in hese ecosys ems and is aluable o local communi ies. This palm can each up o 35 m in heigh , wi h la ge lea es: 8–20 an-shaped lea es, and he yellow lowe s appea om decembe o Ap il. The ui s a e scaly b own, which g ow om decembe o June, and each clus e can con ain up o 500 ui s (Koolen e  al., 2018). The p oduc ion is 290 kg pe palm ee pe yea , pe hec a e can p o- duce app oxima ely 25 ons o ui pe yea (oli ei a e  al., 2024). M. lexuosa is composed o app oxi- ma ely 10% o 20% pulp, 15% o 20% peel, and 40% o 45% seeds ( h ee seeds pe ui ) (da Sil a San os e  al., 2010). As desc ibed by Sil a e  al. (2014), he peel is co e ed wi h homboidal, jux aposed, and eddish-b own scales. while he pulp, 46 mm hick, has an o ange colo wi h swee a oma, oily ex u e, and pas y consis ency. Ano he Amazon na i e ui , belonging o he Solanaceae amily, is Solanum sessili lo um dunal., commonly known by i s local names such as cocona in colombia, and cubi in B azil (Se eno e  al. 2018). gene ally, S. sessili lo um is no a e y well-known ui bu has a 97% edible po ion. i s consump ion is de e mined acco ding o he coun y o o igin and p oduc ion, o example in some local ma ke s o coun ies such as B azil, colombia, Pe u and o he s (dua e, 2011). This is a he baceous and ui ul sh ub plan , be ween 1 and 2 me e s high, bea ing climac- e ic ui , wi h an op imum ha es ime o 210 days a e lowe ing (oli ei a e al., 2024). The ui can be o al o ound and i is composed o 26.3% peel, and 9.7% seeds (Se eno e  al. 2018). i s ipening begins wi h a da k g een colo and ma u es wi h an o ange-yellow colo un il i u ns eddish o ange. indeed, he pulp is so , c eamy yellowish in colo , and no e y swee and sligh ly acidic; while i s peel is so , wi h 1 o 4 mm hick, and p esen s a bi e as e (Jiménez, 2018). Finally, he u a caima ona (Pou ouma cec opii olia Ma .), known as u illa o Amazon g ape ui belongs o he U icaceae amily. i ypically p oduces 83 ui s pe clus e , and 363 o 406 clus e s pe plan , wi h a o al weigh be ween 202–430 kg pe plan . gene ally, he pulp ep esen s 47.9%, he seeds 33%, and he peel 19% o he o al ui weigh (co poica 2001). P e iously, he ui was cul i a ed by he Ticuna indig- enous communi y in he wes e n Amazon egion (Ped osa e  al., 2018). nowadays, P. cec opii olia is ound in a eas wi h simila cha ac e is ics despi e hei eco ypic and geog aphic di e si y h oughou he Amazon egion such as colombia ( ichada, guainía, aupés, Me a, Amazonas, caque á, and Pu umayo), Pe u, ecuado and B azil (co poica 2001). The cul i a ion and p ocessing o o he Amazonian ui s, such as copoazú (Theob oma g andi lo um) o Tucumá (As oca yum aculea um), play a i al ole in s eng hening local p oduc ion chains and suppo ing small communi ies, he eby con ibu ing o he Amazon’s bioeconomy (da Sil a e  al., 2024; Mi anda e al., 2021). These ac i i ies also p esen oppo uni ies cogenT Food & AgRicUlTURe 5 o u he explo a ion and inno a ion in a eas such as chemical composi ion, medicinal p ope ies, and indus ial applica ions. This e iew, howe e , ocuses on ui s wi h he highes p oduc ion le els in he colombian Amazon, p io i izing hose wi h ib an pigmen a ion and heal h bene i s associa ed wi h ca o enoids and an hocyanins. i is wo h no ing ha pigmen s ha e no been iden i ied in copoazú pulp o Tucumá (Beze a e  al., 2024). By examining ui s like A azá, camu-camu, canangucha, cocona, and U a caima ona, his wo k seeks o showcase hei po en ial o inno a i e applica ions, pa icula ly wi hin he con- ex o he colombian Amazon egion. 3. Biochemical composi ion o Amazon ui s Amazonian ui s a e ecognized o hei complex p o ile o phy ochemicals, including i amins, a y acids, and seconda y me aboli es, p edominan ly led by phenolic compounds, o ganic acids, pig- men s, and e penoids. in addi ion, he amoun o hese compounds wi hin he ui s change acco d- ing o ac o s such as ipening s a e, geog aphical posi ion, o ype o soil (ne es e  al., 2015). Fu he mo e, hese biochemicals play a c ucial ole in bo h appea ance and senso y p ope ies o he ui s, alongside hei bioac i e p ope ies (cas o e  al., 2020; Sánchez-capa e  al. 2023). Unde - s anding he biochemical composi ion o Amazonian ui s is c ucial o op imizing hei nu i ional and senso y p ope ies ( la o and a oma), bio unc ional and heal h bene i s, shel -li e, and o e all quali y. Addi ionally, i has he po en- ial o d i e economic g ow h by iden i ying key compounds ha can be u ilized ac oss a ious indus ies, including ood, pha maceu icals, cos- me ics, and nu aceu icals. The ha nessing o hese compounds adds conside able economic alue o Amazon ui p oduc ion and p ocessing, s imula - ing ag icul u al inno a ion and economic g ow h in opical egions ( a gas Tie as e  al. 2018). As a na i e Amazonian ui , E. ole acea ui exhibi s a high con en o asco bic acid (125.87 ± 26.42 mg/100 g ui powde ) as shown in Table 1 (ca nei o e al. 2020). Addi ionally, compounds such as i amins, amino acids, mine als, and a y acids showed he g ea nu i ional alue o E. ole acea ui . Among hese compounds, o al die a y ibe (21.36 g/100 g o d ied ui ), α- ocophe ol (45.00 mg/100 g o d ied ui ), manganese (Mn) (32.300 mg/100 g o d ied ui ), i on (Fe) (2.059 mg/100 g o d ied ui ), and lipids (50.53 g/100 g o d ied ui ) exhibi ed he highes concen a ions. i is no ewo hy ha E. ole acea ui , coming om a palm ee, exhibi s a di e se a y acid p o ile comp ising 49.72% oleic acid, 25.31% palmi ic acid, and 13.51% lin- oleic acid (Bicha a & Rogez 2011). E. ole acea has been widely cha ac e ized in i s p o ile o bioac i e compounds, e en in i s non-edible pa s such as he seeds. in ac , wen y wo pheno- lics compounds we e iden i ied in he seeds, mainly la an-3-ols such as ca echins and p ocyanidins wi h a o al concen a ion o 19.1 ± 0.1 and 158 ± 1 mg ec/g o seeds ex ac , espec i ely (Ba os e  al. 2015). As men ioned be o e, he geog aphical loca- ion o he ui in luences he p o ile o bioac i e compounds and hei composi ion in he ui . in s udies om B azil, i was ound ha cyanidin 3- u inoside (1067 ± 125.95 μg/g eeze d ied pulp) is he main an hocyanin o he l4P16 ui geno ype pulp (ca alho e  al. 2017). This compound oge he wi h β-ca o ene (10.8 μg/g d ied weigh , dw) we e he only ype o pigmen s iden i ied in E. ole acea ui (Kang e  al., 2012). compounds such as anillic acid (20.40 ± 0.90 μg/g eeze d ied pulp) we e he mos abundan phenolic acid in he ui su passing e ulic acid, p-couma ic acid, o some hyd oxybenzoic acids (ca alho e al. 2017). Meanwhile, in d ied ui pulp om colombia, he o al amoun o phenolic compounds was epo ed as 56.1 ± 24.1 mg/100 g dw (ga zón e al., 2017). Fo he i s ime, hese indings iden i ied hyd oxybenzoic acids such as p o oca e- chuic acid hexoside, hyd oxy e uloyl quinic acid, syn- apoyl deoxyhexoside, sinapoyl hexoside, e ulic acid conjuga e 2, among o he s as pa o i s phenolic p o ile. likewise, p e ious epo s showed ha speci ic phenolic compounds in E. s ipi a a may a y depend- ing on ac o s such as a ie y, ipeness, and g owing condi ions (he nández e  al., 2007). The E. s ipi a a ui is composed o 8 o 10.75% p o ein, 5 o 6.5% ibe , and 69 o 72% o o he ca bohyd a es. in ac , o al die a y ibe is abou 39% d y ma e (Rogez e al., 2004) and he s a ch con en is signi ican , e en in ipe ui s (0.63%) (Filguei as e al., 2002). Meanwhile, he concen a ion o soluble suga s (glu- cose, uc ose, and suc ose) is low (Fe nández-T ujillo e  al., 2011). E. s ipi a a edible ac ion ui is a sou ce o mine als and i amins such as calcium (ca) (107.16 ± 1.54 m/100 g dw), po assium (K) (827.66 ± 14.51 m/100 g dw), and magnesium (Mg) (75.65 ± 1.28 mg/100 g dw); and in 100 g o ui he e a e app oxima ely 7.75 mg o i amin A, 9.84 mg o i a- min B1 and 7.68 mg o i amin c (de A aújo e  al., 2021; Rogez e al., 2004). in addi ion de A aújo e al. (2021a), de e mined 30 ola ile compounds in i s physicochemical p o ile, mainly lead by bicyclo(3.2.1) 6 l. n. cUÉllAR Ál AReZ eTAl. Table 1. Chemical p o ile o bioac i e compounds epo ed in Amazonian ui s. F ui Family ype o biochemical Biochemical compound name e e ence Açaí (Eu e pe ole acea Ma .) A ecaceae (Palm ee) An hocyanins Cyanidin 3-glucoside Cyanidin 3- u inoside (Ca alho e  al. 2017) epo ed in pulp and seeds Cyanidin-3,5-hexoside-pen oside Cyanidin-3-glucoside Cyanidin-3- u inoside Pela gonidin-3-glucoside Pela gonidin-3- u inoside Peonidin-3-glucoside Peonidin-3- u inoside (ga zón e al. 2017) P oan hocyanidins P oan hocyanidin ime P oan hocyanidin dime (Cos a e  al. 2021) Hyd oxybenzoic acids and de i a i es 3,4-dihyd oxybenzoic acid 4-Hyd oxybenzoic acid P o oca echuic acid hexoside P o oca echuic acid p-Hyd oxybenzoic acid Vanillic acid Sy ingic acid (Ca alho e  al. 2017) (ga zón e al. 2017) ellagi annins ellagic acid ellagic acid de i a i e (Schulz e  al. 2021) Hyd oxycinnamic acids and conjuga es Hyd oxy e uloyl quinic acid Sinapoyl hamnose 5-O-ca eoyl quinic acid p-Couma ic acid hexoside Ca eic acid Fe uloyl sinapic acid isome Fe uloyl hyd oxypy u ic acid Ca eoyl shikimic acid isome Fe uloyl sinapic acid isome Ca eoyl shikimic acid isome Sinapoyl hexose Fe uloyl de i a i e Sy ingic acid Fe ulic acid p-Couma ic acid (Ca alho e  al. 2017) Fla onoids Fla ones Apigenin-6,8-di-C-pen oside Apigenin-di-C-hexoside sul a e Apigenin Apigenin diglucoside Apigenin dihexoside Apigenin hexoside Apigenin glucoside Apigenin deoxyhexoside hexoside Apigenin-6,8-di-C-hexoside Apigenin-6-C-pen oside-8-C-hexoside A omadend in Ca echin Ch ysin dihyd okaemp e ol hexoside dihyd okaemp e ol ace yl hexoside dihyd olu eolin deoxyhexoside hexoside e yodic iol galangin Hispidulin Homoo ien in isoque ci in iso i exin iso i exin de i a e Kaemp e ol Kaemp e ol-3- u inoside Kaemp e ol deoxyhexosyl hexoside My ice in na ingenin o ien in Qd Que ce in Scopa in axi olin axi olin deoxyhexose axi olin de i a e (Cos a e  al. 2021) (Schulz e  al. 2021) (Con inued) cogenT Food & AgRicUlTURe 7 F ui Family ype o biochemical Biochemical compound name e e ence Fla an-3-ols isoo ien in o ien in Homoo ien in Vi exin lu eolin lu eolin deoxyhexosyl hexoside lu eolin diglucoside lu eolin-7-glucoside lu eolin-6-C-pen oside-8-C-hexoside isome lu eolin-6-C-pen oside-8-C-hexoside isome lu eolin-6-C-hexoside-8-C-pen oside lu eolin-6-C-hexoside lu eolin-8-C-hexoside lu eolin-C-hexoside-C-pen oside de i a i e Scopa in Ch ysoe iol Ch ysoe iol-7-glucoside Ch ysoe iol deoxyhesosyl hexoside Vi exin (Cos a e  al. 2021) Fla anones (+) Ca echin (+) epica echin axi olin deoxyhexose isome 1 axi olin deoxyhexose isome 2 axi olin Fla onols u in iso hamne in u inoside (ga zón e al. 2017) dehyd o la onols dihyd okaemp e ol isome 1 dihyd okaemp e ol isome 2 Fa y acids Palmi ic acid (C16:0) Palmi oleic acid (C16:1) es ea ic acid (C18:0) oleic acid (C18:1) linoleic acid (C18:2) α-linolenic acid (C18:3) Vacenic acid (C18:1 cis 11) (Bicha a & ogez 2011) Ca o enoids β-ca o ene o he cons i uen s α- ocophe ol Asco bic acid (Kang e  al. 2012) (Ca nei o e  al. 2020) A azá (Eugenia s ipi a a Mc Vaugh) My aceae Sh ub ee o ganic acids Malic acid Quinic acid (de A aújo e al. 2021a) epo ed in whole ui Phenolic acids gallic acid glucogallic acid Fla onoids Apigenin hexoside Apigenin hexoside ca ea e Me hylapigenin hexoside Ca echin dihexoside Ca echin hexoside galloca echin Kaemp e ol hyd oxy p opionyl hexoside Hexoside Kaemp e ol diace yl dicouma oyl hexose Kaemp e ol dihexoside lu eolin hexoside lu eolin malonyl dihexoside My ice in couma yl dihexoside hexoside Que ce in hexopy anosyl hexoside Ca o enoids lu ein Zeaxan hin Anhyd olu ein Anhyd ozeaxan hin Zeinoxan hin β-c yp oxan hin α-ca o ene β-ca o ene Zeinoxan hin my is a ea β-c yp oxan hin my is a e Zeinoxan hin palmi a e β-c yp oxan hin palmi a e lu ein dimy is a e lu ein my is oylpalmi a e (ga zón e al. 2012) Table 1. Con inued. (Con inued) 8 l. n. cUÉllAR Ál AReZ eTAl. F ui Family ype o biochemical Biochemical compound name e e ence Camu-camu (My cia ia dubia Mc Vaugh) My aceae (sh ub plan ) An hocyanins delphinidin-3-glucoside Cyanidin 3-O-glucoside (ga cía-Chacón e al. 2024) (F acasse i e  al. 2013) epo ed in pulp, peel and seeds. Fla onols My ice in 3-O-hexoside My ice in 3-O-pen oside Que ce in 3-O-hexoside Que ce in 3-o-pen oside My ice in ellagic acid de i a i es ellagic acid de i a i es ellagic acid hexoside ellagic acid pen oside ellagic acid desoxyhexoside ellagic acid ellagic ace yl hamnoside ellagic acid de i a i es gallic acid de i a i es gallic acid gallic acid de i a i e P oan hocyanidins galloca echin-galloca echin galla e-galloca echingalla e galloca echin-galla e galloca echin-galla e-dime o ganic acids Malic acid Asco bic acid (ga cía-Chacón e al. 2024) o al ca o enoids β-ca o ene (ne es e al. 2015) Canangucha (Mau i ia lexuosa l). A ecaceae Palm ee epo ed in whole ui Fa y acid Palmi ic acid, C16:0 S ea ic acid, C18:0 oleic acid, C18:1 linoleic acid, C18:2 linolenic acid, C18:3 eicosenoic acid, C20:1 (de Fá ima od igues e  al. 2024) lipid Me hyl palmi a e Palmi ic acid linoleic acid oleic acid S ea ic acid α- ocophe ol β- ocophe ol Ca o enoids lu ein α-ca o ene β-ca o ene 13-cis-β-ca o ene (dos San os e al., 2015) Fla onoids Que ce in-dihexoside My ice in glucu onid Me hylmy ice in-O-glucu onide Que ce in-O- u inoside Que ce in-O-glucoside Que ce in-3-O-glucu onide Kaemp e ol-3-O-glucoside Kaemp e ol-3-O-glucu onide na ingenin hexoside lu eolin-O-deoxyhexoside na ingenin Que ce in (Ab eu-na anjo e  al. 2020) An hocyanins Cyanidin-3- u inoside Cyanidin-3-glucoside Cocona (Solanum sessili lo um dunal.). Solanaceae Sh ub ee Ca o enoids β-ca o ene lycopene (Se eno e al. 2018) epo ed in whole ui Phenolic acids Ca eic acid Chlo ogenic acid p-Couma ic acid Fe ulic acid Salicylic acid Sinapic acid Sy ingic acid Vanillic acid ( auchen e  al. 2016) Phenolic compounds 5-ca eoylquinic acid n5,n10- bis(dihyd oca eoyl) spe midine n1,n5,n10- is(dihyd oca eoyl) spe midine ( od igues e al., 2013) Table 1. Con inued. (Con inued) cogenT Food & AgRicUlTURe 15 The bioaccessibili y and bioac i i y o he phenolic compounds p esen in E. s ipi a a we e e alua ed o he i s ime in a açá-boi, o he Amazon ui s, subjec ed o in i o gas oin es inal diges ion (de A aújo e  al., 2021b). The con en o o al phenolics and la onoids, and an ioxidan capaci y we e Table 2. Bioaccessibili y and bioa ailabili y s udies epo ed in Amazon ui s. F ui Biochemical Bioaccessibili y o bioa ailabili y alues e e ence E. ole acea Values o bioaccessibili y o nu ien s a ailable o be abso bed in he in es ine a e diges ion: To al phenolic compounds An hocyanins Vi amin C Mine als K, Mg, and Mn Ca and Cu P Zn Fe Mn An ioxidan capaci y 17–25% o açaí juice ( he mal o non- he mal) 14.39 % (p ≥ 0.045) o açaí pu ee 22.89%–32.27% (medium pu ple açaí pulp) 49% (ba ch cul u e e men a ion o açaí pulp) 40% o açaí juice (con ol) 8% o açaí juice (non- he mal) > 85% in açaí pu ple and whi e pulp 75%–80% in açaí pu ple and whi e pulp 30–82% in açaí pu ple and whi e pulp 55–63% in açaí pu ple and whi e pulp 25–18% in açaí pu ple and whi e pulp 53–72% in açaí pulp samples 8–17% in açaí pulp samples Values o bioac i i y o nu ien s a ailable wi h an ioxidan ac i i y a e in i o in es ine diges ion: dPPH: 2.26% AB S: 7.59% (linha es e al. 2020) (S a ussa e al. 2021) (Minighin e  al. 2019) (Alqu ashi e  al. 2017) (linha es e al. 2020) (linha es e al. 2020) (San os e al. 2021) (San os e al. 2021) (San os e al. 2021) (San os e al. 2021) (San os e al. 2021) (S. . oli ei a e al. 2019) (S. . oli ei a e al. 2019) (S a ussa e al. 2021) E. s ipi a a Phenolic compounds Mic opa icles (sp ay d ying: Sd and d ying chilling sp ay: SdC) (Chlo ogenic acid, u in, My ice in) showed good elease in he in es inal phase. (Quei oz de oli ei a e al. 2024) An ioxidan capaci y ORAC (23.66 µmol e g− 1). ( eyes-Al a ez & lana i 2023) Colo An ioxidan capaci y Polyphenol composi ion od p e ea men inc eased eezing a e (58 %). osmodehyd o- ozen a azá d ip-loss (40%). osmodehyd a ed samples p esen ed he highes discolo a ion le els. F eezing/ eeze d ying p e ea ed a azá imp o ed hem 16–48 %. F /lio ga e he bes esul s ega ding polyphenol con en (99–48 %). ( eyes-Al a ez e al. 2022) An ioxidan capaci y An ioxidan ac i i y (97–88 %) e en ion, whe eas od/lio p oduced he highes losses (59–84 %). osmo ic d ying: 63–85% (un ea ed ui ) and 72–90% (osmodehyd a ed a azá (odA)), whe eas he ac i i y e en ion le els we e 67–76% (un ea ed ui / odA). (de A aújo e al. 2021b) Phenolic compounds Fla onoids Phenolic acids An ioxidan capaci y A e in es inal phase diges ion: he seed had he highes amoun o o al phenolic compounds (-22.0%). he la onoid con en inc eased in he edible ac ion (92.8%). he phenolic acids educed. he seed showed he highes an ioxidan capaci y. (i u i e  al. 2021) To al polyphenols An ioxidan capaci y A e in i o gas oin es inal diges ion: he mic opa icles wi h mal odex in (1:9)-100 °C (61% o o al polyphenols) AB S (101%) F AP (85%) dPPH (31%) (de A aújo e al. 2021b) M. dubia Values o bioaccessibili y exp essed as (%) o eco e y a e in i o gas ic phase diges ion: (ga cía-Chacón e al. 2024) An ocyanins delphinidin-3-glucoside (d3g) max. o 70.59% in yogu wi h sp ay d ied powde a 180 °C using mal odex in and whey p o ein as ca ied agen s. Cyanidin 3-glucoside (C3g) max. o 67.90% in sp ay d ied powde a 150 °C using mal odex in as a ca ied agen . Malic acid max. o 90.84% in yogu wi h eeze d ied camu-camu (pulp and peel) Asco bic acid max. o 65.54% in eeze d ied camu-camu (pulp and peel). M. lexuosa Ca o enoids he ca o enoids p esen ed a cons an a e o deg ada ion du ing all ea men s. (de Souza Ca alho e  al. 2020) he bioaccessibili y was g ea e (highe ul asound ene gy densi y). (Be ni e  al. 2019) Phenolic compounds he bioaccessibili y o β-ca o ene was inc eased by di ec p ocessing o mic oemulsions (p < 0.01). (Pe ei a-F ei e e al. 2018) P o oca echuic acid Que ce in Apigenin Ca echin epica echin he bioaccessibili y was educed a e in i o simula ed gas oin es inal diges ion o pulp (38.7%), peel (18.7%), and endoca p (22.3%). S. sessili lo um no epo ed no epo ed no epo ed P. cec opii olia no epo ed no epo ed no epo ed 16 l. n. cUÉllAR Ál AReZ eTAl. de e mined, as well as pe o med hea map analysis o e alua e ela i e in ensi y o he phenolic com- pounds iden i ied by mass spec ome y analysis (eSi-lTQ-Xl-MS/MS), be o e and a e he diges i e p ocess. The seeds p esen ed he highes amoun o o al phenolic compounds, and his con en was educed a e diges ion, mainly in he in es inal phase (22.0%), while he la onoid con en inc eased in he edible ac ion (92.8%). Thus, i was possible o iden i y 9 la onoids and 8 phenolic acids in he edi- ble ac ion, while 10 la onoids and 7 phenolic acids we e iden i ied in he seed ex ac (Table 2). Addi ionally, au ho s epo ed ha a e in es inal diges ion, phenolic acids educed and la onoids inc eased hei ela i e in ensi y, and he seed showed he g ea es an ioxidan capaci y a e diges- ion. in ano he s udy (i u i e  al., 2021), mic opa i- cles wi h mal odex in we e p epa ed using sp ay d ying a 100 °c, in p opo ion (1:9), a high conse a- ion o bioac i i y was p esen ed a e gas oin es i- nal diges ion in i o, p ese ing 61% o he o al polyphenols and ABTS (101%), FRAP (85%) and dPPh (31%) o he an ioxidan capaci y (Table 2). Recen ly, Po o e  al. (2023) e alua ed he in luence o wo cold plasma echnologies, dielec ic ba ie discha ge plasma and glow discha ge plasma, on he phenolic p o ile o E. s ipi a a juice. The bioa ailabili y o phe- nolic componen s in he juice was enhanced by bo h plasma sys ems; he dielec ic ba ie discha ge plasma could boos his bioa ailabili y by as much as 201%. Rega ding s udies o bioaccessibili y in M. dubia, i has been epo ed ha phy ochemicals such as an hocyanins, asco bic acid, and malic acid exhibi bioac i e p ope ies associa ed wi h he ea men o non-communicable and ch onic diseases. ga cía-chacón e al. (2024) de e mined he impac o in i o gas oin es inal condi ions, including gas ic and in es inal phases, on hese biochemical com- pounds con en in sp ay d ied M. dubia ui and i s ood p oduc s (yogu s and g ape juice), while e alu- a ing hei bioaccessibili y. The wo p ima y an hocy- anins o M. dubia ui , p e iously men ioned (cyanidin-3-glucoside and delphinidin-3-glucoside), emained s able du ing he gas ic phase; howe e , hei maximum eco e y in he in es inal phase was below 70% o d ied M. dubia p oduc s and 10% o M. dubia be e ages. The asco bic acid con en dec eased du ing bo h he gas ic and in es inal phases, wi h a maximum eco e y o 65% o eeze d ied M. dubia, app oxima ely. Mo eo e , malic acid exhibi ed he highes eco e y alues, eaching up o a maximum o 90% o all M. dubia be e ages, demons a ing he high s abili y o he compound (Table 2). The inco po a ion o M. dubia in he be e - ages dec eased he bioaccessibili y o an hocyanins and asco bic acid due o hei p e ious elease in he ood ma ix, inducing oxida ion p ocesses. las ly, he sp ay d ying p ocess, mic oencapsula ing M. dubia bioac i e compounds wi h mal odex in and whey p o ein as ca ie agen s, induced highe eco e ies du ing gas oin es inal diges ion. in s udies o he e alua ion o he bioa ailabili y in M. lexuosa, Ba boza e  al. (2022) concluded ha p ocessing echniques could be in eg a ed (emulsi i- ca ion/s abiliza ion, and mic obial inac i a ion) o imp o e he bioa ailabili y o bioac i e compounds. Also, de Souza ca alho e  al. (2020) epo ed ha ca o enoids p esen ed a cons an deg ada ion a e du ing all ea men s ( i e le els o ene gy densi y: 0, 0.9, 1.8, 2.7 and 3.6 J.cm−3). howe e , bioaccessibili y was g ea e o ea men s using highe ene gy den- si y ul asound. The au ho s sugges ed ha he son- ica ion p ocess accele a es he up u e o he cell memb ane o he ui , eleasing bioac i e com- pounds. likewise, his ul asound p ocess inc eases he iscosi y o he ui juice, which in e up s he gas oin es inal eac ions o he compounds, and makes hem mo e bioa ailable. in o de o encapsula e and enhance he bioac- cessibili y o ca o enoids, Be ni e  al. (2019) o mu- la ed mic oemulsions using pi anga (E. uni lo a) and canangucha (M. lexuosa) ui s, due o hei ich lyco- pene and β-ca o ene con en . Fo his pu pose, high-speed homogeniza ion and ul asound wi h an ampli ude p obe we e employed, esul ing in an inc ease in he bioa ailabili y o ca o enoids. howe e , p ocessing also a ec s bioa ailabili y, as e idenced by he mic oemulsions being subjec ed o a dynamic gas oin es inal sys em simula ion mimicking human diges ion, which led o enhanced bioaccessibili y o bo h β-ca o ene and lycopene. Finally, Pe ei a-F ei e e  al. (2018) de e mined ha phenolic compounds iden i ied by hPlc in M. lexuosa (Table 2) showed educed bioaccessibili y a e in i o simula ed gas- oin es inal diges ion o ex ac s o pulp (38.7%), peel (18.7%) and endoca p (22.3%). The e o e, he au ho s sugges a comp ehensi e use o he ui , including i s esidues. Un o una ely, li e a u e da a do no p o ide in o - ma ion on he bioaccessibili y and bioa ailabili y o he S. sessili lo um and P. cec opii olia ui s. howe e , acco ding o he con en o bioac i e compounds epo ed in (Table 1), i is impo an o conduc u u e esea ch o de e mine he bioa ailabili y o hese compounds and o know he abso p ion o cogenT Food & AgRicUlTURe 17 nu ien s, in luenced by ac o s such as ea men pa ame e s (e.g. ime and in ensi y), empe a u e, and componen s a ec ing abso p ion (such as ood ma ix). 6. Use o me abolomic and omics ools analysis in he s udy de bioac i i y and composi ion o Amazonian ui s in he p e ious sec ions o his e iew, he com- pounds epo ed mos ly in ui s (Eu e pe ole acea, Eugenia s ipi a a, My cia ia dubia, Mau i ia lexuosa, Solanum sessili lo um, Pou ouma cec opii olia) ha e been men ioned, highligh ing he p esence o pig- men s (ca o enoids and an hocyanins). Addi ionally, nu i ional and b oma ological in o ma ion has been epo ed o he species subjec o his e iew, e al- ua ed using s anda d echniques. howe e , al hough esea ch has been ca ied ou on Amazonian ui s o cha ac e iza ion using in some cases hPlc-MS/MS echniques (un a ge ed me abolomic analysis), i is necessa y o con inue explo ing he biological, molecula and chemical po en ial, using ecen ad ances in omic echnologies, such as ansc ip om- ics, p o eomics and me abolomics; hese ools can o e a de ailed app oach o he physiology and me abolism o hese ui s, which a he ime o ca - ying ou his e iew had no been epo ed me ab- olomic da a analysis (Belay & James caleb, 2022). Fu he mo e, i should be no ed ha , by analyzing he gene ic exp ession o he ui , p o ein p oduc- ion and me aboli e p o iles, esea che s can gain a deepe unde s anding abou he mechanisms behind he changes in ui quali y, in luence o cul i a ion condi ions, composi ion, and e en i s ela ionship wi h he exp ession o genes associa ed wi h biolog- ical ac i i ies and p e en ion o pa hologies (Benlloch- Tinoco e  al., 2024). 7. Ad ancemen s in ood p oduc applica ions and shel -li e analyses: add essing pe ishabili y and pos -ha es con ol s a egies The inc ease in he consump ion o Amazonian ui s has been in luenced by hei nu i ional and bio unc- ional alue o hei phy ochemicals, gene a ing high expec a ions and economic po en ial o p oduce s in he egion and he coun ies ha a e pa o he Amazon ain o es (Todo o & Pie i, 2018). Addi ionally, hese compounds o e po en ial o use in o mula - ing and enhancing ood p oduc s wi h added alue including unc ional oods, ood addi i es, unc ional die p epa a ions and die a y supplemen s (Sánchez-capa e  al., 2023; conceição e  al., 2019). The d ying p ocess and he inco po a ion o ui ex ac s in se e al ood ma ices ha e been used as me hodologies in he de elopmen o ood p oduc s including ice c eams, cakes, cookies, swee s, jams, yogu s, alcoholic and non-alcoholic be e ages, choc- ola e p oduc s, a s, among o he s (conceição e  al., 2019; das chagas e al., 2021; San os e al., 2022, lim & lim, 2013, ca alho-Peixo o e  al., 2015). The ind- ings epo ed below highligh he po en ial o na i e Amazonian ui s as sou ces o bioac i e compounds o indus ial applica ions. A summa y o he main applica ions o he ui s is shown in Table 3. 7.1. Açaí (Eu e pe ole acea) in he li e a u e, one o he i s app oaches o e al- ua ing he impac o a ious polyphenolic co ac o s, ob ained om ooibos ea, on he s abili y and colo o an hocyanins in E. ole acea ui was ca ied ou by Pacheco-Palencia & Talco (2010). Au ho s examined di e en classes o polyphenols. Findings e ealed ha he p esence o la one-C-glycosides signi i- can ly imp o ed an hocyanin s abili y, namely cyanidin-3-glucoside and cyanidin-3- u inoside, and induced hype ch omic shi s, enhancing ed colo in ensi y, ac oss all ph (3.0, 3.5, and 4.0) and em- pe a u e condi ions (5, 20 and 30 °c). con e sely, phenolic acids and p ocyanidins showed no signi i- can e ec s. ex e nally added la one-C-glycosides, pa icula ly o ien in, isoo ien in, i exin, and iso i- exin, enhanced an hocyanin colo and s abili y, sug- ges ing hei po en ial as colo enhance s and s abilizing agen s in p oduc s con aining cyanidin glycosides, such as E. ole acea ui -based oods and be e ages. da Sil ei a e  al. (2019) e alua ed he impac o high-p essu e p ocessing and he mal pas eu iza ion on he bioac i e compounds and an ioxidan p ope - ies o E. ole acea juice. high p essu e p ocessing, especially a 500 MPa, p ese ed an hocyanins mo e e ec i ely compa ed o he mal pas eu iza ion, likely due o i s lowe he mal sensi i i y. These esul s sug- ges ha high p essu e p ocessing could p o ide E. ole acea juice wi h high unc ional quali y, o e ing po en ial bene i s o he ood indus y in p oducing E. ole acea ui -based o mula ions wi h enhanced ma ke alue. likewise, oli ei a e al. (2020), aimed o cha ac e ize he s uc u al and physicochemical p op- e ies, bioac i e compounds, and an ioxidan ac i i y o eeze-d ied E. ole acea pulp. The mo phology anal- ysis e ealed a coa se g anulome y, a sponge-like 18 l. n. cUÉllAR Ál AReZ eTAl. Table 3. Food p oduc s, d ying and s abili y p ocess o Amazonian ui s. F ui P incipal ood applica ions e e ence E. ole acea • impac o a ious polyphenolic co ac o s (whole ui ). • F ui -based p oduc packaging. • Pas eu ized juice (pulp). • F eeze d ied pulp. • Pulp unc ional be e age as an e gogenic aid o a hle es. • die a y supplemen . (Pacheco-Palencia & alco 2010) (Sil a nascimen o e al. 2023) (da Sil ei a e  al. 2019) (oli ei a e  al. 2020) (Ca alho-Peixo o e al. 2015) (ea ling e  al. 2019) E. s ipi a a • F eeze d ied and mic oencapsula ed powde s by sp ay d ying. • osmodehyd a ed, eeze d ying. • nec a o Apples supplemen ed wi h E. s ipi a a. • un il e ed alcoholic be e age. • Snack. (i u i e  al. 2021) ( eyes-Al a ez & lana i 2023) (Baldini e  al. 2017) (Souza e  al. 2020) (He nández e al. 2018) M. dubia • Yogu using ui peel, seeds and pulp ex ac . • F eeze d ied and mic oencapsula ed powde s by sp ay d ying using he ui pulp and peel. • g ape juice using pulp and peel powde s. • Blend juice wi h a s abili y es o bioac i e compounds. • Alcoholic e men a ion o yeas species and he ui pulp. • Whea lou wi h ui cop oduc (seeds, peels, and esidual pulp) o cookies bake y. • ice c eam using ui pulp. (Conceição e  al. 2019) (Fidelis, e  al. 2020) (ga cía-Chacón e al. 2024) (Vidigal e  al. 2011) (Ma os e al. 2021) (das Chagas e al. 2021) (Mau icio-Sando al e al. 2023) M. lexuosa • oil. • gel ilms. • Powde s by sp ay d ying (pulp and peel). • Supplemen die a y ibe and an ioxidan con en . (Pe ei a de oli ei a e al. 2022) (Anjos e al. 2023) (Comunian e  al. 2020) ( esende e  al. 2019) S. sessili lo um • Pos ha es (cold empe a u e). • Sou ce o pec in. • Func ional be e age (An ioxidan and lipid-lowe ing ac i i y) • nu aceu ical d ink nec a en iched wi h Chenopodium quinoa (o juela-Baque o e al. 2014) (Colodel & Pe kowicz 2019) (Va gas-A ana e al. 2024) (Quispe-He e a e al. 2022) P. cec opii olia • F ui sui able o jams, jellies, and wines. • Co ee subs i u e using he oas ed seeds (lim & lim 2013) (lim & lim 2013) cogenT Food & AgRicUlTURe 19 appea ance, and high po osi y. F eeze d ied E. ole acea pulp demons a ed inc eased wa e abso p ion and wa e solubili y indices wi h empe a u e, indica ing sui abili y o indus ial applica ions. The e o e, he consump ion o eeze-d ied ui pulp should be encou aged, along wi h i s u iliza ion by indus y o he de elopmen o new ood p oduc s. on he o he hand, he s udy o he impac o an E. ole acea unc ional be e age on a ious physiolog- ical pa ame e s du ing maximal eadmill unning was conduc ed by ca alho-Peixo o e al. (2015). The be e age, con aining 27.6 mg o an hocyanins pe dose, was designed as an e gogenic aid o a hle es. The esul s showed ha he unc ional be e age inc eased ime o exhaus ion du ing sho - e m high-in ensi y exe cise, a enua ed me abolic s ess induced by exe cise, educed pe cei ed exe ion, and enhanced ca dio espi a o y esponses. The s udy sugges ed ha he unc ional be e age could se e as a p ac ical and e ec i e e gogenic aid o imp o e pe o mance du ing high-in ensi y aining. 7.2. A azá (Eugenia s ipi a a) Acco ding o he iden i ied compounds lis ed in Table 1 and he known biological ac i i ies associa ed wi h he ui o E. s ipi a a, as well as i s high pe ishabili y, applica ions ha e been de eloped o help conse e he compounds ound in his Amazonian ui . one o he mos used echniques o he conse a ion o bio- ac i e compounds is sp ay d ying (Table 3) (Acos a- ega e  al., 2023; ga cía-chacón e  al., 2024; i u i e  al., 2021). in his con ex , i u i e  al. (2021) conduc ed esea ch aimed a p ese ing he bioac i - i y o E. s ipi a a using mic oencapsula ion ia sp ay d ying, coupled wi h di e en ial scanning calo ime y. They employed di e en wall ma e ials (mal odex in o gum a abic) and d ying empe a u es (100 o 120 °c). i was ound ha mic opa icles con aining mal odex in (1:9 a io) a a d ying empe a u e o 100 °c exhibi ed he mos e ec i e conse a ion o bioac i i y and phenolic composi ion. Quei oz de oli ei a e  al. (2024) de eloped mul i- laye mic opa icles o he elease o phenolic com- pounds using di e en encapsula ion p ocesses (sp ay d ying: Sd and sp ay d ying-cooling: Sdc) and wall ma e ials (ca á- oxo lou , A abic gum, a açá-boi ex ac ) o imp o e he s abili y and bioa ailabili y o phenolic compounds. The Sdc pa icles showed c ys- alline egions by X- ay di ac ion analysis and we e s able a ~47 °c. All samples showed good elease o phenolic compounds and an ioxidan ac i i y in in es inal diges ion es s. Fu he mo e, Reyes-Ál a ez & lana i. (2020) analyzed he e ec s o wa e ac i i y (aw), glass ansi ion empe a u e (Tg) and ype o ca ie (mal odex in-de10/gum a abic) on he colo o eeze-d ied E. s ipi a a and i s composi ion. The shel -li es o E. s ipi a a using he mal odex in and gum a abic sys ems (a 20 °c and aw = 0.11) we e 34 and 50 days, espec i ely. The au ho s sugges ed ha he unc ional po en ial o E. s ipi a a posi ions his ui as a p omising aw ma e ial o he de elop- men o new ood o mula ions. in addi ion, Reyes-Al a ez and lana i (2023) poin ed ou ha he high pe ishabili y o E. s ipi a a makes i challenging o indus ial applica ion and inco po a e in o new ood p oduc s. To add ess his issue, hey employed eezing and lyophiliza ion echniques along wi h osmo-dehyd a ion p e ea men in hei esea ch. The osmo-dehyd o eezing ea men was ound o enhance he bioaccessibili y o o al polyphenols. howe e , i led o a educ ion in he e en ion o an i- oxidan ac i i y, as shown in Table 2. Also, Fa ias e  al. (2023), applied cold plasma p ocessing on E. s ipi a a juice. The p ocessing condi ions and he ype o cold plasma sys em in luenced he concen a ion o o ganic compounds such as he dec ease in amino acids (43%), suga s (glucose (33%), uc ose (31%)), acids (malic acid (25%)); and inc eased suc ose (23%). howe e , when he plasma was used a 200 hz, he amino acid con en inc eased (9%). ne e heless, du ing he p oduc ion o powde s, undesi able changes in he colo o he dehy- d a ed p oduc s we e gene a ed. Mo eo e , Baldini e  al. (2017) o mula ed a d ink by adding amoun s o eeze d ied E. s ipi a a (Fd) o a comme cial apple nec a o e alua e he impac in nu i ional e ms (polyphenolic composi ion and an i- oxidan capaci y) and senso y pa ame e s. Apple nec- a supplemen ed wi h 10 g/l o Fd p esen ed he bes nu i ional and senso y p ope ies (highe poly- phenol con en and an ioxidan ac i i y). Finally, e - men a ion is a bio echnological p ocess ha inc eases he shel li e o ood p oduc s. Souza e al. (2020) hen in es iga ed he in luence o i e comme cial yeas s (Saccha omyces ce e isiae) and he il a ion p ocess on he chemical composi ion and an ioxidan capaci y o E. s ipi a a be e ages. As a esul , he be e age Biolie i o Bayanus (BBA) was ob ained (un il e ed: 13.9°gl). The be e age showed g ea e chemical com- posi ion and an ioxidan capaci y. 7.3. Camu-camu (My cia ia dubia) due o he high con en o polyphenols in he peel o M. dubia ui , his byp oduc was inco po a ed in o a dai y ood ma ix o enhance i s added alue 20 l. n. cUÉllAR Ál AReZ eTAl. and comme cial use (conceição e  al., 2019). The inco po a ion o M. dubia peel ex ac in o comme - cial yogu a a concen a ion o 0.5% did no signi i- can ly al e he nu i ional composi ion o he p oduc . howe e , Fidelis e  al. (2020) inco po a ed eeze d ied M. dubia seed ex ac in o yogu a con- cen a ions o 0.25, 0.50, 0.75, and 1.00 g/100 g. The samples we e analyzed o hei p oxima e composi- ion and he in i o an ioxidan ac i i y o he yogu samples was e alua ed using FRAP, dPPh, and FcRc assays, e ealing dose-dependen e ec s. yogu con- aining 0.25 g/100 g o seed ex ac was senso ially accep ed. These indings unde sco e he po en ial o inco po a ing na u al bioac i e- ich ex ac s in o dai y p oduc s like yogu , o e ing an al e na i e o syn he ic compounds. conside ing he high pe cep ibili y o his ui , mic oencapsula ed powde s o M. dubia pulp and peel we e also inco po a ed in o na u al and com- me cial yogu , as well as whi e g ape juice (15%). These powde s we e ob ained using mal odex in and whey p o ein as ca ie agen s, a empe a u es o 150 °c and 180 °c in a sp ay d ye . Addi ionally, eeze d ied M. dubia pulp and peel we e inco po- a ed a a concen a ion o 0.5%. The be e age sam- ples we e o i ied wi h bioac i e compounds such as an hocyanins, malic acid, and asco bic acid de i ed om he M. dubia ui . Acco ding o sen- so y analysis, yogu s con aining powde s wi h whey p o ein ecei ed be e o e all accep ance. Panelis s no ed ha inco po a ing M. dubia powde s in yogu imp o ed he swee ness-acidi y balance and led o highe accep ance. con e sely, samples wi hou whey p o ein showed be e accep ance in g ape juice due o a pe cei ed eshness sensa ion. Panelis s obse ed ha adding M. dubia powde s o yogu and g ape juice masked he high acidi y as e o he ui , he eby enhancing he senso y p ope ies and o e all quali y o he p oduc s (ga cía-chacón e  al., 2024). in o he in es iga ions, e men ed samples o eeze-d ied M. dubia pulp powde combined wi h soymilk exhibi ed highe inhibi o y ac i i y agains α-amylase and α-glucosidase enzymes compa ed o samples wi h sp ay d ied M. dubia powde s (sp ayed a an inle ai empe a u e o 120 °c, using di e en concen a ions (6%, 12%, and 18%) o gum a abic. Addi ion o 0.5% lyophilized M. dubia o soymilk and e men a ion wi h lac ic acid bac e ia doubled he inhibi o y ac i i y o α-amylase enzyme a e 72 hou s compa ed o he con ol, wi h u he enhancemen obse ed wi h he addi ion o 1% M. dubia powde s. Addi ionally, highe concen a ions o M. dubia powde s in soy- milk signi ican ly inc eased α-glucosidase inhibi- o y ac i i y h oughou he e men a ion pe iod, wi h peak ac i i y obse ed a e 48 hou s. This inc eased inhibi o y ac i i y was posi i ely co - ela ed wi h he high o al soluble phenolic con- en o M. dubia ui . The e men a ion app oach success ully imp o ed he bioac i e p o iles and heal h-p omo ing p ope ies o M. dubia ui and soymilk blends, p o iding p omising op ions o managing ea ly-s age Type 2 diabe es h ough die a y in e en ions (Fuji a e al., 2017). 7.4. Canangucha (Mau i ia lexuosa) Anjos e  al. (2023) de eloped a gela in-based ilm ha inco po a es M. lexuosa oil ex ac ed wi h p es- su ized p opane o he p ese a ion o an a isanal B azilian cheese. This assay e ealed a signi ican dec ease in he g ow h o Salmonella spp., P. ae ugi- nosa and E. coli du ing s o age o 14 days a 5 °c. The au ho s p oposed ha ilms o packaging can be gene a ed om M. lexuosa, helping o inc ease he shel li e o oods. Also, Resende e  al. (2019) e alua ed M. lexuosa by-p oduc lou s ( om peels and de a ed pulp) as a sou ce o die a y ibe and na u al an ioxidan s. The p esence o pec ic polysac- cha ides, a abinoxylans and xyloglucans was in e ed by he neu al monosaccha ide p o ile, as well as sig- ni ican amoun s o o al non-ex ac able p oan ho- cyanidins (nePA). The au ho s p oposed ha M. lexuosa lou s could be used as a supplemen due o hei die a y ibe and an ioxidan con en . conside ing he indus ial impo ance o M. lexu- osa oil, due o i s an ioxidan po en ial and high ca - o ene con en , Pe ei a de oli ei a e  al. (2022) p oposed a new high- ech p oduc composed o mic opa icles o M. lexuosa oil. in conclusion, he au ho s epo ed ha he combina ion in equi alen p opo ions o inulin and gum a abic is a iable al e na i e o he applica ion o M. lexuosa oil mic opa icles, o be inco po a ed in o hyd ophilic oods. howe e , oxida ion o ca o enoids du ing s o - age causes loss o colo in oods, making i di icul o use hese oils in ood p oduc s. Finally, comunian e  al. (2020) encapsula ed pequi oil and coencapsu- la ed pequi (C. b asiliense) and canangucha (M. lexu- osa) oils by emulsi ica ion using whey p o ein isola e as an emulsi ie in wo o ms, na u al (unhea ed) and hea ed, ollowed by eeze d ying. The o mula ions showed ca o enoid e en ion and oxida i e s abili y, indica ing ha oil emulsions ha e po en ial as ca i- e s o bioac i e compounds. cogenT Food & AgRicUlTURe 21 7.5. Cocona (Solanum sessili lo um) cu en ly, he e a e ew epo s o applica ions on de elopmen o new ood p oduc s o he S. sessili- lo um ui . howe e , aking in o accoun he an iox- idan e ec epo ed o he S. sessili lo um ui , Ba iuso e  al. (2015) e alua ed he e ec i eness o an ex ac ob ained om S. sessili lo um (Mce) as a po en ial inhibi o o choles e ol oxida ion unde hea ing condi ions. The au ho s epo ed ha Mce inhibi ed choles e ol deg ada ion (44% e sus 18% wi hou and wi h Mce, espec i ely) and conside - ably educed he o ma ion o choles e ol oxida ion p oduc s in he absence o docosahexaenoic acid (dhA). howe e , Mce was no e ec i e o choles- e ol oxida ion in he p esence o dhA. likewise, Mce showed i s an ioxidan e ec by p o ec ing dhA om deg ada ion. consequen ly, he au ho s sug- ges ed ha sol en - ee S. sessili lo um ex ac is a good ing edien o p o ec oods con aining highly polyunsa u a ed lipids om oxida ion and o p o ec choles e ol om oxida ion. Also, o p ese e he quali y o he S. sessili lo um ui , o juela-Baque o e  al. (2014) e alua ed some pos ha es o e a da ion ea men s, cold empe a- u e and waxing ea men s, in h ee mo pho ypes o he ipe ui (small- ounded, ellip ical, and gian ). As a ea men , hey applied a ho i ec® wax (1:3 / aqueous solu ion), which d ied na u ally. The ui s we e s o ed a low empe a u es (10 ± 2 °c a 85% ela i e humidi y Rh) and a oom empe a u e o he con ol (20 ± 2 °c a 75% Rh). The esul s indi- ca ed ha he ho i ec® coa ing did no imp o e he s o age pe o mance o S. sessili lo um ui . likewise, hey epo ed ha s o age a low empe a u e is an op imal ea men , which could imp o e he com- me cializa ion o S. sessili lo um ui . Mo eo e , a gas-A ana e al. (2024) de eloped a S. sessili lo um d ink ha showed a s a is ically signi ican lipid-lowe ing e ec (p < 0.05), wi h an a e age educ- ion o 41.52 mg/dl o o al choles e ol le els and 130.80 mg/dl o o al choles e ol le els o i- glyce ides. The au ho s sugges ed ha his d ink could be an al e na i e o he ea men o a he o- scle osis and p e en ion o ca dio ascula diseases. colodel & Pe kowicz (2019) ca ied ou he ex ac ion o pec in om S. sessili lo um. in his esea ch, pec in o med gels in acidic medium (ph 2.5–1.5) and 60% suc ose, and au ho s sugges ed ha pec in ex ac ed om S. sessili lo um could be used as an addi i e in acidic p oduc s wi h high con- en o soluble solids. Finally, Quispe-he e a e  al. (2022) de eloped a o mula ion wi h op imal unc ional and senso y cha ac e is ics, d ink wi h a p opo ion o 73% S. sessili lo um pulp and 7% cooked quinoa g ains. 7.6. U a caima ona (Pou ouma cec opii olia) The P. cec opii olia ui is swee and juicy, sui able o jams, jellies, and wines. howe e , i s delica e na u e and sho pos -ha es li espan p esen chal- lenges o ma ke ing. The swee lowe s a e also edi- ble and can be consumed aw o used o c ea e be e ages and wine. Addi ionally, he seeds, when oas ed, can se e as a co ee subs i u e (lim & lim, 2013). So a , o ou knowledge, he e a e no epo ed s udies ega ding he applica ion o he ui in a ood p oduc , chemical cha ac e iza ion, o mula ion, and i s s abili y. 8. Conclusions and u u e pe spec i es The Amazon egion boas s an unpa alleled di e si y o ui s, many o which emain unde u ilized o unknown ou side local communi ies. Amazon ui s such as E. ole acea, E. s ipi a a, M. dubia, M. lexuosa, S. sessili lo um, and P. cec opii olia ha bo a complex p o- ile o bioac i e compounds such as an ioxidan s, i amins, and phy ochemicals, which ha e been asso- cia ed wi h a ious heal h bene i s, including an ioxi- dan , an icance , and an i-obesi y p ope ies. The e o e, i is essen ial o p omo e he in eg a ion o inno a i e echnologies and sus ainable p ac ices in ui p o- cessing and alue chain managemen . due o he high pe ishabili y o he p io i ized Amazonian ui s in his e iew, signi ican e o s ha e been di ec ed owa ds he implemen a ion o conse a ion echnol- ogies aimed a p ese ing hei bioac i e compounds and bio unc ional p ope ies, such as eeze d ying o sp ay d ying. howe e , he e is a p essing need o u he imp o e p ocedu es o p e en he deg ada- ion o pigmen s and loss o colo , which a e dis inc- i e cha ac e is ics o hese Amazonian ui s. while mos epo s on an ioxidan ac i i y ha e u ilized con- en ional me hodologies (ABTS, FRAP, dPPh, oRAc), i is impe a i e o employ o he echniques o del e deepe in o he an ioxidan p ope ies o Amazonian ui s, p o iding mo e insigh s in o he oxida ion- educ ion mechanisms o he biocom- pounds p esen in hese ui s. Mo eo e , mos bioac- i i y analyses ha e been conduc ed in i o models. conside ing he p omising esul s al eady docu- men ed, i is necessa y o scale up samples de i ed om he ui s men ioned in his e iew o in i o 22 l. n. cUÉllAR Ál AReZ eTAl. analyses. This s ep is essen ial o alida ing he unc- ionali y o he highligh ed compounds wi hin each Amazonian ui in a physiological con ex and conse- quen ly, he a o emen ioned ui s hold signi ican economic and social alue. in conclusion, one s a - egy o enhance he p oduc i i y chain o hese spe- cies and ha ness hei bio unc ional, nu i ional, physicochemical (colo ), and senso y po en ial is o concen a e ongoing e o s on de eloping o design- ing new ood o mula ions ha inco po a e Amazonian ui s as aw ma e ials. This app oach would no only expand hei consump ion beyond cul i a ion a eas bu also con ibu e o he ag o-indus y o he de el- oping coun ies in he Amazon egion, os e ing eco- nomic g ow h and sus ainabili y. Acknowledgmen Au ho s a e hank ul o Minis e io de ciencia Tecnología e inno ación and Sis ema gene al de Regalias o colombia. Au ho s’ con ibu ions cuélla Ál a ez, lice h n: concep ualiza ion, me hodology, isualiza ion, alida ion, w i ing-o iginal d a p epa a ion. ga cía-chacón, J.M.: concep ualiza ion, me hodology, isu- aliza ion, alida ion, w i ing- o iginal d a p epa a ion. he edia, F ancisco J: supe ision, p ojec adminis a ion, w i ing – e iew & edi ing. gonzález-Mi e , M. lou des: supe ision, p ojec adminis a ion, w i ing – e iew & edi - ing. All au ho s ha e app o ed he inal manusc ip . Disclosu e s a emen no po en ial con lic o in e es was epo ed by he au ho (s). Funding This wo k was suppo ed by Minis e io de ciencia Tecnología e inno ación and Sis ema gene al de Regalias o colombia unde g an Beca de excelencia doc o al del Bicen ena io – co e i, and, FedeR, Ue. conseje ía de Uni e sidad, in es igación e inno ación de la Jun a de Andalucía, Spain (P ojec PAidi2021 PRoyeXcel_00578). Abou he au ho s Lice h Na alia Cuélla Ál a ez is Associa e P o esso in he chemis y P og am a he Uni e sidad de la Amazonia in Flo encia, caque á, colombia and leade o he Resea ch g oup in P oduc os na u ales Amazónicos – giPRonAZ. he main line o esea ch is Food chemis y and elabo a ion o oods om Amazonian ui s. Juliana Ma ía Ga cía-Chacón is a doc o in Food Science and Technology om he Uni e sidad nacional de colombia. She is a membe o he Resea ch g oup in P oduc os na u ales Amazónicos- giPRonAZ. he main esea ch a eas ocus on Bio unc ional oods, Bioac i e com- pounds in ood, and Senso y analysis. F ancisco J. He edia is Full P o esso in he depa men o nu i ion and B oma ology a he Uni e si y o Se ille and head o he esea ch g oup Food colou and Quali y labo a o y. he is an expe in colou Science and Food P ope ies (www.colo .us.es). M. Lou des González-Mi e is P o esso in he depa men o nu i ion and B oma ology a he Uni e si y o Se ille and a membe o he esea ch g oup Food colou and Quali y labo a o y. he main esea ch is ocused on he a eas o Food Science and Technology, colou Science, op ics and Senso y Analysis (www.colo .us.es). ORCID lice h na alia cuélla Ál a ez h p://o cid.o g/0000- 0003-0638-6998 Juliana Ma ía ga cía-chacón h p://o cid.o g/0000- 0002-8248-9107 F ancisco J. he edia h p://o cid.o g/0000-0002- 3849-8284 M. lou des gonzález-Mi e h p://o cid.o g/0000-0003- 0572-051X Da a a ailabili y s a emen da a sha ing is no applicable o his a icle as no new da a we e c ea ed o analyzed in his s udy. Re e ences Ab eu-na anjo, R., Pa edes-Mo e a, J. g., g anda-Albuja, g., i u alde, g., gonzález-Pa amás, A. M., & Al a ez-Sua ez, J. M. (2020). Bioac i e compounds, phenolic p o ile, an ioxi- dan capaci y and e ec i eness agains lipid pe oxida ion o cell memb anes o Mau i ia lexuosa l. ui ex ac s om h ee biomes in he ecuado ian Amazon. Heliyon, 6(10), e05211. h ps://doi.o g/10.1016/j.heliyon.2020.e05211 Acos a- ega, l., Ma ínez-Suá ez, J. F., Sánchez-ga zón, F. S., he nández-ca ión, M., & ne io, l. S. (2023). op imiza ion o he encapsula ion p ocess o cupuassu (Theob oma g andi lo um) pulp by sp ay d ying as an al e na i e o he alo iza ion o Amazonian ui s. LWT, 184, 114994. h ps://doi.o g/10.1016/j.lw .2023.114994 Alqu ashi, R. M., Ala i i, S. n., wal on, g. e., cos abile, A. F., Rowland, i. R., & commane, d. M. (2017). In i o ap- p oaches o assess he e ec s o açai (Eu e pe ole acea) diges ion on polyphenol a ailabili y and he subsequen impac on he aecal mic obio a. Food Chemis y, 234, 190–198. h ps://doi.o g/10.1016/j. oodchem.2017.04.164 Amo im, i. S., Amo im, d. S., godoy, h. T., Ma iu i, l. R. B., chis é, R. c., da Sil a Pena, R., Bogusz Junio , S., & chim, J. F. (2024). Amazonian palm ee ui s: F om nu i ional alue o di e si y o new ood p oduc s. Heliyon, 10(2), e24054. h ps://doi.o g/10.1016/j.heliyon.2024.e24054 And ade Júnio , M. c. d., Souza And ade, J., & Souza cos a, S. d. (2016). Biochemical changes o cubiu ui s cogenT Food & AgRicUlTURe 23 (Solanum sessili lo um dunal, Solanaceae) acco ding o di e en issue po ions and ipening s ages. Food and Nu i ion Sciences, 07(12), 1191–1219. h ps://doi. o g/10.4236/ ns.2016.712111 Anhê, F. F., nachba , R. T., a in, T. ., T o ie , J., dudonné, S., le Ba z, M., Feu y, P., Pilon, g., Ba bie , o., desja dins, y., Roy, d., & Ma e e, A. (2019). T ea men wi h camu camu (My cia ia dubia) p e en s obesi y by al e ing he gu mic obio a and inc easing ene gy expendi u e in die -induced obese mice. Gu , 68(3), 453–464. h ps:// doi.o g/10.1136/gu jnl-2017-315565 And ade, J. M. c. (2020). Bioac i e compounds om cubiu ui s (Solanum sessili lo um dunal). in h. n. Mu hy & . A. Bapa (eds.), Bioac i e compounds in unde u ilized ui s and nu s (pp. 437–441). Sp inge in e na ional Publishing. h ps://doi.o g/10.1007/978-3-030-30182-8_25 Anjos, h. A., cas o, d. A. M., dos San os-ne o, A. g., da luz, J. R. d., das g aças Almeida, M., lei e ne a, M. T. S., na ain, n., Pagani, A. A. c., F anceschi, e., he nández- Macedo, M. l., & lópez, J. A. (2023). gela in-based ilms inco po a ed wi h bu i i oil (Mau i ia lexuosa l.) as ac- i e packaging o a isanal cheese conse a ion. Bio esou ce Technology Repo s, 23, 101526. h ps://doi. o g/10.1016/j.bi eb.2023.101526 Baldini, T., ne i-numa, i., do Sac amen o, c., Schmiele, M., Bolini, h., Pas o e, g., & Bicas, J. (2017). elabo a ion and cha ac e i- za ion o apple nec a s supplemen ed wi h A açá-boi (Eugenia s ipi a a Mac augh—My aceae). Be e ages, 3(4), 59. h ps://doi.o g/10.3390/be e ages3040059 Ba boza, n. l., c uz, J. M. d. A., co êa, R. F., lama ão, c. ., lima, A. R., inada, n. M., Sanches, e. A., Beze a, J. d A., & campelo, P. h. (2022). Bu i i (Mau i ia lexuosa l. .): An Amazonian ui wi h po en ial heal h bene i s. Food Resea ch In e na ional (O awa, On .), 159, 111654. h ps:// doi.o g/10.1016/j. ood es.2022.111654 Ba ios, J., co de o, c. P., A is izabal, F., he edia, F. J., Mo ales, A. l., & oso io, c. (2010). chemical analysis and sc eening as an icance agen o an hocyanin- ich ex- ac om u a caima ona (Pou ouma cec opii olia Ma .) ui . Jou nal o Ag icul u al and Food Chemis y, 58(4), 2100–2110. h ps://doi.o g/10.1021/j 9041497 Ba iuso, B., Ma iu i, l. R. B., Anso ena, d., As iasa án, i., & B agagnolo, n. (2015). Solanum sessili lo um (mana‐cubiu) an ioxidan p o ec i e e ec owa d choles e ol oxida- ion: in luence o docosahexaenoic acid. Eu opean Jou nal o Lipid Science and Technology, 118(8), 1125– 1131. h ps://doi.o g/10.1002/ejl .201500285 Ba os, l., calhelha, R. c., Quei oz, M. J. R. P., San os-Buelga, c., San os, e. A., Regis, w. c. B., & Fe ei a, i. c. (2015). The powe ul in i o bioac i i y o Eu e pe ole acea Ma . seeds and ela ed phenolic compounds. Indus ial C ops and P oduc s, 76, 318–322. h ps://doi.o g/10.1016/j.ind- c op.2015.05.086c Belay, Z. A., & James caleb, o. (2022). Role o in eg a ed omics in un a elling ui s ess and de ence esponses du ing pos ha es : A e iew. Food Chemis y. Molecula Sciences, 5, 100118. h ps://doi.o g/10.1016/j. ochms.2022.100118 Benlloch-Tinoco, M., nuñez Ramí ez, J. M., ga cía, P., gen ile, P., & gi ón-he nández, J. (2024). Theob oma genus: explo ing he he apeu ic po en ial o T. g andi lo um and T. bicolo in biomedicine. Food Bioscience, 61, 104755. h ps://doi.o g/10.1016/j. bio.2024.104755 Be ni, P., Pinhei o, A. c., Bou bon, A. i., guima ães, M., cannia i-B azaca, S. g., & icen e, A. A. (2019). cha ac e i- za ion o he beha io o ca o enoids om pi anga (Eugenia uni lo a) and bu i i (Mau i ia lexuosa) du ing mic oemul- sion p oduc ion and in a dynamic gas oin es inal sys em. Jou nal o Food Science and Technology, 57(2), 650–662. h ps://doi.o g/10.1007/s13197-019-04097-7 Beze a, J. d A., co êa, R. F., Sanches, e. A., lama ão, c. ., S inghe a, P. c., Ma ins, e., & campelo, P. h. (2024). “cupuaçu” (Theob oma g andi lo um): A b ie e iew on chemical and echnological po en ial o his Amazonian ui . Food Chemis y Ad ances, 5, 100747. h ps://doi. o g/10.1016/j. ocha.2024.100747 Bicha a, c. M. g., & Rogez, h. (2011). Açai (Eu e pe ole acea Ma ius). Pos ha es Biology and Technology o T opical and Sub opical F ui s, 1, 27e. h ps://doi.o g/10.1533/9780857092762.1 Bussmann, R. w., & Paniagua Zamb ana, n. y. (2012). Facing global ma ke s – usage changes in wes e n Amazonian plan s: he example o Eu e pe p eca o ia Ma . and E. ole acea Ma . Ac a Socie a is Bo anico um Poloniae, 81(4), 257–261. h ps://doi.o g/10.5586/asbp.2012.032 c. And ade, M. S., J , And ade, J., S. cos a, S., & A. S. lei e, e. (2017). nu ien s o cubiu ui s (Solanum sessili lo um; dunal, Solanaceae) as a unc ion o issues and ipening s ages. Jou nal o Food and Nu i ion Resea ch, 5(9), 674– 683. h ps://doi.o g/10.12691/j n -5-9-7 ca nei o, A. P. d g., Aguia , A. l. l. d., gonzaga, M. l. d c., Soa es, d. J., Figuei edo, e. A. T. d., Sousa, P. h. M. d., & Figuei edo, R. w. d (2020). S abili y o bioac i e compounds, an ioxidan , and mic obiological ac i i y o açaí powde (Eu e pe ole acea Ma . Resea ch, Socie y and De elopmen , 9(7), e229973810.) h ps://doi.o g/10.33448/ sd- 9i7.3810 ca alho, A. ., Fe ei a Fe ei a da Sil ei a, T., Ma ie o, R. d A., Padilha de oli ei a, M. d S., & godoy, h. T. (2017). chemical composi ion and an ioxidan capaci y o açaí (Eu e pe ole acea) geno ypes and comme cial pulps. Jou nal o he Science o Food and Ag icul u e, 97(5), 1467–1474. h ps://doi.o g/10.1002/js a.7886 ca alho-Peixo o, J., Mou a, M. R. l., cunha, F. A., lollo, P. c. B., Mon ei o, w. d., ca alho, l. M. J. d., & Fa ina i, P. d T. . (2015). consump ion o açai (Eu e pe ole acea Ma .) unc- ional be e age educes muscle s ess and imp o es e o ole ance in eli e a hle es: A andomized con olled in e - en ion s udy. Applied Physiology, Nu i ion, and Me abolism = Physiologie Appliquee, Nu i ion e Me abolisme, 40(7), 725– 733. h ps://doi.o g/10.1139/apnm-2014-0518 cas o, J. c., Maddox, J. d., cobos, M., e al. (2020). Bioac i e compounds o camu-camu (My cia ia dubia (Kun h) Mc augh). in Re e ence se ies in phy ochemis y (pp. 329– 352). Sp inge in e na ional Publishing. h ps://doi. o g/10.1007/978-3-030-30182-8_21 cas o, J. c., Maddox, J. d., cobos, M., & imán, S. A. (2018). My cia ia dubia “camu camu”. F ui : heal h-p omo ing phy ochemicals and unc ional genomic cha ac e is ics. in B eeding and heal h bene i s o ui and nu c ops. inTech. h ps://doi.o g/10.5772/in echopen.73213 colodel, c., & Pe kowicz, c. l. d o. (2019). Acid ex ac ion and physicochemical cha ac e iza ion o pec in om cubiu (Solanum sessili lo um d.) ui peel. Food Hyd ocolloids, 86, 193–200. h ps://doi.o g/10.1016/j. oodhyd.2018.06.013 comisión económica pa a Amé ica la ina y el ca ibe (cePAl). (2013). Amazonia posible y sos enible. cepal y 24 l. n. cUÉllAR Ál AReZ eTAl. Pa imonio na u al. Re ie ed Ap il 12, 2024, om h ps://www.cepal.o g/si es/de aul / iles/news/ iles/ amazonia_posible_y_sos enible comunian, T. A., Sil a, M. P., Mo aes, i. c. F., & Fa a o-T indade, c. S. (2020). Reducing ca o enoid loss du ing s o age by co-encapsula ion o pequi and bu i i oils in oil-in-wa e emulsions ollowed by eeze-d ying: Use o hea ed and unhea ed whey p o ein isola es as emulsi ie s. Food Resea ch In e na ional (O awa, On .), 130, 108901. h ps:// doi.o g/10.1016/j. ood es.2019.108901 conceição, n., Albuque que, B. R., Pe ei a, c., co êa, R. c. g., lopes, c. B., calhelha, R. c., Al es, M. J., Ba os, l., & c F R Fe ei a, i. (2019). By-p oduc s o camu-camu [My cia ia dubia (Kun h) Mc augh] as p omising sou ces o bioac i e high added- alue ood ing edien s: Func ionaliza ion o yogu s. Molecules (Basel, Swi ze land), 25(1), 70. h ps://doi.o g/10.3390/molecules25010070 co poica, c. c. d. i. A. (2001). Especies p omiso ias de la Amazonia:conse ación, manejo y u ilización del ge moplasma. co po ación colombiana de in es igación ag opecua ia - AgRoSA iA. Re ie ed Ma ch 9, 2024, om h ps:// eposi o y. ag osa ia.co/handle/20.500.12324/30714 cos a, R., Aze edo, d., Ba a a, P., Soa es, R., guido, l. F., & ca alho, d. o. (2021). An iangiogenic and an ioxidan in i o p ope ies o hyd oe hanolic ex ac om açaí (Eu e pe ole acea) die a y powde supplemen . Molecules (Basel, Swi ze land), 26(7), 2011. h ps://doi.o g/10.3390/ molecules26072011 coyago-c uz, e., guachamin, A., illacís, M., Ri e a, J., ne o, M., Méndez, g., he edia-Moya, J., & e a, e. (2023). e alua ion o bioac i e compounds and an ioxidan ac i i y in 51 mi- no opical ui s o ecuado . Foods (Basel, Swi ze land), 12(24), 4439. h ps://doi.o g/10.3390/ oods12244439 c upi, P., Milella, R. A., & An onacci, d. (2010). Simul aneous hPlc-dAd-MS (eSi+) de e mina ion o s uc u al and geome ical isome s o ca o enoids in ma u e g apes. Jou nal o Mass Spec ome y: JMS, 45(9), 971–980. h ps:// doi.o g/10.1002/jms.1794 cuella Al a ez, l. n. (2023). Biop ospección de me aboli os secunda ios del u o A azá (Eugenia s ipi a a McVaugh), cul i ado en el depa amen o del Caque á, Colombia [doc o al disse a ion]. Uni e sidad de la Amazonia. cuella Al a ez, l., cuella Al a ez, n., galeano ga cia, P., & Suá ez Salaza , J. c. (2017). e ec o e men a ion ime on phenolic con en and an ioxidan po en ial in cupuassu (Theob oma g andi lo um (willd. ex Sp eng.) K.Schum.) beans. Ac a Ag onómica, 66(4), 473–479. h ps://doi.o g/10.15446/acag. 66n4.61821 da Sil a San os, R., de Souza, A. A., de Paoli, M. A., & de Souza, c. M. l. (2010). ca danol– o maldehyde he mo- se composi es ein o ced wi h bu i i ibe s: P epa a ion and cha ac e iza ion. Composi es Pa A: Applied Science and Manu ac u ing, 41(9), 1123–1129. h ps://doi. o g/10.1016/j.composi esa.2010.04.010 da Sil a, c. . A., Salimo, Z. M., de Souza, T. A., Reyes, d. e., Bassiche o, M. c., de Medei os, l. S., Sa im, M. A., de ca alho, J. c., gonçal es, J. F. c., Mon ei o, w. M., Ta a es, J. F., de Melo, g. c., da Sil a, F. M. A., Ba aglion, g. A., & Koolen, h. h. F. (2024). cupuaçu (Theob oma g andi lo- um): A mul i unc ional Amazonian ui wi h ex ensi e bene i s. Food Resea ch In e na ional (O awa, On .), 192, 114729. h ps://doi.o g/10.1016/j. ood es.2024.114729 da Sil a, F. c., Picada, J. n., Romão, n. F., Sob al, F. d o. S., lemos, d., Schons, S. d ., de Mello, T. l., Sil a, w. M., oli ei a, R. d S., lucas, c. P., Pe ei a, P., cha es, . c., Regina o, F. h., & Fe az, A. d B. F. (2019). An igeno oxic and an imu agenic e ec s o My cia ia dubia juice in mice submi ed o e hanol 28-day ea men . Jou nal o Toxicology and En i onmen al Heal h. Pa A, 82(17), 956– 968. h ps://doi.o g/10.1080/15287394.2019.1671279 da Sil ei a, T. F. F., c is ianini, M., Kuhnle, g. g., Ribei o, A. B., Filho, J. T., & godoy, h. T. (2019). An hocyanins, non-an hocyanin phenolics, ocophe ols and an ioxidan capaci y o açaí juice (Eu e pe ole acea) as a ec ed by high p essu e p ocessing and he mal pas eu iza ion. Inno a i e Food Science & Eme ging Technologies, 55, 88– 96. h ps://doi.o g/10.1016/j.i se .2019.05.001 das chagas, e. g. l., anin, F. M., dos San os ga cia, . A., yoshida, c. M. P., & de ca alho, R. A. (2021). en ichmen o an ioxidan s compounds in cookies p oduced wi h camu-camu (My cia ia dubia) cop oduc s powde s. LWT, 137, 110472. h ps://doi.o g/10.1016/j.lw .2020.110472 de A aújo, F. F., de Paulo Fa ias, d., ne i-numa, i. A., dias-Audibe , F. l., dela io i, J., de Souza, F. g., ca ha ino, R. R., do Sac amen o, c. K., & Pas o e, g. M. (2021). chemical cha ac e iza ion o Eugenia s ipi a a: A na i e ui om he Amazon ich in nu ien s and sou ce o bioac i e com- pounds. Food Resea ch In e na ional (O awa, On .), 139, 109904. h ps://doi.o g/10.1016/j. ood es.2020.109904 de A aújo, F. F., de Paulo Fa ias, d., ne i-numa, i. A., dias-Audibe , F. l., dela io i, J., de Souza, F. g., ca ha ino, R. R., do Sac amen o, c. K., & Pas o e, g. M. (2021). gas oin es inal bioaccessibili y and bioac i i y o phe- nolic compounds om a açá-boi ui . LWT, 135, 110230. h ps://doi.o g/10.1016/j.lw .2020.110230 de oli ei a, M. do. S. P., & Schwa z, g. (2018). Açaí—Eu e pe ole acea. in Exo ic F ui s (pp. 1–5). else ie . h ps://doi. o g/10.1016/B978-0-12-803138-4.00002-2 de Souza ca alho, l. M., lemos, M. c. M., Sanches, e. A., da Sil a, l. S., de A aújo Beze a, J., Aguia , J. P. l., das chagas do Ama al Souza, F., Al es Filho, e. g., & campelo, P. h. (2020). imp o emen o he bioaccessibili y o bio- ac i e compounds om Amazon ui s ea ed using high ene gy ul asound. Ul asonics Sonochemis y, 67, 105148. h ps://doi.o g/10.1016/j.ul sonch.2020.105148 dias-Souza, M. ., dos San os, R. M., ce á olo, i. P., cosenza, g., Fe ei a Ma çal, P. h., & Figuei edo, F. J. B. (2018). Eu e pe ole acea pulp ex ac : chemical analyses, an ibio- ilm ac i i y agains S aphylococcus au eus, cy o oxici y and in e e ence on he ac i i y o an imic obial d ugs. Mic obial Pa hogenesis, 114, 29–35. h ps://doi. o g/10.1016/j.micpa h.2017.11.006 do nascimen o Sil a, n. R. R., ca alcan e, R. B. M., & da Sil a, F. A. (2023). nu i ional p ope ies o Bu i i (Mau i ia lexuosa) and heal h bene i s. Jou nal o Food Composi ion and Analysis, 117, 105092. h ps://doi.o g/10.1016/j. j ca.2022.105092 dos San os, M. dF. g Mamede, R. . S Ru ino, M. dS. M de B i o, e. S., & Al es, R. e. (2015). Amazonian na i e Palm F ui s as Sou ces o An ioxidan Bioac i e compounds. An ioxidan s (Basel, Swi ze land), 4(3), 591–602. h ps:// doi.o g/10.3390/an iox4030591 dua e, o. (2011). cocona (Solanum sessili lo um dunal). in Pos ha es Biology and Technology o T opical and Sub opical